New Rochelle, NY, September 10, 2010The glycome, encompassing all of the complex sugars produced by an organism, is comprised of multiple families of molecules whose function in the human body is often determined by the structure, composition, and placement of the attached sugars, as explored in a comprehensive look at the field of glycomics in a group of key articles in OMICS: A Journal of Integrative Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The relevant articles are available free online at www.liebertpub.com/omi
Guest Editors Jeremy E. Turnbull, from the University of Liverpool, U.K., and Ram Sasisekharan, from Massachusetts Institute of Technology (Cambridge, MA), have compiled a series of informative articles that present the most recent scientific advances in this rapidly evolving field of study. In the editorial entitled, "Glycomics: Technologies Taming a Frontier Omics Field," they describe how the challenges associated with studying the complex field of glycomics have given rise to a set of robust and high-throughput research tools capable of probing this diverse family of compounds and producing a wealth of information about how they function and help to regulate biological systems.
This Special Issue takes a comprehensive approach to glycomics, incorporating a broad range of glycan-conjugated compounds, such as glycoproteins, glycolipids, and proteoglycans. In particular, for example, are articles that focus on the sialome, a subclass of the glycome comprised of sialic acid-based core structures present on the surface of cells. Miriam Cohen and Ajit Varki, from University of California, San Diego, in La Jolla, coauthored "The SialomeFar More than the Sum of its Parts." They describe the sialome as being analogous to the canopy of a forest, covering the cell surface with an array of complex
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Mary Ann Liebert, Inc./Genetic Engineering News