Navigation Links
Sociological research shows combined impact of genetics, social factors on delinquency
Date:7/14/2008

CHAPEL HILL, NC In one of the first studies to link molecular genetic variants to adolescent delinquency, sociological research published in the August issue of the American Sociological Review identifies three genetic predictorsof serious and violent delinquencythat gain predictive precision when considered together with social influences, such as family, friends and school processes.

Sociologists from the University of North Carolina-Chapel Hill explored the interaction of genetics and social influences and identified three genetic polymorphisms thatwhen examined in the context of modulating social controlsare significant predictors of delinquency. These findings about geneenvironment interactions suggest that certain genotypes and specific social control influences (e.g., family characteristics and processes; popularity and friendship characteristics; and school attendance factors) are mutually dependent on delinquency.

While many behavioral studies of geneenvironment interactions typically examine the relationship of a single factor (e.g., child abuse, stress) to genes, the present research is unique in that it systematically examines layers of social context simultaneously (i.e., family dynamics, peer relations, and school-related variables). The study uses regression analysis to reveal non-intuitive and complex relations among the researched variables.

"While genetics appear to influence delinquency, social influences such as family, friends and school seem to impact the expression of certain genetic variants," said Guang Guo, the study's lead author and a professor of sociology and faculty fellow at the University of North Carolina-Chapel Hill's Carolina Population Center and Carolina Center for Genomic Sciences. "Positive social influences appear to reduce the delinquency-increasing effect of a genetic variant, whereas the effect of these genetic variants is amplified in the absence of social controls."

"Our research confirms that genetic effects are not deterministic," Guo said. "Gene expression may depend heavily on the environment."

The three genetic polymorphisms that predict delinquency include: (1) the 30-base pair (bp) promoter-region with a variable number tandem repeat (VNTR) in the monoamine oxidase A (MAOA) gene, (2) the 40-bp VNTR in the dopamine transporter 1 (DAT1) gene and (3) the Taq1 polymorphism in the dopamine D2 receptor (DRD2) gene. MAOA regulates several brain neurotransmitters important in behavioral motivation, aggression, emotion and cognition (e.g., serotonin, dopamine, norepinephrine).

Among the findings, the research suggests a conditional interaction between repeating a school grade and the MAOA*2 repeat (2R) allele in adolescent boys. For those who did not have the 2R allele, repeating a grade was significantly correlated with serious delinquency, but for those who had this 2R allele and who repeated a grade, the propensity for serious delinquency increased dramatically.

The study also indicates a link between the DRD2 gene and having daily family meals. Daily meals with one or two parents are a powerful moderator for the effect of the DRD2 gene.

"Most delinquent and violent behaviors are considered complex," Guo said. "Understanding these behaviors requires understanding both their socioeconomic-cultural components and their genetic components."

The correlation of social and genetic effects on delinquency suggests the need for the social sciences to incorporate genetic evidence in this area of study, according to Guo. The implications of these findings also raise important questions for public policy.


'/>"/>

Contact: Jackie Cooper
jcooper@asanet.org
202-247-9871
American Sociological Association
Source:Eurekalert

Related biology news :

1. Louisiana Tech researchers feature drug reformulation in prestigious journal
2. UCLA researchers locate and image prostate cancer as it spreads to lymph nodes
3. UCSB researcher leads worldwide study on marine fossil diversity
4. National Institutes of Health award Williams professor $217,710 research grant
5. Charcot-marie-tooth disease research funding
6. Glenn Foundation for Medical Research commits $5 million to study aging
7. Researchers catch ion channels in their opening act
8. UGA researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes
9. Researchers hack final part of the immune system code
10. Revolutionary chefs? Not likely, shows physics research
11. Scripps research scientists reveal key structure from ebola virus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... YORK , June 2, 2016   The Weather ... is announcing Watson Ads, an industry-first capability in which consumers ... by being able to ask questions via voice or text ... Marketers have long sought ... the consumer, that can be personal, relevant and valuable; and ...
(Date:6/1/2016)... June 1, 2016 Favorable Government ... Administration and Criminal Identification to Boost Global Biometrics System ... released TechSci Research report, " Global Biometrics Market ... Forecast and Opportunities, 2011 - 2021", the global biometrics ... 2021, on account of growing security concerns across various ...
(Date:5/20/2016)... May 20, 2016  VoiceIt is excited to ... VoicePass. By working together, VoiceIt and ... VoiceIt and VoicePass take slightly different approaches to ... both security and usability. ... this new partnership. "This marketing and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , ... June 23, 2016 , ... ... pleased to announce the launch of their brand, UP4™ Probiotics, into Target stores ... 35 years, is proud to add Target to its list of well-respected retailers. ...
(Date:6/23/2016)... 23, 2016 A person commits a crime, and ... to track the criminal down. An outbreak of ... Drug Administration (FDA) uses DNA evidence to track down the ... Sound far-fetched? It,s not. The FDA has increasingly used a ... of foodborne illnesses. Put as simply as possible, whole genome ...
(Date:6/23/2016)... MONICA, Calif. , June 23, 2016  The Prostate Cancer Foundation ... pioneer increasingly precise treatments and faster cures for prostate cancer. Members of the ... institutions across 15 countries. Read More About the Class ... ... ...
(Date:6/23/2016)... ... 2016 , ... Supplyframe, the Industry Network for electronics hardware ... . Located in Pasadena, Calif., the Design Lab’s mission is to bring together ... built and brought to market. , The Design Lab is Supplyframe’s physical representation ...
Breaking Biology Technology: