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Specific blood-derived cells promote survival in heart attack model
Date:6/16/2010

they transplanted the MDs into animal models of myocardial infarction, the cells secreted high levels of a variety of growth factors that provided anti-inflammatory properties and also played a role in protecting cells of the heart tissues (cardiomyocytes) from programmed cell death (apoptosis).

The researchers also noted that the majority of MDs did not survive more than two weeks in vitro, suggesting that the cells have an effect shortly after injection.

"Dr. Galipeau's group have clearly demonstrated a beneficial effect of the MDs on myocardial improvement in the post-myocardial infarction remodeling process," said Amit N. Patel, director of cardiovascular regenerative medicine at the University of Utah and section editor for Cell Transplantation." These results further demonstrate the benefits of bone marrow derived cells for cardiac cell therapy."


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Contact: David Eve
celltransplantation@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

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