Navigation Links
Social scientists study impact of human adult stem cell research
Date:6/10/2011

New research says studying both adult and embryonic stem cells can benefit medical science, but banning the study of either type could harm studies of the other.

Researchers from the University of Michigan, Stanford University and the Mayo Clinic in Rochester, Minn. recently investigated whether the increased number of studies with a certain type of adult stem cell has changed the overall course of research in the field.

The researchers analyzed more than 2,000 scientific papers and found adult stem cells are not replacing human embryonic stems cells in the laboratory. Instead, the two cell types have proven to be complementary and any disruption of federal funding, they say, would negatively impact stem cell research overall.

"This is an important study that systematically examines the co-authorship networks of stem cell research articles and uses those to understand the interactions between two complementary areas of research," says Julia Lane, program director for Science of Science & Innovation Policy at the National Science Foundation (NSF), which funded the study.

"It is particularly interesting because it uses new analytical techniques to advance our understanding of how the implementation of policy in one area can affect scientific research in another area."

The research appears in the June 9 journal Cell.

"The incentives to use both types of cell in comparative studies are high," says Jason Owen-Smith, a sociologist at University of Michigan. He notes the science behind adult stem cells that can be "reprogrammed," called human induced pluripotent stem cells (hiPSCs), is still in its infancy, having become widely available in 2007.

"As a result, induced pluripotent stem cells do not offer an easy solution to the difficult ethical questions surrounding embryonic stem cell research," he says.

Pluripotent stem cells are those capable of differentiating into any type of tissue, hence the attractiveness of embryonic stem cells, or hESCs, also called ES cells, which are also pluripotent.

The researchers examined stem cell research papers published between 1998 and 2010. They found the proportion of papers using human adult and human embryonic stem cells together is growing faster than those using adult stem cells alone.

In 2008, only 15 or 5.1 percent of all papers examined in the study reported using adult stem cells, and only three of those papers combined the use of human adult and human embryonic stem cells. By 2010, some 161 of 574 or 28 percent of papers reported on studies of both cell technologies, and 62.1 percent of those papers paired adult and embryonic cell lines.

Because use of the two cell types has become so intertwined, any federal policy that would deny funding for embryonic stem cell research "would derail work with a nascent and exciting technology," says Owen-Smith.

If federal funding stops for human embryonic stem cell research, it would have a serious negative impact on adult stem cell research, says Stanford University bioethicist Christopher Scott, one of the paper's co-authors. "We may never be able to choose between iPS and ES cell research because we don't know which type of cell will be best for eventual therapies."

"The whole point with science policy is to have a more scientific basis to understand the impacts of policy decisions on science if and when those decisions are made," says Lane


'/>"/>

Contact: Bobbie Mixon
bmixon@nsf.gov
703-292-8485
National Science Foundation
Source:Eurekalert  

Related biology news :

1. New Interdisciplinary Scholar Networks to build better social welfare research
2. USC: Active social, spiritual and physical life helps prevent health decline in seniors
3. Genomics and social network analysis team up to solve disease outbreaks
4. Social network helps in discovery of a species of plant lice for the first time in Europe
5. JAMIA reports on people, their information needs and social networks
6. Can one model the social deficits of autism and schizophrenia in animals?
7. Gulf oil spill similar to Exxon Valdez in initial social and mental impacts, study finds
8. Chimp, bonobo study sheds light on the social brain
9. Tweeting teenage songbirds reveal impact of social cues on learning
10. Seeking social genes
11. Parents social problems affect their children -- even in birds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Social scientists study impact of human adult stem cell research
(Date:2/26/2017)... , Feb. 25, 2017  Securus Technologies, ... technology solutions for public safety, investigation, corrections and ... Recidivism and Reentry. "Too often, too ... prisons and county jails are trying to tackle ... inmates and friends and family members. While significant steps ...
(Date:2/21/2017)... 21, 2017 Der weltweite Biobanking-Sektor ... Nach einem Gespräch mit mehr als 50 Vertretern aus verschiedenen ... überwinden gilt, um diese Prognose zu realisieren. ... Zu ... der finanziellen Mittel für die Biobank, die Implementierung Zeit ...
(Date:2/13/2017)... , Feb. 13, 2017 Former 9/11 Commission ... Judiciary Committee, Janice Kephart of Identity Strategy ... Donald Trump,s "Executive Order: Protecting the Nation ... 27, 2017):  "As President Trump,s ,Travel Ban, ... has now essentially banned the travel ban, it is ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... , March 27, 2017 Infectex Ltd., a Russian portfolio ... 2b-3 clinical study of SQ109 added to the standard drug therapy regimen in patients ... scientists at Sequella, Inc. ( USA ) and the US National Institutes ... ... Maxwell Biotech Venture Fund Logo ...
(Date:3/27/2017)... , ... March 27, 2017 , ... ... to engineer scalable and customizable vascular grafts in JoVE’s Video Journal, the world’s ... to new and improved ways of treating coronary artery disease (CAD). Lam is ...
(Date:3/24/2017)... ROCKVILLE, Md. , March 24, 2017 ... Biotech Venture Fund (MBVF), today announced positive results of ... the standard drug therapy regimen in patients with multidrug-resistant ... drug discovered by scientists at Sequella, Inc. ( ... Health. A total of 140 patients ...
(Date:3/24/2017)... Mass. , March 24, 2017 Agenus ... of immune checkpoint antibodies and cancer vaccines, today announced ... The 7 th  Annual William Blair and Maidstone Life ... Space Alexandria Center in New York, NY ... March 29 at 9:40 am: Robert ...
Breaking Biology Technology: