Navigation Links
SomaLogic researchers describe revolutionary new approach to protein analysis and application to early diagnosis of lung cancer
Date:12/2/2010

SOMAmers are essentially small bits of DNA, current DNA measurement technologies like microarrays can be used to measure them and provide a readout of protein or biomarker types and concentrations in a fast and simple analysis. This powerful combination specific binding to individual proteins and DNA-based quantification allows the researchers to accurately detect and measure literally a thousand proteins in as little as a few drops of blood in a single experiment. The first PLoS One paper describes this breakthrough technology in detail, and demonstrates its power through application to samples from patients with chronic kidney disease, finding not only known markers of the disease but many previously unknown protein biomarkers.

Today, single protein biomarkers are the foundation of clinical diagnostics: but both normal and disease biology is far more complex than a single measurement can capture: We need to look at multiple biomarkers, or a signature of proteins, that is truly revealing about health and disease at that moment, said Steve Williams, Chief Medical Officer of SomaLogic. The SOMAmer technology empowers us for the first time to measure real biology in a clinically meaningful way.

In the second PLoS One paper, SomaLogic researchers and their collaborators at multiple sites describe the application of SOMAmers at large scale, uncovering a panel of biomarkers that announce the presence of lung cancer. Lung cancer is the leading cause of cancer deaths, mostly because it is detected under current technologies only at its latest stages. By applying SOMAmer technology to over 1300 clinical samples, the researchers rapidly identified a panel or signature of 12 proteins that together accurately reveal the presence of lung cancer in at-risk patients (e.g., long-term smokers). This finding is the basis for a new diagnostic test under development for clinical application in the next year.

By being able to detect lung cancer early, we fi
'/>"/>

Contact: Jeff Walker
jwalker@somalogic.com
303-625-9021
SomaLogic, Inc.
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers describe first functioning lipidome of mouse macrophage
2. Researchers find link between sugar, diabetes and aggression
3. Snakes on a rope: Researchers take a unique look at the climbing abilities of boa constrictors
4. Researchers kick-start ancient DNA
5. Gene links to anorexia found by Childrens Hospital of Philadelphia researchers
6. UGA researchers identify key enzyme that regulates the early growth of breast cancer cells
7. Researchers insert identification codes into mouse embryos
8. Researchers learn that genetics determine winter vitamin D status
9. Researchers link an African lizard fossil in Africa with the Komodo dragon in Indonesia
10. FSU researchers helping K-12 teachers bring science down to Earth
11. As Arctic temperatures rise, tundra fires increase, researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... a biometric authentication company focused on the growing mobile ... and security consultant, Apollo Robbins for the ... wallet.  Apollo Robbins will ... th , 2015, demonstrating some of his famous theft ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... of the "Micro Market Monitor: North America Perimeter ... http://photos.prnewswire.com/prnh/20130307/600769 The ... at a CAGR of 3.6% from 2014 to 2019. ... this market, Canada is expected ...
(Date:12/17/2014)... , Dec. 15, 2014 The Defense ... it easier to detect and prevent counterfeit microcircuits ... Today the agency started performing an in-house microcircuit ... validate the authenticity of purchased microcircuits while increasing ... quality control measures will be conducted at DLA,s ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
... out at the University of Gothenburg may lead to more ... resistant plants, and crops with a limited absorption and storage ... organs in the human body, it is used in the ... active component of drugs against parasitic diseases. Healing ...
... 25, 2012The tiniest and the heaviest fetuses are at much ... new research has found. , Fetuses who are "severely small ... of all fetuses, disproportionately account for about six per cent ... , Fetuses that are "severely large for gestational age," or ...
... The human gut is home to a teeming ecosystem ... and disease. But while the gut microbiota is interacting ... viruses. In a study published online in ... system, revealing a common set of viruses associated with gut ...
Cached Biology News:Arsenic for better drugs and cleaner crops 2Smallest and largest fetuses at greater risk of being stillborn, research finds 2Gut microbes battle a common set of viruses shared by global populations 2
(Date:12/24/2014)... Texas , Dec. 23, 2014 ... company focused on gynecologic disease, announced today that ... Schuler , Birchview Fund LLC and several Vermillion ... of unregistered shares of Vermillion,s common stock and ... stock in a private placement.  ...
(Date:12/24/2014)... , Dec. 23, 2014  Rock Creek Pharmaceuticals, Inc., ... has filed a Clinical Trial Application (CTA) with the ... Regulatory Agency (MHRA) seeking regulatory approval to initiate clinical ... Anatabine Citrate. Contingent on the Company receiving ... Phase I trial to assess the safety, tolerability and ...
(Date:12/22/2014)... Md. , Dec. 22, 2014 /PRNewswire/ ... SYN), a developer of pathogen-specific therapies for ... on protecting the microbiome, today announced positive ... Phase 1a clinical trial of SYN-004, the ... prevention of Clostridium difficile (C. difficile) ...
(Date:12/22/2014)... DIEGO , Dec. 22, 2014 GenomeDx ... the Decipher Prostate Cancer Classifier, a genomic test for ... in node-negative, high-risk men managed by radical prostatectomy without ... radical prostatectomy is relatively uncommon, using tumor genomics to ... of metastatic disease is an important advance. The study ...
Breaking Biology Technology:Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3
... the Cingular merger with AT&T? , ,I've read the business ... acquires the assets and customers of AT&T Wireless for $41 ... No. 2 carrier Verizon by 9 million subscribers. The one ... Wireless brand and plans to launch a new wireless service ...
... movers will get a crash course in getting their foot ... Symposium on March 2 in the Fluno Center. , ... and produced in conjunction with WTN Media, will bring ... , ,I think its quite significant to CIOs, in terms ...
... U.S. during 2004. , ,We also took a look at ... well as how the life science industry performed. Though I had ... life science industry in the Midwest performed, that data is not ... was able to ferret out some additional data on venture capital ...
Cached Biology Technology:Cingular confusion 2Cingular confusion 3Fusion 2005 symposium aims to bring CIOs to the boardroom 2Midwest VC investment up in 2004, but number of deals down 2Midwest VC investment up in 2004, but number of deals down 3
Mouse monoclonal antibody raised against a partial recombinant PDE2A. NCBI Entrez Gene ID = PDE2A...
... array sample elements. , , ,Includes: , , ... in PBS (10X): 50 ml , Streptavidin ... 8 packs , 10% Tween-20: 2 x 10 ... x 25 ml , SuperSignal West Pico Stable Peroxide: ...
... polyclonal antibody raised against a ... Immunogen: XAGE2 (NP_570133, ... partial recombinant protein with GST ... Number: NM_130777 ...
...
Biology Products: