Navigation Links
Special issue of Gut Microbes on Helicobacter pylori
Date:11/18/2013

A special issue on Helicobacter pylori has been published by Landes Bioscience (Austin, TX USA). The articles contained in this special issue of the journal Gut Microbes have been authored by world-class investigators and provide new insights into the pathophysiology, diagnosis, prevention, and treatment of this microbe.

Helicobacter pylori is a gram-negative, microaerophilic bacterium found in the stomach. Identified in the early 1980s, it was shown to be present in patients with chronic gastritis and gastric ulcers, conditions that were not previously believed to have a microbial cause. It is also linked to the development of duodenal ulcers and stomach cancer. However, in over 80% of carriers, H. pylori does not cause symptoms and it has been suggested that the bacterium may play an important role in the natural stomach ecology. H. pylori is the most common bacterial infection worldwide, with more than half of the world's population harboring the bacterium in the upper gastrointestinal tract. While incidence is decreasing in Western countries, H. pylori infection is highly prevalent in developing countries. In the absence of targeted antimicrobial therapy, colonization typically lasts for decades.

Dr Richard Peek from Vanderbilt-Ingram Cancer Center and Cancer Biology (Nashville, TN USA) has worked with the editorial team of Gut Microbes to organize this special issue on H. pylori. Papers in the issue discuss the role of childhood infection in the sequelae of H. pylori disease (Guillermo Perez-Perez), how glyco-conjugates promote virulence of H. pylori (M Stephen Trent), interplay of various H. pylori factors with host protein receptors (Steffen Backert), the role of chronic inflammation and oxidative stress in H. pylori induced gastric cancer (Keith T Wilson), diet, microbial virulence, and H. pylori induced gastric cancer (Timothy L Cover), consequences of H. pylori infection in children in developing countries (Jean E Crabtree), role of the gastrointestinal microbiome in H. pylori pathogenesis (James G Fox), biomarkers of H. pylori associated gastric cancer (Jay V Solnick), H. pylori therapies in light of evolving resistance (Francis Mgraud), benefits of H. pylori treatment in childhood (Karen J Goodman), vaccination against H. pylori (Steven J Czinn), and a study investigating the influence of H. pylori on hepatitis C virus-associated liver cancer.

In an accompanying editorial, Dr Peek highlights the importance of understanding the relationship between H. pylori infection and carcinogenesis. He writes, "Delineation of bacterial, host, and environmental mediators that augment gastric cancer risk has profound ramifications for both physicians and biomedical researchers, as such findings will not only focus prevention approaches that target H. pylori-infected human populations at increased risk for stomach cancer, but will also provide mechanistic insights into inflammatory carcinomas that develop beyond the gastric niche." The full issue is available at the following link: http://www.landesbioscience.com/journals/gutmicrobes/toc/volume/4/issue/6/


'/>"/>

Contact: Andrew Thompson
andrew@landesbioscience.com
Landes Bioscience
Source:Eurekalert

Related biology news :

1. Walgreens Mike Ellis Named First President of National Association of Specialty Pharmacy (NASP)
2. Genetics in Medicine publishes special issue dedicated to genomics in electronic health records
3. Journal of Spinal Cord Medicine publishes special issue on assistive technology
4. RNA-interference pesticides will need special safety testing
5. CARE Pharmacies Joins National Association of Specialty Pharmacy (NASP) as a Founding Corporate Member
6. AegisCare Offers Specialized Home Health Care for Dementia and Alzheimers Patients
7. NASP and ASCP Discuss Future of Specialty Pharmacy in Aging Market at Upcoming ASCP Conference
8. More food and greener farming with specialised transporters for plants
9. Geosphere adds 2 new special issue themes
10. Beckers Spine Review Releases List of 50 Spine Surgeons & Specialists Researching Biologics for Spine Treatments
11. Biological wires carry electricity thanks to special amino acids
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2016)... November 22, 2016 According to the new market ... Print, Face, Vein, Signature, Voice), Multi-Factor), Component (Hardware and Software), Function (Contact ... MarketsandMarkets, the market is expected to grow from USD 10.74 Billion in ... 16.79% between 2016 and 2022. Continue Reading ... ...
(Date:11/17/2016)... CITY OF INDUSTRY, Calif. , Nov. 17, 2016  AIC announces that it ... about using NVMe storage servers in organizations that require high-performance scale-out plus high speed data transfer ... ... ... Setting ...
(Date:11/14/2016)... , Nov. 14, 2016  Based on ... market, Frost & Sullivan recognizes FST Biometrics ... Award for Visionary Innovation Leadership. FST Biometrics ... biometric identification market by pioneering In Motion ... for instant, seamless, and non-invasive verification. This ...
Breaking Biology News(10 mins):
(Date:12/8/2016)...  HedgePath Pharmaceuticals, Inc. (OTCQX: HPPI), a clinical ... to commercialize innovative therapeutics for patients with cancer, ... approved for trading on the OTCQX U.S. market. ... effective today, under the ticker symbol "HPPI." ... must meet high financial standards, follow best practice ...
(Date:12/8/2016)... Dec. 8, 2016 Eutilex Co. Ltd. today ... (US $18.9M) Series A financing. This financing round included ... Venture and SNU Bio Angel. This new funding brings ... KRW (US $27.7M) since its founding in 2015. ... the development and commercialization of its immuno-oncology programs, expand ...
(Date:12/8/2016)... Dec. 8, 2016   Biocept, Inc . ... provider of clinically actionable liquid biopsy tests to ... clinical data featuring its Target Selectorâ„¢ Circulating Tumor ... for the detection of actionable biomarkers in patients ... sponsored by Sara Cannon Research Institute (SCRI), the ...
(Date:12/7/2016)... ... December 07, 2016 , ... A new ... the setting of previously treated, advanced pancreatic cancer, liquid biopsies are not yet ... population and timing of blood sampling may improve the value of a blood-based ...
Breaking Biology Technology: