Navigation Links
Software developed by Boston College lab delivers speed and accuracy to genome research
Date:3/27/2008

CHESTNUT HILL, MA It took a global corps of scientists approximately $500 million and 13 years to identify the more than 35,000 genes of the human genome. Five years later, Boston College Biologist Gabor Marth and his research team have developed software that can analyze half a million DNA sequences in 10 minutes.

The Marth laboratorys proprietary PyroBayes software is one of a new breed of computer programs able to accurately process the mountains of genome data flowing from the latest generation of gene decoding machines, which have placed a premium on computational speed and accuracy in data-crunching fields known as bioinformatics and high-throughput biology, said Marth, an associate professor of Biology.

Were on the edge of a real technological revolution that I think will help us understand the genetic causes of diseases in humans and how genetic materials determine traits in animals, said Marth. It is going to lead to less expensive technologies that will allow researchers to decode any individual.

PyroBayes will aid researchers involved in the 1,000 Genomes Project, which announced last month a plan to sequence the genomes of 1,000 individuals from around the world. The NIH, which helps direct the project, has awarded Marth more than $1.3 million to develop software over the next four years.

The advances of the Marth lab were revealed in two articles published by the professor and his assistants in the February issue of Nature Methods, the premier journal of scientific research methodology.

In an article co-authored by Marth, post-doctoral researcher Chip Stewart, and graduate students Aaron Quinlan and Mike Strmberg, the group unveiled the labs PyroBayes base caller software, which examines data from one of the latest generation of DNA decoding machines from Roche / 454 Life Sciences faster and with far greater accuracy than other programs for pyrosequencing, a technology that utilizes the detection of
'/>"/>

Contact: Ed Hayward
ed.hayward@bc.edu
617-552-4826
Boston College
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Futronic Announces Microsoft Vista and Windows 2008 Server Support for Its Fingerprint Logon Software
2. M2SYS Introduces Revolutionary Biometric Artificial Intelligence Technology to Significantly Reduce Fingerprint Software False Reject Rates
3. LOGICARE Selects M2SYS Biometric Fingerprint Software to Ensure Patient Privacy and Protect Confidential Information
4. Software Techniques Inc. Selects M2SYS Fingerprint Software to Meet Continuous Growth and Demand for Desktop Biometric Time & Attendance Solutions
5. Titanium Group Signs Letter of Intent to Acquire Multimilion Dollar Medical Software Company and Its Existing Sales Network
6. Titanium Group Signs Letter of Intent to Acquire Multimilion Dollar Medical Software Company and Its Existing Sales Network
7. CIC Again Named to Software Magazines Annual Prestigious Software 500 List
8. Aware, Inc. Introduces Biometrics Software for Tenprint Autocapture
9. Radiant Systems Selects BIO-key(R) Biometric Software for POS Solution
10. IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks
11. IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... at UTSouthwestern Medical Center have found that the most ... apoE3, helps repair the lining of blood vessels. Individuals ... benefit of this repair, putting them at higher risk ... identified one mechanism by which apoE3 promotes a healthy ... detrimental," said Dr. Philip Shaul , Professor of ...
(Date:9/17/2014)... social behavior by studying nonhuman mammals and primates, but ... their unusually large brains relative to their body size ... environment---not merely in a large population of cooperating creatures, ... setting of alliances and competitors. The same is true ... social carnivores, like hyenas and lions. , A new ...
(Date:9/16/2014)... (17 September, 2014)More than $100 trillion in cumulative ... annual carbon dioxide (CO2)a 40 percent reduction of ... if the world expands public transportation, walking and ... released by the University of California, Davis, and ... , Further, an estimated 1.4 million early ...
Breaking Biology News(10 mins):Protein variant may boost cardiovascular risk by hindering blood vessel repair 2Being social: Learning from the behavior of birds 2Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 2Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 3Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 4Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 5
... While researching methods to increase the already well-recognized ... Illinois also found a way to prolong the vegetable,s ... study, the method is a natural and inexpensive way ... and won,t spoil so quickly on your refrigerator shelf. ...
... disease is the most common form of birth defect, ... the National Institutes of Health. Researchers from the University ... treat laboratory mice with one form of congenital heart ... caused by abnormally thick muscle. By suppressing a faulty ...
... vegetables are associated with higher Body Mass Index (BMI) ... to American University researchers in the journal Pediatric ... between the prices of fruit and vegetables and higher ... and assistant professor of public administration and policy at ...
Cached Biology News:Better broccoli, enhanced anti-cancer benefits with longer shelf life 2Better broccoli, enhanced anti-cancer benefits with longer shelf life 3Compound improves cardiac function in mice with genetic heart defect, MU study finds 2High cost of fruits, vegetables linked to higher body fat in young children 2
(Date:9/18/2014)... -- Neogen Corporation (Nasdaq: NEOG ) announced today ... Merck Animal Health to market Neogen,s Igenity ® ... Heifer Program consists of genomic tests that offer commercial ... replacement dairy heifers. The genomic tests can be performed ... excellent tool in the decision-making process for breeding and ...
(Date:9/18/2014)... September 18, 2014 SeqLL Inc., ... (tSMS™) technology, announced today the closing of a ... led by Genomic Diagnostic Technologies, will increase the ... applications. , Founded in March 2013 by Daniel ... Analyst at Helicos BioSciences, SeqLL has continued to ...
(Date:9/18/2014)... course of a day - car, phone, computer, ... chemical industry to turn raw materials such as ... chemicals that are the ingredients of life,s essential ... achieved outstanding progress in driving this energy intensive ... instead of fossil fuels, has won the prestigious ...
(Date:9/18/2014)... Whitehouse Laboratories is pleased to announce that ... has acquired an additional 4,000 square feet of dedicated ... adjacent to its current package testing facility. The official ... Whitehouse Labs is in the process of upgrading the ... testing. The prime location enables Whitehouse Labs to immediately ...
Breaking Biology Technology:Merck Animal Health to market Neogen's dairy genomic program 2SeqLL Closes Series-A Funding Round for Expansion of Single Molecule Sequencing 2Using solar energy to turn raw materials into ingredients for every day life 2Whitehouse Labs Announces Package Testing Laboratory Expansion 2Whitehouse Labs Announces Package Testing Laboratory Expansion 3Whitehouse Labs Announces Package Testing Laboratory Expansion 4
... in Medical Imaging Management , For Hospitals, Clinics ... 4 Optimal Reading Services Group, Inc., a US-based, ... imaging centers and radiology groups, announced today that the ... investment in Optimal. The investment provides Optimal with funds ...
... LAVAL, QC, June 4 /PRNewswire-FirstCall/ - Neptune Technologies & ... it has signed an agreement with Bayer Healthcare, LLC ... United States. , "The signing of this agreement with ... business and scientific choice to pursue the more demanding ...
... Reported by Roche at 69th Scientific Sessions , ... (Nasdaq: VIAP ), a biotechnology company focused ... cardiovascular and metabolic disease, announced today that preclinical data ... will be presented in a poster presentation at the ...
Cached Biology Technology:Optimal Reading Services Group, Inc. Receives Investment from Health Evolution Partners 2Optimal Reading Services Group, Inc. Receives Investment from Health Evolution Partners 3Neptune Products to be commercialized by BAYER HealthCare 2Neptune Products to be commercialized by BAYER HealthCare 3VIA Pharmaceuticals' DGAT1 Inhibitors Featured in American Diabetes Association Poster Presentation 2VIA Pharmaceuticals' DGAT1 Inhibitors Featured in American Diabetes Association Poster Presentation 3VIA Pharmaceuticals' DGAT1 Inhibitors Featured in American Diabetes Association Poster Presentation 4
TXNL2 Antibody...
Mouse monoclonal [3F8 ] to smooth muscle Myosin heavy chain I ( Abpromise for all tested applications). entrezGeneID: 4629 SwissProtID: P35749...
Request Info...
Goat polyclonal to SART1 ( Abpromise for all tested applications). Antigen: Synthetic peptide: GSSKKHRGEKEAA, corresponding to N terminal amino acids 2-14 of Human SART1. Entrez Gene ID: 909...
Biology Products: