Navigation Links
Special focus on glycomics in OMICS: A Journal of Integrative Biology

New Rochelle, NY, September 10, 2010The glycome, encompassing all of the complex sugars produced by an organism, is comprised of multiple families of molecules whose function in the human body is often determined by the structure, composition, and placement of the attached sugars, as explored in a comprehensive look at the field of glycomics in a group of key articles in OMICS: A Journal of Integrative Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. ( The relevant articles are available free online at

Guest Editors Jeremy E. Turnbull, from the University of Liverpool, U.K., and Ram Sasisekharan, from Massachusetts Institute of Technology (Cambridge, MA), have compiled a series of informative articles that present the most recent scientific advances in this rapidly evolving field of study. In the editorial entitled, "Glycomics: Technologies Taming a Frontier Omics Field," they describe how the challenges associated with studying the complex field of glycomics have given rise to a set of robust and high-throughput research tools capable of probing this diverse family of compounds and producing a wealth of information about how they function and help to regulate biological systems.

This Special Issue takes a comprehensive approach to glycomics, incorporating a broad range of glycan-conjugated compounds, such as glycoproteins, glycolipids, and proteoglycans. In particular, for example, are articles that focus on the sialome, a subclass of the glycome comprised of sialic acid-based core structures present on the surface of cells. Miriam Cohen and Ajit Varki, from University of California, San Diego, in La Jolla, coauthored "The SialomeFar More than the Sum of its Parts." They describe the sialome as being analogous to the canopy of a forest, covering the cell surface with an array of complex structures that differ in the nine-carbon sugars that comprise their backbone, how they are attached and arranged on the cell membrane, and their overall structure. In the article, "Proteoglycomics: Recent Progress and Future Challenges," Mellisa Ly, Tatiana Laremore, and Robert Linhardt, from Rensselaer Polytechnic Institute (Troy, NY), describe the unique challenges involved in characterizing the composition, structure, and structure-function relationships of proteoglycans, which are comprised of core proteins modified through the attachment of varied sugar structures.

"Although glycomics may still be a frontier omics field, we believe that it has a bright future in the postgenome era," says Jeremy Turnbull. "Glycosylation of biomolecules alters their biological function and, in some cases, the glycans themselves have intrinsic and independent functions. This affords diverse opportunities for subtle regulation of biological processes at a higher level of complexity than DNA or proteins."


Contact: Vicki Cohn
Mary Ann Liebert, Inc./Genetic Engineering News

Related biology news :

1. UCLA, Japanese company to collaborate on specialized nano-imaging instrumentation
2. Special edition journal provides new perspectives and guidance for managing white pine blister rust
3. Ecologists to discuss impacts of mountaintop mining at special ESA symposium
4. Blind mice can see thanks to special retinal cells
5. UCR entomologists to develop special bacteria to combat spread of mosquito-borne diseases
6. Harvards Wyss Institute uses natures design principles to create specialized nanofabrics
7. Comprehensive overview of Childrens Interstitial Lung Disease (chILD) in special issue of Pediatric Allergy, Immunology, and Pulmonology
8. Aphids evolved special, surprising talents
9. Oil Refineries Announces Delay to Annual & Special General Meeting
10. Society of Interventional Radiology, Custom Computer Specialists announce HI-IQ licensing agreement
11. Intense sweets taste especially good to some kids
Post Your Comments:
(Date:4/13/2017)... According to a new market research report "Consumer ... Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region - ... to grow from USD 14.30 Billion in 2017 to USD 31.75 Billion ... ... MarketsandMarkets Logo ...
(Date:4/6/2017)... , April 6, 2017 Forecasts ... ANPR, Document Readers, by End-Use (Transportation & Logistics, Government ... Oil, Gas & Fossil Generation Facility, Nuclear Power), Industrial, ... Other) Are you looking for a definitive ... ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... compared the implantation and pregnancy rates in frozen and fresh in vitro ... of progesterone and maternal age to IVF success. , After comparing the results ...
(Date:10/10/2017)... ... October 10, 2017 , ... San Diego-based team building and cooking events ... announced today. The bold new look is part of a transformation to increase ... a significant growth period. , It will also expand its service offering from its ...
(Date:10/10/2017)... ... October 10, 2017 , ... For ... has won a US2020 STEM Mentoring Award. Representatives of the FirstHand program travelled ... Volunteer Experience from US2020. , US2020’s mission is to change the trajectory of ...
(Date:10/10/2017)... , Oct. 10, 2017 International research firm Parks ... Strategy, will speak at the TMA 2017 Annual Meeting , October ... trends in the residential home security market and how smart safety and ... Parks ... "The residential ...
Breaking Biology Technology: