Navigation Links
Soy may stop prostate cancer spread
Date:11/8/2010

CHICAGO --- Northwestern Medicine researchers at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University have found that a new, nontoxic drug made from a chemical in soy could prevent the movement of cancer cells from the prostate to the rest of the body.

These findings will be presented at the Ninth Annual American Association for Cancer Research Frontiers in Cancer Prevention Research Conference.

Genistein, a natural chemical found in soy, is being used in the lab of Raymond Bergan, M.D., the director of experimental therapeutics at the Lurie Cancer Center, to inhibit prostate cancer cells from becoming metastatic and spreading to other parts of the body. So far the cancer therapy drug has worked in preclinical animal studies and now shows benefits in humans with prostate cancer.

A recent phase II randomized study of 38 men with localized prostate cancer found that genistein, when given once a day as a pill, one month prior to surgery, had beneficial effects on prostate cancer cells.

Researchers examined the cancer cells from the subjects' prostates after surgery and found that genistein increased the expression of genes that suppress the invasion of cancer cells and decreased the expression of genes that enhance invasion.

"The first step is to see if the drug has the effect that you want on the cells and the prostate, and the answer is 'yes, it does,'" said Bergan, a professor of hematology and oncology at Northwestern University Feinberg School of Medicine and a physician at Northwestern Memorial Hospital.

The next step is to conduct another phase II study to see if the drug can stop the cancer cells from moving out of the prostate and into the rest of the body, Bergan said. If confirmed, Bergan said this could be the first therapy for any cancer that is non-toxic and targets and inhibits cancer cell movement.

"All therapies designed to stop cancer cell movement that have
'/>"/>

Contact: Erin White
ewhite@northwestern.edu
847-491-4888
Northwestern University
Source:Eurekalert

Page: 1 2

Related biology news :

1. UCLA researchers discover a potential target for therapy for patients with a deadly prostate cancer
2. Prostate cancers multiple personalities revealed
3. Vitamin E in front line of prostate cancer fight
4. Rutgers part of team awarded $3.3 million National Institutes of Health grant for prostate cancer research
5. Gene variations that alter key enzyme linked to prostate cancer
6. Atrazine causes prostate inflammation in male rats and delays puberty
7. Rutgers researchers assess severity of prostate cancers using magnetic resonance imaging
8. Mechanism for link between high fat diet and risk of prostate cancer and disorders unveiled
9. Innovation and current status of prostate cancer gene therapy featured in Human Gene Therapy
10. UNC team finds new target for treatment of advanced prostate cancer
11. Thymoquinone induced oxidative stress targets highly aggressive prostate cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Mo. April 17 In the most densely forested ... forests reflect two centuries of human needs, values and ... and clearing forests for agriculture and development, have set ... a U.S. Forest Service study reports. , The report ... conditions and management needs in the Northern United States ...
(Date:4/17/2014)... 17, 2014The development of stem cell therapies to cure ... characterize stem cell populations based on cell surface markers. ... new marker that is highly expressed in a type ... which they describe in an article in BioResearch ... Liebert, Inc., publishers. The article is available free on ...
(Date:4/17/2014)... ALBUQUERQUE, N.M. A credit-card-sized anthrax detection cartridge developed ... small business makes testing safer, easier, faster and cheaper. ... causes anthrax, is commonly found in soils all over ... illness in both humans and animals. The bacteria can ... to B. anthracis may occur through skin ...
Breaking Biology News(10 mins):Five anthropogenic factors that will radically alter northern forests in 50 years 2Five anthropogenic factors that will radically alter northern forests in 50 years 3Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3
... Two years ago, a group of friends were enjoying ... Germany when their conversation turned to the health benefits which ... making wine, by-products are left over which are often just ... by-products contain the goodness of wine in an even more ...
... presented in the name of Engineering Conferences International ... be awarded to Professor Sakayu Shimizu of Kyoto ... both fundamental and applied sciences. He has contributed ... functions, reactions and enzymes as biotechnological tools for ...
... by Hebrew University of Jerusalem researchers of an additional role ... step in world-wide efforts to develop genetic regulation aimed at ... The molecule, known as Lysyl-tRNA synthetase (or LysRS ... the cell, where it has long been recognized for its ...
Cached Biology News:The wonders of wine 2The wonders of wine 3Sakayu Shimizu of Kyoto University recipient of 2009 Enzyme Engineering Award 2
(Date:1/14/2014)... Carahsoft and CDS Federal Services have scheduled a ... EST (11am PST), “Natural Language Processing: Converting Raw Data ... can turn raw, heterogeneous data into actionable knowledge to ... webinar will last approximately one hour. , Synopsis: Big ...
(Date:1/14/2014)... Texas , Jan. 14, 2014 The ... and research medicinal plants and therapeutic derivatives thereof ... health professionals, and researchers about the challenges of ... http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The Society ...
(Date:1/14/2014)... January 14, 2014 Global Record ... innovative information technology solutions for patients, physicians, the ... stakeholders, announced today the signing of a three-year ... and Drug Administration (FDA). This initiative is ...
(Date:1/14/2014)... Altadena, CA (PRWEB) January 14, 2014 ... Angeles County), California, and Montreal, Canada, has big ideas ... and non-fiction. The press's goals are to produce high-quality, ... e-books to support local businesses. , The first ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... PDL BioPharma, Inc. (PDL) (Nasdaq: PDLI ) today announced ... officer, will present at the Oppenheimer 20th Annual Healthcare Conference ... 9:40 a.m. Eastern Time , To access the live and ... company,s website at http://www.pdl.com and click "Investors." Please ...
... 27 Organogenesis, Inc. Chief Medical Officer Dr. Damien ... prestigious TEDMED medical innovation conference beginning today in San ... Come From?" will outline developments in the emerging and ... of patient lives. , The field of regenerative medicine ...
... PRINCETON, N.J., Oct. 27 Soligenix, Inc., (Soligenix or ... DOR BioPharma, Inc., a late-stage biotechnology company, announced today ... a company overview highlighting recent developments at the BIO ... Thursday, October 29, 2009 at 1:00 PM PDT at ...
Cached Biology Technology:Dr. Damien Bates of Organogenesis Speaks on Regenerative Medicine for Opening Night of TEDMED Conference 2Soligenix to Present at 8th Annual BIO Investor Forum 2Soligenix to Present at 8th Annual BIO Investor Forum 3Soligenix to Present at 8th Annual BIO Investor Forum 4
Human SDNSF/MCFD2 Biotinylated Affinity Purified PAb...
dithiothreitol, sulfhydryl reducing agent, C4H10O2S2; MW: 154.24, 97% pure (minimum), CAS No: 27565-41-9, store at -20 C ...
Human SCP3 Affinity Purified Polyclonal Ab Keywords: Spermatogenesis, meiosis Protein Family: Cell Cycle...
Request Info...
Biology Products: