Navigation Links
Social scientists study impact of human adult stem cell research
Date:6/10/2011

New research says studying both adult and embryonic stem cells can benefit medical science, but banning the study of either type could harm studies of the other.

Researchers from the University of Michigan, Stanford University and the Mayo Clinic in Rochester, Minn. recently investigated whether the increased number of studies with a certain type of adult stem cell has changed the overall course of research in the field.

The researchers analyzed more than 2,000 scientific papers and found adult stem cells are not replacing human embryonic stems cells in the laboratory. Instead, the two cell types have proven to be complementary and any disruption of federal funding, they say, would negatively impact stem cell research overall.

"This is an important study that systematically examines the co-authorship networks of stem cell research articles and uses those to understand the interactions between two complementary areas of research," says Julia Lane, program director for Science of Science & Innovation Policy at the National Science Foundation (NSF), which funded the study.

"It is particularly interesting because it uses new analytical techniques to advance our understanding of how the implementation of policy in one area can affect scientific research in another area."

The research appears in the June 9 journal Cell.

"The incentives to use both types of cell in comparative studies are high," says Jason Owen-Smith, a sociologist at University of Michigan. He notes the science behind adult stem cells that can be "reprogrammed," called human induced pluripotent stem cells (hiPSCs), is still in its infancy, having become widely available in 2007.

"As a result, induced pluripotent stem cells do not offer an easy solution to the difficult ethical questions surrounding embryonic stem cell research," he says.

Pluripotent stem cells are those capable of differentiating into any type of tissue, hence the attractiveness of embryonic stem cells, or hESCs, also called ES cells, which are also pluripotent.

The researchers examined stem cell research papers published between 1998 and 2010. They found the proportion of papers using human adult and human embryonic stem cells together is growing faster than those using adult stem cells alone.

In 2008, only 15 or 5.1 percent of all papers examined in the study reported using adult stem cells, and only three of those papers combined the use of human adult and human embryonic stem cells. By 2010, some 161 of 574 or 28 percent of papers reported on studies of both cell technologies, and 62.1 percent of those papers paired adult and embryonic cell lines.

Because use of the two cell types has become so intertwined, any federal policy that would deny funding for embryonic stem cell research "would derail work with a nascent and exciting technology," says Owen-Smith.

If federal funding stops for human embryonic stem cell research, it would have a serious negative impact on adult stem cell research, says Stanford University bioethicist Christopher Scott, one of the paper's co-authors. "We may never be able to choose between iPS and ES cell research because we don't know which type of cell will be best for eventual therapies."

"The whole point with science policy is to have a more scientific basis to understand the impacts of policy decisions on science if and when those decisions are made," says Lane


'/>"/>

Contact: Bobbie Mixon
bmixon@nsf.gov
703-292-8485
National Science Foundation
Source:Eurekalert  

Related biology news :

1. New Interdisciplinary Scholar Networks to build better social welfare research
2. USC: Active social, spiritual and physical life helps prevent health decline in seniors
3. Genomics and social network analysis team up to solve disease outbreaks
4. Social network helps in discovery of a species of plant lice for the first time in Europe
5. JAMIA reports on people, their information needs and social networks
6. Can one model the social deficits of autism and schizophrenia in animals?
7. Gulf oil spill similar to Exxon Valdez in initial social and mental impacts, study finds
8. Chimp, bonobo study sheds light on the social brain
9. Tweeting teenage songbirds reveal impact of social cues on learning
10. Seeking social genes
11. Parents social problems affect their children -- even in birds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Social scientists study impact of human adult stem cell research
(Date:4/15/2016)... , April 15, 2016  A new ... make more accurate underwriting decisions in a fraction ... timely, competitively priced and high-value life insurance policies ... screenings. With Force Diagnostics, rapid testing ... lifestyle data readings (blood pressure, weight, pulse, BMI, ...
(Date:3/31/2016)...  Genomics firm Nabsys has completed a financial  restructuring ... , M.D., who returned to the company in October ... team, including Chief Technology Officer, John Oliver , ... and Vice President of Software and Informatics, Michael ... Dr. Bready served as CEO of Nabsys from 2005-2014 ...
(Date:3/21/2016)... March 22, 2016 Unique ... passcodes for superior security   ... provider of secure digital communications services, today announced it ... and offer enterprise customers, particularly those in the Financial ... and voice authentication within a mobile app, alongside, and ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... NY (PRWEB) , ... April 28, 2016 , ... ... has made significant investments in recruiting top industry experts, and expanding its LATAM ... which provides industry-leading tools for clients to manage their clinical trial projects. , ...
(Date:4/27/2016)... ... April 27, 2016 , ... Cambridge Semantics, ... web technology, today announced that it has been named to The Silicon Review’s “20 ... services and other markets, Cambridge Semantics serves the needs of end users facing some ...
(Date:4/27/2016)... ... ... Pittcon Organizing Committee is pleased to announce that Charles “Chuck” Gardner was named president ... Since then, he has served in a number of key leadership positions including secretary ... and exposition committees. In his professional career, Dr. Gardner is the director of product ...
(Date:4/27/2016)... VANCOUVER, British Columbia , April 27, 2016 ... "Gesellschaft" oder "NanoStruck") (CSE: NSK) (OTCPink: NSKQB) ( ... sie im Anschluss an ihre Pressemitteilung vom 13. ... Inc. erhalten hat, ihre Finanzen um zusätzliche 200.000.000 ... auf 4.000.000 Kanadische Dollar zu bringen. Davon wurden ...
Breaking Biology Technology: