Navigation Links
Southampton scientists herald significant breakthrough in study of chlamydia
Date:10/13/2011

A breakthrough in the study of chlamydia genetics could open the way to new treatments and the development of a vaccine for this sexually transmitted disease.

For decades research progress has been hampered because scientists have been prevented from fully understanding these bacteria as they have been unable to manipulate the genome of Chlamydia trachomatis.

Now researchers in Southampton have made a significant breakthrough in accessing the chlamydial genome and believe it could pave the way for more effective treatment of the disease.

They hope that it could eventually lead to the development of a vaccine for C. trachomatis that is the major cause of sexually transmitted infections in the UK.

The infection is part of a 'silent epidemic' as most cases do not show symptoms and are left untreated. It can cause pelvic inflammatory disease and lead to scarring of the Fallopian tubes causing infertility and higher risk of ectopic pregnancy.

The research was carried out at the Molecular Microbiology Group, at the University of Southampton, in conjunction with the Department of Virology, at the Ben Gurion University of the Negev, in Israel.

Professor Ian Clarke, from the University of Southampton, says: "This is a very significant advance in the study of chlamydia and we are proud to be the first people to achieve this.

"Previously people have been unable to study chlamydial genetics and this has created a barrier to the comprehensive study of this disease.

"We, together with our colleagues in Israel, discovered that by treating the chlamydia with calcium ions we were able to introduce a piece of foreign DNA.

"This will open up the field of chlamydia research and will enable a better understanding of chlamydial genetics. It could lead to the development of new approaches to chlamydial vaccines and therapeutic interventions."

To prove that they had accessed the chlamydial genome, the research team inserted the gene for a fluorescent protein into C. trachomatis which identified the chlamydial-infected cells by making them glow green.


'/>"/>
Contact: Glenn Harris
G.Harris@soton.ac.uk
44-238-059-3212
University of Southampton
Source:Eurekalert

Related biology news :

1. Southampton researchers awarded $28 million to progress pioneering nutrition and respiratory research
2. Southampton scientists to help create a sustainable energy system for the UK
3. National Academy of Sciences recognizes Southampton genetics scientist
4. Scientists move closer to predicting who will and will not fight off severe infections
5. Tagging tumors with gold: Scientists use gold nanorods to flag brain tumors
6. Uncharted territory: Scientists sequence the first carbohydrate biopolymer
7. New drug target for Alzheimers, stroke is discovered by University at Buffalo scientists
8. Scientists discover 3 new gene faults which could increase melanoma risk by 30 percent
9. Scientists identify microbes responsible for consuming natural gas in Deepwater Horizon spill
10. University of Texas marine scientists awarded $5.6 million for study of critical Arctic environment
11. Responsibilities of scientists underlined by scientific community
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... , May 24, 2016 Ampronix facilitates superior patient care by providing unparalleled ... medical LCD display is the latest premium product recently added to the range of ... ... ... Sony 3d Imaging- LCD Medical Display- Ampronix News ...
(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
(Date:4/19/2016)... -- The new GEZE SecuLogic access control ... system solution for all door components. It can be ... interface with integration authorization management system, and thus fulfills ... dimensions of the access control and the optimum integration ... considerable freedom of design with regard to the doors. ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... HOUSTON , June 23, 2016 ... agreement with the Cy-Fair Sports Association to serve ... of the agreement, Houston Methodist Willowbrook will provide ... education and connectivity with association coaches, volunteers, athletes ... partner with the Cy-Fair Sports Association and to ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the Industry Network for ... Design Lab . Located in Pasadena, Calif., the Design Lab’s mission is to ... are designed, built and brought to market. , The Design Lab is Supplyframe’s ...
(Date:6/23/2016)... June 23, 2016 ... 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 Published recently ... peer-reviewed journal from touchONCOLOGY, Andrew D Zelenetz ... of cancer care is placing an increasing burden ... expensive biologic therapies. With the patents on many ...
(Date:6/23/2016)... -- Amgen (NASDAQ: AMGN ) today announced a ... sciences incubator to accelerate the development of new therapies ... QB3@953 was created to help high-potential life science and ... stage organizations - access to laboratory infrastructure. ... "Amgen Golden Ticket" awards, providing each winner with one ...
Breaking Biology Technology: