Navigation Links
Sorting out stroking sensations
Date:1/30/2013

e flashes of light in those neurons in an intact mouse while stroking and poking its body," says Anderson. "We took advantage of the fact that these sensory neurons are bipolar in the sense that they send one branch into the skin that detects stimuli, and another branch into the spinal cord to relay the message detected in the skin to the brain."

The team obtained the needed data by placing the mouse under a special microscope with very high magnification and recording the level of fluorescent light in the fibers of neurons in the spinal cord as the animal was stroked, poked, tickled, and pinched. Through a painstaking process of applying stimuli to one tiny area of the animal's body at a time, they were able to confirm that certain neurons lit up only when stroked. A different class of neurons, by contrast, was activated by poking or pinching the skin, but not by stroking.

"Massage-like stroking is a stimulus that, if were we to experience it, would feel good to us, but as scientists we can't just assume that because something feels good to us, it has to also feel good to an animal," says Anderson. "So we then had to design an experiment to show that artificially activating just these neuronswithout actually stroking the mousefelt good to the mouse."

The researchers did this by creating a box that contained left, right, and center rooms connected by little doors. The left and right rooms were different enough that a mouse could distinguish them through smell, sight, and touch. In the left room, the mouse received an injection of a drug that selectively activated the neurons shown to detect massage-like stroking. In the room on the right, the mouse received a control injection of saline. After a few sessions in each outer room, the animal was placed in the center, with the doors open to see which room it preferred. It clearly favored the room where the massage-sensitive neurons were activated. According to Anderson, this was the first time
'/>"/>

Contact: Brian Bell
bpbell@caltech.edu
626-395-5832
California Institute of Technology
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Sorting stem cells
2. Neuroscientists prove ultrasound can be tweaked to stimulate different sensations
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sorting out stroking sensations
(Date:7/30/2015)... MOUNTAIN VIEW, Calif. , July 30, 2015 ... products and services for gene function analysis and ... CRISPR Guide RNA (sgRNA) Knockout Library targeting all ... to specifically and permanently "knock out" a gene,s ... library provides a high throughput screening tool so ...
(Date:7/23/2015)... Aware, Inc. (NASDAQ: AWRE ), a leading ... for its second quarter ended June 30, 2015.  ... million, a decrease of 33% compared to $6.8 million in ... quarter of 2015 was $0.3 million, or $0.01 per diluted ... share, in the same period a year ago.  ...
(Date:7/21/2015)... July 21, 2015  NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce ... announces that it has filed provisional patent 62/192218 ... This invention highlights next generation ... an account, but also the user using unique ...
Breaking Biology News(10 mins):CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 2NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 4
... spontaneous organised motion of a large number of individuals. It ... and groups of insects to shoals of fish, flocks of ... Lobaskin from University College Dublin, Ireland, have uncovered new collective ... EPJ B . Ultimately, this could be used to ...
... only species with a sweet tooth. Research from North Carolina ... Drosophila suzukii ) also prefers sweet, soft fruit giving ... the United States over the past four years and threatens ... U.S. fruit crops. "Because we know that D. ...
... an extinct Australian frog has been revived and reactivated by ... a "dead" cell nucleus into a fresh egg from another ... which uniquely swallowed its eggs, brooded its young ... became extinct in 1983., But the Lazarus Project team has ...
Cached Biology News:Study offers new insights on invasive fly threatening US fruit crops 2Lost frog DNA revived: Lazarus Project 2
(Date:8/3/2015)... (PRWEB) , ... August 03, 2015 , ... Nine field ... Iowa, Illinois and Indiana. Hosted by the Soil Health Partnership , the field ... lasting environmental benefits while potentially increasing farm productivity and income. , Brent Bible has ...
(Date:8/3/2015)... GERMANTOWN, Md. , Aug. 3, 2015   ... it will release first half and second quarter 2015 ... 10 th , 2015.  The Company will host a ... results and provide a general business update. ... (Domestic US) and 1-412-902-4262 (International), and asking to join ...
(Date:8/3/2015)... Kent, WA (PRWEB) , ... August 03, 2015 ... ... TLD3000 and TLD5000 diaphragm vacuum pumps to its comprehensive line of analytical laboratory ... stainless steel valves, these versatile pumps provide a chemically resistant and maintenance-free solution ...
(Date:7/31/2015)... China Cord Blood Corporation (NYSE: CO) ("CCBC" ... provider of cord blood collection, laboratory testing, hematopoietic stem ... that the Company has filed its Annual Report on ... The filed Form 20-F includes audited financial statements for ... 20-F can be accessed by visiting the U.S. Securities ...
Breaking Biology Technology:Soil Health Field Days Kick Off Throughout Midwest 2Soil Health Field Days Kick Off Throughout Midwest 3Intrexon to Announce First Half and Second Quarter 2015 Financial Results and Host Conference Call on August 10th 2Sterlitech Launches New Line of Vacuum Pumps 2China Cord Blood Corporation Files Its Annual Report on Form 20-F 2
... ... will take place on May 16-19, 2010 in Baltimore, MD, USA. This innovative ... their knowledge and experience in process development, crystallization, safety, scale-up, production, and emerging technologies. ... Columbia, MD ...
... Scientists at Queen,s University Belfast are developing new sensors to ... the fight against the threat of terrorist attacks. The ... or crime scene to gather a sample which is then ... of chemicals within seconds. This will allow better, faster decisions ...
... Batteries can power anything from small sensors to ... them smaller but even more powerful, problems can arise ... the devices themselves. University of Missouri researchers are developing ... more efficient. "To provide enough power, we need ...
Cached Biology Technology:17th International Process Development Conference to Feature Presentations on Safety, Process Development, Crystallization, PAT, Scale-Up and Production 2New technology detects chemical weapons in seconds 2Researchers create smaller and more efficient nuclear battery 2
... Corning single use spatulas have been designed ... They are for those interested in eliminating ... spatulas. Each spatula is individually packaged, RNase/DNase ... number is a new product number, created ...
... three-way universal digital valve, just 8 mm in ... functional features in a single glass-reinforced, PBT (Polybutylene ... 8mm in width. , Meets a range of ... psi. , Satisfies a 0.016 sccm leakage specification ...
... versatile system that simultaneously harvests and washes ... into a solid filter supports for analysis ... counter. The FilterMate is ideal for the ... cell proliferation, receptor binding, nucleic acid degradation, ...
... for use with dishes and cell culture ... new product number, created to easily match ... yet, please order under the old Sigma-Aldrich ... assistance. Comp Dim: blade L 1.9 cm ...
Biology Products: