Navigation Links
Special focus on glycomics in OMICS: A Journal of Integrative Biology
Date:9/10/2010

New Rochelle, NY, September 10, 2010The glycome, encompassing all of the complex sugars produced by an organism, is comprised of multiple families of molecules whose function in the human body is often determined by the structure, composition, and placement of the attached sugars, as explored in a comprehensive look at the field of glycomics in a group of key articles in OMICS: A Journal of Integrative Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The relevant articles are available free online at www.liebertpub.com/omi

Guest Editors Jeremy E. Turnbull, from the University of Liverpool, U.K., and Ram Sasisekharan, from Massachusetts Institute of Technology (Cambridge, MA), have compiled a series of informative articles that present the most recent scientific advances in this rapidly evolving field of study. In the editorial entitled, "Glycomics: Technologies Taming a Frontier Omics Field," they describe how the challenges associated with studying the complex field of glycomics have given rise to a set of robust and high-throughput research tools capable of probing this diverse family of compounds and producing a wealth of information about how they function and help to regulate biological systems.

This Special Issue takes a comprehensive approach to glycomics, incorporating a broad range of glycan-conjugated compounds, such as glycoproteins, glycolipids, and proteoglycans. In particular, for example, are articles that focus on the sialome, a subclass of the glycome comprised of sialic acid-based core structures present on the surface of cells. Miriam Cohen and Ajit Varki, from University of California, San Diego, in La Jolla, coauthored "The SialomeFar More than the Sum of its Parts." They describe the sialome as being analogous to the canopy of a forest, covering the cell surface with an array of complex structures that differ in the nine-carbon sugars that comprise their backbone, how they are attached and arranged on the cell membrane, and their overall structure. In the article, "Proteoglycomics: Recent Progress and Future Challenges," Mellisa Ly, Tatiana Laremore, and Robert Linhardt, from Rensselaer Polytechnic Institute (Troy, NY), describe the unique challenges involved in characterizing the composition, structure, and structure-function relationships of proteoglycans, which are comprised of core proteins modified through the attachment of varied sugar structures.

"Although glycomics may still be a frontier omics field, we believe that it has a bright future in the postgenome era," says Jeremy Turnbull. "Glycosylation of biomolecules alters their biological function and, in some cases, the glycans themselves have intrinsic and independent functions. This affords diverse opportunities for subtle regulation of biological processes at a higher level of complexity than DNA or proteins."


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert

Related biology news :

1. UCLA, Japanese company to collaborate on specialized nano-imaging instrumentation
2. Special edition journal provides new perspectives and guidance for managing white pine blister rust
3. Ecologists to discuss impacts of mountaintop mining at special ESA symposium
4. Blind mice can see thanks to special retinal cells
5. UCR entomologists to develop special bacteria to combat spread of mosquito-borne diseases
6. Harvards Wyss Institute uses natures design principles to create specialized nanofabrics
7. Comprehensive overview of Childrens Interstitial Lung Disease (chILD) in special issue of Pediatric Allergy, Immunology, and Pulmonology
8. Aphids evolved special, surprising talents
9. Oil Refineries Announces Delay to Annual & Special General Meeting
10. Society of Interventional Radiology, Custom Computer Specialists announce HI-IQ licensing agreement
11. Intense sweets taste especially good to some kids
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... UBM,s Advanced Design and Manufacturing event in ... and evolving technology through its 3D Printing and Smart ... the expo portion of the event and feature a ... on trending topics within 3D printing and smart manufacturing. ... will take place June 13-15, 2017 at the Jacob K. ...
(Date:4/11/2017)... 11, 2017 NXT-ID, Inc. (NASDAQ:   ... announces the appointment of independent Directors Mr. Robin D. ... Board of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , ... forward to their guidance and benefiting from their considerable expertise ...
(Date:4/4/2017)... NEW YORK , April 4, 2017   ... solutions, today announced that the United States Patent and ... The patent broadly covers the linking of an iris ... the same transaction) and represents the company,s 45 th ... our latest patent is very timely given the multi-modal ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... August 15, 2017 , ... Nanomedical Diagnostics ... biotherapeutics development, announces the launch of the new NHS Agile biosensor chip ... binding data for a wide range of molecules, including small and large molecules, ...
(Date:8/15/2017)... ... August 15, 2017 , ... ... of 6” modular downlights designed to stay tightly sealed and perform efficiently for ... damp and wet location listings just aren't enough, such as: hospitals; behavioral health ...
(Date:8/15/2017)... ... 2017 , ... JULABO USA introduces its new website ... it easy to navigate through the site whether you’re in the office, in ... educational industry content and visit the company’s social media accounts, all on one ...
(Date:8/14/2017)... ... 2017 , ... The Conference Forum has confirmed the one-day agenda ... September 6, 2017 at the Marriott Copley Place in Boston, MA. , Returning as ... Regulatory Strategy, Pfizer Innovative Research Lab, Pfizer, who leads 19 industry speakers in discussing ...
Breaking Biology Technology: