Navigation Links
Solving DNA puzzles is overwhelming computer systems, researchers warn
Date:7/15/2013

Imagine millions of jigsaw puzzle pieces scattered across a football field, with too few people and too little time available to assemble the picture.

Scientists in the new but fast-growing field of computational genomics are facing a similar dilemma. In recent decades, these researchers have begun to assemble the chemical blueprints of the DNA found in humans, animals, plants and microbes, unlocking a door that will likely lead to better healthcare and greatly expanded life-science knowledge. But a major obstacle now threatens the speedy movement of DNA's secrets into research labs, two scholars in the field are warning.

This logjam has occurred, the researchers say, because the flood of unassembled genetic data is being produced much faster than current computers can turn it into useful information. That's the premise of a new article, co-written by a Johns Hopkins bioinformatics expert and published in the July 2013 issue of IEEE Spectrum. The piece, titled "DNA and the Data Deluge," was co-authored by Michael C. Schatz, an assistant professor of quantitative biology at Cold Spring Harbor Laboratory, in New York state; and Ben Langmead, an assistant professor of computer science in Johns Hopkins' Whiting School of Engineering.

In their article, the authors trace the rapidly increasing speed and declining cost of machines called DNA sequencers, which chop extremely long strands of biochemical components into more manageable small segments. But, the authors point out, these sequencers do not yield important biological information that researchers "can read like a book."

Instead, the article says, the sequencing machines "generate something like an enormous stack of shredded newspapers, without any organization of the fragments. The stack is far too large to deal with manually, so the problem of sifting through all the fragments is delegated to computer programs."

In other words, the sequencers produce the ge
'/>"/>

Contact: Phil Sneiderman
prs@jhu.edu
443-287-9960
Johns Hopkins University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Solving electron transfer
2. Researchers analyse rock dissolving method of geoengineering
3. Solving puzzles without a picture
4. Solving stem cell mysteries
5. Solving the stink from sewers
6. Are methane hydrates dissolving?
7. Daydreaming simulated by computer model
8. Computer modeling technique goes viral at Brandeis
9. Computer simulations yield clues to how cells interact with surroundings
10. Computer model may help athletes and soldiers avoid brain damage and concussions
11. Computer modeling reveals how surprisingly potent hepatitis C drug works
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... to ignore, but they are the ultimate source of ... are increasingly dependent on algae, too, to suck up ... to the bottom of the ocean. Now, by using ... have evidence showing that viruses infecting those algae are ... when all else stays essentially the same, and this ...
(Date:8/21/2014)... MELBOURNE, Fla. , Aug. 21, 2014 ...  announced that it has agreed to a ... Orlando,s fastest growing Certified ... make  Gabriel Health Institute  an exclusive member ... a result, Binary Biometrics will improve its ...
(Date:8/21/2014)... from Beth Israel Deaconess Medical Center (BIDMC ) are ... Influential Scientific Minds 2014," a comprehensive list ... resource for science metrics and research performance analysis. ... influential "are performing and publishing work that their peers ... according to a Thomson Reuters statement. Researchers were identified ...
Breaking Biology News(10 mins):Viruses take down massive algal blooms, with big implications for climate 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3BIDMC researchers named among 'the most influential scientific minds' 2BIDMC researchers named among 'the most influential scientific minds' 3
... spiders, and other venomous creatures, the "business end," or active ... of a protein that is most likely to undergo rapid ... Gurion University in Israel. Understanding these evolutionary forces can help ... and may also aid in the design of novel synthetic ...
... world, allocating limited health care resources as effectively and ... address that need, systems engineers at the Georgia Institute ... nations improve supply chain decisions related to the distribution ... are also forecasting what health care services would be ...
... Extensive ongoing research on biotic invasions around the world ... research in the United States shows how using improved ... plant species changes the understanding of patterns of species ... was published in the open access journal ...
Cached Biology News:Molding the business end of neurotoxins 2Engineers improve allocation of limited health care resources in resource-poor nations 2Engineers improve allocation of limited health care resources in resource-poor nations 3Human population the primary factor in exotic plant invasions in the United States 2
(Date:8/22/2014)... New York (PRWEB) August 22, 2014 ... one of the interesting and challenging endeavors as ... renders highly impervious properties to the foreign substances. ... as possibility of self medication and minimal use ... low molecular weight drugs and provides specific targeting ...
(Date:8/22/2014)... 2014 The AMA is pleased to ... in Alaska that Alaska Governor Sean Parnell has signed ... defining public use of Unmanned Aircraft Systems and the ... Bill 255states that it is, “An Act relating to ... an unmanned aircraft system.” It defines State of Alaska ...
(Date:8/21/2014)... Aug. 21, 2014  BioSpecifics Technologies Corp. (NASDAQ: ... first in class collagenase-based products marketed as XIAFLEX ... the U.S. and XIAPEX ® in the ... a randomized, double-blind Phase 2a study of CCH ... fibrosclerotic panniculopathy. The results showed that all three ...
(Date:8/21/2014)... 21, 2014 2014 Deep ... is a professional and in-depth research report ... provides basic Seaweed Fertilizer information, including Seaweed ... structure as well as industry overview. This ... domestic market as well as global industry ...
Breaking Biology Technology:Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 4State of Alaska Signs Unmanned Aircraft Systems Bill 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 3
... ... -, SOUTH ... of a recent Harris,Interactive(R) survey, showing that an overwhelming majority of Tracleer,patients ... their knowledge of pulmonary arterial hypertension (PAH) and,Tracleer have improved due to ...
... /PRNewswire-FirstCall/ - Helix BioPharma Corp.,(TSX, FSE: "HBP") today announced financial results ... HIGHLIGHTS ---------- - Subsequent to the ... CDN$16.9 million private placement of common shares, subject to ... with Dr. Donald H. Segal remaining the ...
... 17 IRIDEX,Corporation (Nasdaq: IRIX ) today ... Company as Chief Financial Officer effective January 2, ... Officer and Vice President,of Finance for NextHop Technologies, ... as Vice President of Finance and Chief,Financial Officer ...
Cached Biology Technology:Survey of More than 600 Patients Treated with Tracleer(R) (bosentan) Reveals Actelion Sure Steps(R) Patient Support Program Provides Valuable Educational Information 2Survey of More than 600 Patients Treated with Tracleer(R) (bosentan) Reveals Actelion Sure Steps(R) Patient Support Program Provides Valuable Educational Information 3Survey of More than 600 Patients Treated with Tracleer(R) (bosentan) Reveals Actelion Sure Steps(R) Patient Support Program Provides Valuable Educational Information 4Helix BioPharma announces Q1 2008 financial results 2Helix BioPharma announces Q1 2008 financial results 3Helix BioPharma announces Q1 2008 financial results 4Helix BioPharma announces Q1 2008 financial results 5Helix BioPharma announces Q1 2008 financial results 6Helix BioPharma announces Q1 2008 financial results 7Helix BioPharma announces Q1 2008 financial results 8Helix BioPharma announces Q1 2008 financial results 9Helix BioPharma announces Q1 2008 financial results 10Helix BioPharma announces Q1 2008 financial results 11IRIDEX Announces James Mackaness Will Be Chief Financial Officer 2
... The CHEMICON APO-BRDU Kit is ... labeling DNA breaks and total cellular DNA ... The kit contains the instructions and ... including; positive and negative control cells for ...
... overlay agarose, is a low melting point ... to secure IPG strips in place for ... incorporated to allow monitoring of electrophoresis runs. ... melting point agarose in 1x Tris, glycine, ...
... cell is an apparatus dedicated to general ... agarose slab gels. The cell includes the ... tray, 5 glass plates, 50 sheets of ... templates, and instructions. Dimensions are 21 x ...
... range of next-generation features into a small-footprint ... for flexible laboratory solutions. It puts every ... dilution, dispensing, and integrations into a ... flexible as it is efficient and economical. ...
Biology Products: