Navigation Links
Spaceflight shown to alter ability of bacteria to cause disease
Date:9/24/2007

Space flight has been shown to have a profound impact on human physiology as the body adapts to zero gravity environments. Now, a new study led by researchers from the Biodesign Institute at Arizona State University has shown that the tiniest passengers flown in spacemicrobescan be equally affected by space flight, making them more infectious pathogens.

Space flight alters cellular and physiological responses in astronauts including the immune response, said Nickerson, who led a project aboard NASAs space shuttle mission STS-115 (September 2006) involving a large, international collaboration between NASA, ASU and 12 other research institutions. However, relatively little was known about microbial changes to infectious disease risk in response to space flight.

Cheryl Nickerson and lead author James Wilson, both professors in ASUs School of Life Sciences, have performed the first study of its kind to investigate the effect of space flight on the genetic responses and disease-causing potential, or virulence, of Salmonella typhimurium, the main bacterial culprit of food poisoning. Their results, published in the journal Proceedings of the National Academy of Sciences (www.pnas.org.cgi/doi/10.1073/pnas.0707), reveal a key role for a master regulator, called Hfq, in triggering the genetic changes that show an increase in the virulence of Salmonella as a result of spaceflight. The results of these studies hold potential to greatly advance infectious disease research in space and here on Earth, and may lead to the development of new therapeutics to treat and prevent infectious disease.

To study the effects of space flight, Nickerson and colleagues sent specially contained tubes of Salmonella in an experimental payload aboard the Space Shuttle Atlantis. The tubes of bacteria were placed in triple containment for safety and posed no threat to the health and safety of the crew during or
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert

0

GOOD

Page: 1 2 3 4

Related biology news :

1. Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
2. Topical treatment shown to inhibit HIV and herpes simplex virus infection
3. Controversial drug shown to act on brain protein to cut alcohol use
4. Enzyme shown to help protect genomic stability
5. Novel gene-silencing nanoparticles shown to inhibit Ewings sarcoma
6. New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
7. First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown
8. Ultra low-dose estrogen shown safe for post-menopausal women
9. Vaccine shown effective against chancroid
10. Protein shown to rally biological clock
11. Active ingredient in common Chinese herb shown to reduce hypertension
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... at Emory University, along with partners at the ... million grant over four years to establish the ... Research Center: Understanding Lifetime Exposures). The grant is ... United States. , The HERCULES Center is ... Sciences (NIEHS) of the National Institutes of Health ...
(Date:5/23/2013)... the overall health, development, and academic success of ... ensuring that all students have opportunities to engage ... vigorous or moderate-intensity physical activity, says a new ... estimates suggest that only about half of school-age ... health and development. The report recommends that ...
(Date:5/23/2013)... treating cerebral palsy with autologous cord blood. Following a ... old boy had been in a persistent vegetative state ... after treatment with the cord blood containing stem cells, ... child learned to speak simple sentences and to move. ... dispel the long-held doubts about the effectiveness of the ...
Breaking Biology News(10 mins):Emory, Georgia Tech receive first human exposome center grant in US 2Emory, Georgia Tech receive first human exposome center grant in US 3Schools should provide opportunities for 60 minutes of daily physical activity to all students 2Schools should provide opportunities for 60 minutes of daily physical activity to all students 3First successful treatment of pediatric cerebral palsy with autologous cord blood 2
... more allergies one has, the lower the risk of ... in Cancer Epidemiology, Biomarkers & Prevention , a ... Researchers from the University of Illinois at Chicago, used ... for 419 patents with glioma and 612 cancer-free patients ...
... gibbons (genus Nomascus ) live in dense Asian rainforest, ... their environment, they communicate with other gibbons by singing. Both ... find a mate, and couples also sing duets to strengthen ... access journal BMC Evolutionary Biology describes how gibbon ...
... An international team of researchers has made new links between ... common form of inflammatory bowel disease (IBD). The new findings ... associated with inflammatory bowel disease to 99. The results ... bodies maintain the lining of the intestinal wall, which are ...
Cached Biology News:Allergies lower risk of low- and high-grade glioma 2Research links 29 genome regions with common form of inflammatory bowel disease 2Research links 29 genome regions with common form of inflammatory bowel disease 3
(Date:5/23/2013)... 23, 2013 Can economic incentives such ... motivate members of the public to increase their donations ... Johns Hopkins Carey Business School Assistant Professor Mario ... to a large body of recent research that supports ... 24, 2013, issue of Science that the World Health ...
(Date:5/23/2013)... , May 23, 2013  Rahal Letterman Lanigan ... human cord blood stem cell banking and therapeutics, announced ... the No. 16 Acorn Stairlifts Indy car driven by ... the remainder of the IZOD IndyCar 2013 season.   ... will work to support awareness of umbilical cord blood ...
(Date:5/23/2013)... , May 23, 2013  Saddleback Memorial Medical ... recently became the first hospital on the West Coast ... This new surgical option provides women with a state-of-the-art, ... Marc Winter , M.D., a highly ... surgeon and medical director of minimally invasive surgery at ...
(Date:5/23/2013)... , May 23, 2013 Z Trim Holdings, ... ingredients to a variety of industries, announced that Chef ... panel discussion at this year,s National Restaurant Association ("NRA") ... on behalf of the Research Chefs Association.  Chef Ryan ... The Good, the Bad and the Ugly," joining four ...
Breaking Biology Technology:Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 3StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 2Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 3Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 2Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 3
... Research Group, Inc.,released its Fourth Annual Nephrology TreatmentTrends ... management of,renal anemia and bone and mineral metabolism ... on responses to an online survey, completed by,305 ... In the anemia market, the vast majority ...
... Effect in Preclinical Model of ... Parkinson,s ... Inc.,(NASDAQ: VSGN ; TSX:VAS), a biotechnology company engaged in the ... process associated with the development and progression of,cardiovascular and neurodegenerative ...
... YORK, Jan. 28 The Medefield Group, the ... market research, consulting,and communications companies, is pleased to ... After another year of unprecedented growth,attributed to Medefield,s ... client base, the company is adding to its,ever-growing ...
Cached Biology Technology:BioTrends Releases Fourth Annual Nephrology TreatmentTrends Publication Highlighting Market Trends for Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism 2Vasogen's Research Published in European Journal of Neuroscience 2Vasogen's Research Published in European Journal of Neuroscience 3Vasogen's Research Published in European Journal of Neuroscience 4Vasogen's Research Published in European Journal of Neuroscience 5Medefield Announces New Appointments to North American Business Unit 2
...
... G bind specifically to Fc regions of ... G conjugates are commonly used as affinity ... subtypes from serum, hybridoma ascites fluids, tissue ... reagents are also commonly used to capture ...
... environmental and pathophysiological stressful conditions trigger the ... as heat shock proteins (HSPs), more appropriately ... The Hsp90 family of proteins in mammalian ... Grp94, and Trap-1 (Hsp75). It was found ...
... Competitor Assay Kits provide a sensitive and ... AR ligands using fluorescence polarization (FP). The ... protein tagged with His and GST [AR-LBD ... ligand (Fluormone AL Green in the green ...
Biology Products: