Navigation Links
Some factors that impact islet transplantation explored in Cell Transplantation papers
Date:6/7/2012

Tampa, Fla. (June 6, 2012) Two studies appearing in the current issue of Cell Transplantation (21:2/3), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/, evaluate the transplantation potential and success of islet cells derived from pancreatic tissues, in addition to a clinical study that reports the occurrence of adverse events.

Fresh islets are better than cultured islets

A team of researchers from Baylor Research Institute, Texas and the University Graduate School of Medicine in Okayama, Japan has found that islet cells freshly retrieved from the pancreas are superior to islet cells that have been cultured.

"Isolated islet cells deteriorate rapidly in culture," said study lead author Hirofumi Noguchi. "In our study we compared human fresh islet cells to cultured islets with in vitro and in vivo assays. Human islets, fresh and cultured, were transplanted into diabetic nude mice."

The researchers found that cultured islet yield decreased significantly after 24, 48 and 72 hours. The cultured islets showed a 24 percent loss after 48 hours. By comparison, the blood glucose levels of the diabetic mice were significantly lower with fresh islets after injection.

"Although islet culturing provides many benefits, such as quality testing and stability during travel time and treatment, we advocate avoiding culture time or, at least, curtailing culture time," said Dr. Noguchi. "In the future we will work to optimize the culture conditions to minimize islet loss."

Contact: Hirofumi Noguchi, MD, PhD, Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-chop, Okayama 700-8558, Japan.
Tel. +81-86-235-7257
Fax. +81-86-221-8775
Email

Contact: David Eve
celltransplantation@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Some factors that impact islet transplantation explored in Cell Transplantation papers
2. Time, place and how wood is used are factors in carbon emissions from deforestation
3. Longer sleep times may counteract genetic factors related to weight gain
4. Impaired recovery of Atlantic cod -- forage fish or other factors?
5. Soy-based S-equol supplement reduces metabolic syndrome risk factors
6. Environmental factors in Tiny Tims near fatal illness
7. Study looks at possible link to hyper-excitability factors in epilepsy, autism and more
8. Diabetes risk factors in young Sri Lankans much higher than previously thought
9. No walk in the park: Factors that predict walking difficulty in elderly
10. Genetic factors can predict the progression of Parkinsons disease
11. Risk of stillbirth associated with factors known early in pregnancy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 2014 The Defense Logistics Agency is insourcing its ... counterfeit microcircuits from entering into its supply chain. ... anti-counterfeit initiative dubbed DNA marking. The capability will validate ... throughout the supply chain. The new quality control measures ...
(Date:12/15/2014)... Markets ( http://www.researchandmarkets.com/research/87pph8/global_facial ) has announced the ... report to their offering. ... technology used for the identification of individuals. Facial recognition ... such as nose, jaw edges, mouth, and the distance ...
(Date:12/10/2014)... You,ve been here before: you desperately need to sign into your ... the answer to your secret question. What,s your dog,s birthday? Who ... Labs , a digital infrastructure security company, launches the ... comes with usernames, passwords and PINs – 1U TM ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... discovered that the loss of a protein in the early ... conclusion that the Doctor in Biochemistry reached in the dissertation ... In order to perform the study she began with prior ... appears in the tissue cells that coat the normal lung, ...
... exotic that has visited ecological havoc on numerous Wisconsin lakes ... introduction to Wisconsin waters sometime in the 1950s, the crayfish ... the underwater forests that are critical fish habitat, evicting the ... scooping up fish eggs like so much caviar. , But ...
... age 35 cover their mouth to avoid smiling in public ... Typically, invasive as well as costly treatment options, such as ... to help these individuals hide such stains and boost their ... member and clinician, will explain how a new tooth whitening ...
Cached Biology News:Study shows hope for ridding lakes of clawed invader 2Study shows hope for ridding lakes of clawed invader 3Tetracycline plus teeth equal gray smile 2Tetracycline plus teeth equal gray smile 3
(Date:1/23/2015)... Biofertilizers stimulate microbial activities in soil. These microorganisms ... the activities in the soil or in the rhizosphere. ... stress on reducing environmental pollution and on reducing the ... segments the bio fertilizers market with analysis and forecasting ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Shimadzu ... new UV-1280 multipurpose UV-visible spectrophotometer. Offering wavelength scanning ... instrument is ideal for applications in a variety ... science. , The user-friendly UV-1280 enables intuitive operation, ...
(Date:1/22/2015)... Mass (PRWEB) January 21, 2015 Cambridge Semantics, ... Web technology, today announced that 2014 was a record-breaking year ... the capabilities of the Anzo Smart Data Platform and our ... and utilize insights from diverse data which led to record ...
(Date:1/22/2015)... Diego, California (PRWEB) January 22, 2015 ... Promotional Offer to their comprehensive portfolio of Eppendorf ... allows customers to purchase a Centrifuge 5424/5424 R and ... Bundle of either Eppendorf Research plus or Eppendorf Reference ...
Breaking Biology Technology:Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 2Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 3Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 4Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Cambridge Semantics Announces Record Results for 2014 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2
... ... ... innovative provider of data automation solutions for healthcare providers, today announced the appointment of John ... iSirona,s founder, who will continue to serve as the company,s CEO and retains a seat ...
... BEIJING, Nov. 9 /PRNewswire-Asia-FirstCall/ -- Yongye International, Inc.,(Nasdaq: ... manufacturer, developer,and distributor of Shengmingsu brand plant and animal ... announced that it will conduct a,conference call at 10:00 ... 16, 2009 to discuss results for the quarter ended ...
... CEL-SCI Corporation (NYSE Amex: CVM) announced ... and Microbiology of Northeastern Ohio Universities College of Medicine ... scientists at the Cleveland Clinic and CEL-SCI on CEL-SCI,s ... the 7th GTCbio Vaccine: "All Things Considered" Conference in ...
Cached Biology Technology:iSirona Selects New Chairman of the Board 2Yongye International Announces Conference Call to Discuss Third Quarter 2009 Results 2Yongye International Announces Conference Call to Discuss Third Quarter 2009 Results 3CEL-SCI Collaborators Present Data Suggesting That LEAPS Technology Has Ability to Modify Immune Response 2CEL-SCI Collaborators Present Data Suggesting That LEAPS Technology Has Ability to Modify Immune Response 3
Reported to support murine B lymphocytes, hematopoietic tissue from bone marrow, B cells stimulated with lipopolysaccharide, T lymphocytes, and a variety of hybrid cells....
... F-12 was developed for culturing hybrid cells ... modification consists of doubling the amino acids ... salt concentrations have been altered as well. ... per liter, which may render it unsuitable ...
... Alsevers solution is an isotonic, balanced salt ... preservative, which permits the storage of whole blood ... usage, an equal volume of blood is collected ... but thoroughly, mixed. The solution is placed in ...
... or individual RNA sequences from high throughput synthesis ... RNAs from LC Sciences. These products provide a ... of DESIGNED sequences delivered in a microtube as ... a single verified RNA sequence. This is a ...
Biology Products: