Navigation Links
Southampton scientists herald significant breakthrough in study of chlamydia
Date:10/13/2011

A breakthrough in the study of chlamydia genetics could open the way to new treatments and the development of a vaccine for this sexually transmitted disease.

For decades research progress has been hampered because scientists have been prevented from fully understanding these bacteria as they have been unable to manipulate the genome of Chlamydia trachomatis.

Now researchers in Southampton have made a significant breakthrough in accessing the chlamydial genome and believe it could pave the way for more effective treatment of the disease.

They hope that it could eventually lead to the development of a vaccine for C. trachomatis that is the major cause of sexually transmitted infections in the UK.

The infection is part of a 'silent epidemic' as most cases do not show symptoms and are left untreated. It can cause pelvic inflammatory disease and lead to scarring of the Fallopian tubes causing infertility and higher risk of ectopic pregnancy.

The research was carried out at the Molecular Microbiology Group, at the University of Southampton, in conjunction with the Department of Virology, at the Ben Gurion University of the Negev, in Israel.

Professor Ian Clarke, from the University of Southampton, says: "This is a very significant advance in the study of chlamydia and we are proud to be the first people to achieve this.

"Previously people have been unable to study chlamydial genetics and this has created a barrier to the comprehensive study of this disease.

"We, together with our colleagues in Israel, discovered that by treating the chlamydia with calcium ions we were able to introduce a piece of foreign DNA.

"This will open up the field of chlamydia research and will enable a better understanding of chlamydial genetics. It could lead to the development of new approaches to chlamydial vaccines and therapeutic interventions."

To prove that they had accessed the chlamydial genome, the research team inserted the gene for a fluorescent protein into C. trachomatis which identified the chlamydial-infected cells by making them glow green.


'/>"/>
Contact: Glenn Harris
G.Harris@soton.ac.uk
44-238-059-3212
University of Southampton
Source:Eurekalert

Related biology news :

1. Southampton researchers awarded $28 million to progress pioneering nutrition and respiratory research
2. Southampton scientists to help create a sustainable energy system for the UK
3. National Academy of Sciences recognizes Southampton genetics scientist
4. Scientists move closer to predicting who will and will not fight off severe infections
5. Tagging tumors with gold: Scientists use gold nanorods to flag brain tumors
6. Uncharted territory: Scientists sequence the first carbohydrate biopolymer
7. New drug target for Alzheimers, stroke is discovered by University at Buffalo scientists
8. Scientists discover 3 new gene faults which could increase melanoma risk by 30 percent
9. Scientists identify microbes responsible for consuming natural gas in Deepwater Horizon spill
10. University of Texas marine scientists awarded $5.6 million for study of critical Arctic environment
11. Responsibilities of scientists underlined by scientific community
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/5/2017)... SEATTLE , April 5, 2017  The Allen ... the Allen Cell Explorer: a one-of-a-kind portal and dynamic ... large-scale 3D imaging data, the first application of deep ... edited human stem cell lines and a growing suite ... the platform for these and future publicly available resources ...
(Date:4/4/2017)... , April 4, 2017   EyeLock LLC , ... that the United States Patent and Trademark Office (USPTO) ... covers the linking of an iris image with a ... and represents the company,s 45 th issued patent. ... is very timely given the multi-modal biometric capabilities that ...
(Date:3/30/2017)... 30, 2017 The research team of The ... (3D) fingerprint identification by adopting ground breaking 3D fingerprint minutiae recovery ... of speed and accuracy for use in identification, crime investigation, immigration ... ... A research team ...
Breaking Biology News(10 mins):
(Date:7/18/2017)... ... July 18, 2017 , ... Allotrope ... released the first phase of the Allotrope Framework for commercial use. , The ... created to “not only elevate the critical role of information technology in modern ...
(Date:7/17/2017)... ... 2017 , ... Whitehouse Laboratories is excited to announce that ... series of ISO 80369 standard test procedures. The ISO 80369 series of eight ... systems. With this recent expansion, Whitehouse Labs becomes one of the only facilities ...
(Date:7/17/2017)... ... July 17, 2017 , ... ... today announced safety software company AB Cube has joined its eHealth ... to advance technology innovation across life sciences and healthcare. Under the partnership, ...
(Date:7/17/2017)... , ... July 17, 2017 , ... ... characterized by a wide range of overlapping clinical features. The advancement of targeted ... the field of NDD research and testing. , However, designing a custom ...
Breaking Biology Technology: