Navigation Links
SomaLogic researchers describe revolutionary new approach to protein analysis and application to early diagnosis of lung cancer
Date:12/2/2010

SOMAmers are essentially small bits of DNA, current DNA measurement technologies like microarrays can be used to measure them and provide a readout of protein or biomarker types and concentrations in a fast and simple analysis. This powerful combination specific binding to individual proteins and DNA-based quantification allows the researchers to accurately detect and measure literally a thousand proteins in as little as a few drops of blood in a single experiment. The first PLoS One paper describes this breakthrough technology in detail, and demonstrates its power through application to samples from patients with chronic kidney disease, finding not only known markers of the disease but many previously unknown protein biomarkers.

Today, single protein biomarkers are the foundation of clinical diagnostics: but both normal and disease biology is far more complex than a single measurement can capture: We need to look at multiple biomarkers, or a signature of proteins, that is truly revealing about health and disease at that moment, said Steve Williams, Chief Medical Officer of SomaLogic. The SOMAmer technology empowers us for the first time to measure real biology in a clinically meaningful way.

In the second PLoS One paper, SomaLogic researchers and their collaborators at multiple sites describe the application of SOMAmers at large scale, uncovering a panel of biomarkers that announce the presence of lung cancer. Lung cancer is the leading cause of cancer deaths, mostly because it is detected under current technologies only at its latest stages. By applying SOMAmer technology to over 1300 clinical samples, the researchers rapidly identified a panel or signature of 12 proteins that together accurately reveal the presence of lung cancer in at-risk patients (e.g., long-term smokers). This finding is the basis for a new diagnostic test under development for clinical application in the next year.

By being able to detect lung cancer early, we fi
'/>"/>

Contact: Jeff Walker
jwalker@somalogic.com
303-625-9021
SomaLogic, Inc.
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers describe first functioning lipidome of mouse macrophage
2. Researchers find link between sugar, diabetes and aggression
3. Snakes on a rope: Researchers take a unique look at the climbing abilities of boa constrictors
4. Researchers kick-start ancient DNA
5. Gene links to anorexia found by Childrens Hospital of Philadelphia researchers
6. UGA researchers identify key enzyme that regulates the early growth of breast cancer cells
7. Researchers insert identification codes into mouse embryos
8. Researchers learn that genetics determine winter vitamin D status
9. Researchers link an African lizard fossil in Africa with the Komodo dragon in Indonesia
10. FSU researchers helping K-12 teachers bring science down to Earth
11. As Arctic temperatures rise, tundra fires increase, researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... a life without light. They emit echolocation sounds and use ... obstacles or prey. In their brains, they have a spatial ... researchers at Technische Universitt Mnchen (TUM) has shown for the ... , Closer objects appear larger , ... the number of activated neurons in its brain increases. As ...
(Date:8/31/2014)... highly infectious bacteria C. diff , that causes ... a team at the University of Leicester. , Using ... it is possible to identify the unique ,smell, of ... diagnosis of the condition., What is more, the Leicester ... strains of the disease simply from their smell ...
(Date:8/31/2014)... in Nature Climate Change , suggests that if ... not exceed, the global targets for total greenhouse gas (GHG) ... should all think carefully about the food we choose and ... world is just one of a number of actions that ... ensure there is enough food for all. , As ...
Breaking Biology News(10 mins):Zooming in for a safe flight 2Scientists develop 'electronic nose' for rapid detection of C. diff infection 2Changing global diets is vital to reducing climate change 2Changing global diets is vital to reducing climate change 3Changing global diets is vital to reducing climate change 4
... clear change in salinity has been detected in the ... global rainfall and evaporation cycle., In a paper published ... the Commonwealth Scientific and Industrial Research Organisation (CSIRO) and ... of salinity in the global ocean during the past ...
... scientists has found there has been a massive reduction in ... of Antarctica.,Comparing detailed measurements taken during the Australian Antarctic program,s ... back to 1970, scientists estimate there has been as much ... Antarctic Bottom Water, the cold dense water that drives global ...
... Berlin, Germany, May 21, 2012 IMPACT World+, ... methodology was launched today in Berlin, Germany during the ... Meeting. The event featured the results of this innovative ... experts and researchers from five countries., The production and ...
Cached Biology News:Earth's water cycle intensifying with atmospheric warming 2Latest Southern Ocean research shows continuing deep ocean change 2Latest Southern Ocean research shows continuing deep ocean change 3Launch of IMPACT World+ 2
(Date:8/28/2014)... A new research platform uses a ... tiny structures undergoing stress and heating, an ... designs for microelectronics and batteries., This new ... about how heating and the surface stress ... Researchers have discussed the merits of surface-stress ...
(Date:8/28/2014)... 2014  Next month, executives from clinical trial marketing firm ... beginning with Patient-Centered Clinical Trials 2014 , to be ... , September 4-5. Patient recruitment experts Bonnie A. ... will share insights on the benefits of employing an ... – from media to mobile apps – can be used ...
(Date:8/28/2014)... work by a Florida State University research team has ... your temperature, emit white light, and convert photon energy ... like a butterfly. , Biwu Ma, associate professor in ... FAMU-FSU College of Engineering, created the molecule in a ... discover that his creation has many other unique capabilities. ...
(Date:8/28/2014)... Boston, MA (PRWEB) August 28, 2014 ... of wholesale construction materials, selected SoundConnect ... of their cloud based audio and web conferencing ... configured to support PrimeSource’s employees’ needs. SoundConnect ... technologies. , PrimeSource Building Products will be ...
Breaking Biology Technology:New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3BBK Worldwide Leads Sessions at Key September Events 2Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 2PrimeSource Chooses SoundConnect as Collaboration Provider 2
... accurately while minimizing ... 6 During his annual,physical check-up in March, David Kelver,s ... the right one looked a bit swollen. The,doctor concluded, however, ... own, and sent him home. Several months later, Kelver, a ...
... showing that Microsoft SQL Server ... 1 petabyte., REDMOND, Wash., Nov. 6 ... management and business,intelligence platform, Microsoft SQL Server 2008, ... scale new heights in data warehousing,and transaction processing., ...
... at Rodman & Renshaw,10th Annual Healthcare Conference" issued on ... over PR Newswire, we are advised by a,representative of ... the first paragraph. Complete, corrected release follows:, , ... the development of microRNA-based diagnostics, announced today it,will present ...
Cached Biology Technology:Cancer Care of Western New York Becomes First Center in Western New York to Treat Cancer with RapidArc(TM) Radiotherapy Technology from Varian Medical Systems 2Cancer Care of Western New York Becomes First Center in Western New York to Treat Cancer with RapidArc(TM) Radiotherapy Technology from Varian Medical Systems 3Cancer Care of Western New York Becomes First Center in Western New York to Treat Cancer with RapidArc(TM) Radiotherapy Technology from Varian Medical Systems 4Could Database Software Help Cure Alzheimer's and Save the Earth? 2Could Database Software Help Cure Alzheimer's and Save the Earth? 3/C O R R E C T I O N -- Rosetta Genomics Ltd/ 2/C O R R E C T I O N -- Rosetta Genomics Ltd/ 3/C O R R E C T I O N -- Rosetta Genomics Ltd/ 4/C O R R E C T I O N -- Rosetta Genomics Ltd/ 5/C O R R E C T I O N -- Rosetta Genomics Ltd/ 6
Mouse monoclonal [6C3] to JAB1 ( Abpromise for all tested applications). entrezGeneID: 10987 SwissProtID: O15386...
Human TGF-beta RIIb Affinity Purified Polyclonal Ab...
Human FGF R2 (alpha isoforms) MAb (Clone 98706)...
dithiothreitol, sulfhydryl reducing agent, C4H10O2S2; MW: 154.24, 97% pure (minimum), CAS No: 27565-41-9, store at -20 C ...
Biology Products: