Navigation Links
'Snooze button' on biological clocks improves cell adaptability
Date:2/17/2013

k down in the algae, but it did have a more subtle, but potentially as profound effect: It significantly reduced cell survival at certain temperatures.

"Xu figured that the biological clock with optimized codons might work better at lower temperatures and it did," Johnson said. However the substitution also modified the biological clock so it ran with a longer, 30-hour period. When forced to operate in a 24-hour daily light/dark cycles, the bacteria with the optimized clock grew significantly slower than "wild-type" cells. "In cyanobacteria, it's as if writing speed changes the meaning," said Rokas.

The potential importance of changes in synonymous codon usage in adapting to environmental factors is magnified by the fact that they can influence the operation of biological clocks, which function as a key adaptation to daily environmental rhythms. Biological clocks control and influence dozens of different basic biological processes, including sleeping and feeding patterns, core body temperature, brain activity, hormone production and cell regeneration.

"It is now clear that variations in codon usage is a fundamental and underappreciated form of gene regulation," said Rokas.

Recognition of the importance of this process has a number of potential applications in biotechnology. For example, "it should be possible to improve the ability of algae to robustly express biofuel-producing proteins from other organisms by optimizing the codons that they use," Johnson said.


'/>"/>

Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Hitting snooze on the molecular clock: Rabies evolves slower in hibernating bats
2. New guide will allow electric utilities to develop Green Button Web tools
3. Unraveling biological networks
4. New method for estimating parameters may boost biological models
5. A project to research biological and chemical aspects of microalgae to fuel approach
6. EPA to highlight innovative ways to detect and respond to biological threats
7. Salk scientists redraw the blueprint of the bodys biological clock
8. Weeding out invasive species with classical biological control
9. Crime and punishment: The neurobiological roots of modern justice
10. Electric charge disorder: A key to biological order?
11. Florida Tech biological sciences professor earns $257,000 NSF grant to study coral diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... Sustainable Global Logistics Operations) is aiming to cut CO2 ... intermodal loading systems and the boosting of intelligent systems ... with experience in the logistics sector and in supply ... a duration of three and a half years. , ... components and ontologies shared by the users, objects and ...
(Date:5/17/2013)... Bethesda, MD The Federation of American Societies for ... of National Institutes of Health (NIH) funding trends highlighting ... to support critical research. The FASEB analysis follows a ... Francis Collins, MD, PhD, who testified that the $1.6 ... to sequestration is "having a substantial impact on the ...
(Date:5/16/2013)... 2013) Illustrating a commitment to the support ... Association (AGA) Research Foundation has announced the inaugural ... Award recipients. Supported by the National Institute of ... new award helps underrepresented minority students to further ... research. , "By establishing this new award, AGA ...
Breaking Biology News(10 mins):New logistics services that will cut energy consumption and CO2 emissions 2Underrepresented minority students receive fellowships in digestive disease and nutrition research 2
... New Orleans, LA Research conducted by Dr. Jayne S. ... Center New Orleans, and colleagues has found that a defect ... cornea also contributes to the progression of invasive bladder cancer. ... the peer-reviewed journal, DNA and Cell Biology . It ...
... November issue of The American Naturalist : ... are sexy How global warming could cause animals to shrink How ... egg could lead to permanent problems For the complete ... . The singer not the song: Why some birds ...
... - An international team of scientists, including biologists from the ... for the first time the mechanism responsible for cell polyploidy, ... sets of chromosomes. When it comes to human chromosomes ... pairs. Bundled within the nucleus of our cells are 46 ...
Cached Biology News:Mutation in gene associated with rare eye disease also contributes to bladder cancer growth 2Why some birds think simple songs are sexy 2Why some birds think simple songs are sexy 3Why some birds think simple songs are sexy 4Growing without cell division 2
(Date:5/17/2013)... 2013 - Elsevier, a world-leading provider of scientific, technical ... publication of a recent study in Reproductive ... showing that those with an abnormal chromosomal composition can ... developed to blastocysts, thereby classifying the risk of genetic ... same group has undertaken a retrospective study, using their ...
(Date:5/17/2013)... USA (PRWEB) May 17, 2013 •    First ... Globes Certified for sustainability ,     New facility will ... , Syngenta unveiled its new ... at the company’s RTP Innovation Center. The first of ... researchers to simulate any agricultural climate and precisely measure ...
(Date:5/17/2013)... May 17, 2013  Cellular Biomedicine Group (OTCQB: ... enrollment of the total projected enrollment required for ... and preliminary efficacy of the medical technology haMPC ... Osteoarthritis (KOA). To date the trial has had ... The Phase I open label clinical research trial ...
(Date:5/17/2013)... SAN JOSE, Calif. , May 17, 2013 ... an agreement has been reached with ... entire portfolio of anti-infective human monoclonal antibody (mAb) ... six anti-infective human mAb products for treatment of ... strains of Staphylococcus aureus , Pseudomonas ...
Breaking Biology Technology:Breakthrough for IVF? 2Breakthrough for IVF? 3Syngenta Opens Unique $72 Million Advanced Crop Lab 2Syngenta Opens Unique $72 Million Advanced Crop Lab 3Cellular Biomedicine Group Achieves 50% Enrollment Milestone in Phase I Clinical Trial for Knee Osteoarthritis 2Aridis Pharmaceuticals Announces Acquisition of Monoclonal Antibody Products and Technologies From Kenta Biotech 2Aridis Pharmaceuticals Announces Acquisition of Monoclonal Antibody Products and Technologies From Kenta Biotech 3
... columns back I mentioned my first law of softwareany mildly ... it is an operating system. Youve seen it. The e-mail ... then helper applications in version three and so on. The ... the poster child for this kind of behavior is the ...
... season, and you've been poked and prodded by television ads, ... Kerry drank a beer at your neighborhood bar and George ... Cheney was spotted more in Wisconsin in 2004 than he ... John Edwards has been in the state so often he's ...
... Norlight Telecommunications , a Brookfield, Wisconsin, telecommunications ... service for small and medium-sized businesses in Wisconsin and ... offer the service to businesses in Minnesota, Michigan, and ... , , IPLive will integrate voice, data and ...
Cached Biology Technology:The first law of software 2The first law of software 3Twenty ways you can tell this campaign has finally pushed you over the edge 2
Dopamine D2 and D3 receptor, human and possibly mouse. AB1502 detects 40 ng of dopamine receptor peptide by ELISA. AB1502 is not neutralizing....
Rabbit polyclonal to SpUlp2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: SNNERQSLSSGSND, corresponding to amino acids 622-635 of Schizosaccharomyces pombe SpUlp2...
STX18 Immunogen: STX18 (NP_058626, 101 a.a. ~ 200 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Request Info...
Biology Products: