Navigation Links
'Snooze button' on biological clocks improves cell adaptability
Date:2/17/2013

The circadian clocks that control and influence dozens of basic biological processes have an unexpected "snooze button" that helps cells adapt to changes in their environment.

A study by Vanderbilt University researchers published online Feb. 17 by the journal Nature provides compelling new evidence that at least some species can alter the way that their biological clocks function by using different "synonyms" that exist in the genetic code.

"This provides organisms with a novel and previously unappreciated mechanism for responding to changes in their environment," said Professor of Biological Sciences Carl Johnson. He and Associate Professor of Biological Sciences Antonis Rokas collaborated on the study.

Like many written languages, the genetic code is filled with synonyms: differently spelled "words" that have the same or very similar meanings. For a long time, biologists thought that these synonyms, called synonymous codons, were in fact interchangeable. Recently, they have realized that this is not the case and that differences in synonymous codon usage have a significant impact on cellular processes, so scientists have advanced a wide variety of ideas about the role that these variations play.

The new insight is not only an important advance in understanding evolution at the molecular level, but it also has potential applications in biotechnology, such as biofuel production, and gene therapy.

"While biological clocks are vital to maintaining healthy patterns of sleep, metabolism, physiology and behavior, under certain environmental conditions strict adherence to these rhythms can be disadvantageous," said Michael Sesma of the National Institute of General Medical Sciences, which partially funded the work. "This work shows how organisms can ignore the clock under certain circumstancesmuch like hitting a biological snooze button on the internal timepieceand enhance their survival in the face of ever-changing circumstances."

The
'/>"/>

Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Hitting snooze on the molecular clock: Rabies evolves slower in hibernating bats
2. New guide will allow electric utilities to develop Green Button Web tools
3. Unraveling biological networks
4. New method for estimating parameters may boost biological models
5. A project to research biological and chemical aspects of microalgae to fuel approach
6. EPA to highlight innovative ways to detect and respond to biological threats
7. Salk scientists redraw the blueprint of the bodys biological clock
8. Weeding out invasive species with classical biological control
9. Crime and punishment: The neurobiological roots of modern justice
10. Electric charge disorder: A key to biological order?
11. Florida Tech biological sciences professor earns $257,000 NSF grant to study coral diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/11/2015)... 11, 2015 Curemark LLC, a privately held ... a new Phase III double blind, randomized, placebo-controlled clinical ... CM-AT, on all children ages 3-8 with Autism. Previously, ... III double blinded clinical trial for CM-AT in children ... the digestive enzyme chymotrypsin. This new trial will help ...
(Date:5/6/2015)... , May 6, 2015 LifeBEAM, a developer ... helmet producer, announced today that they will expand their ... world,s first bio-sensing cycling helmet and the first joint ... two new colors in order to give cyclists more ... In addition, LifeBEAM and Lazer announced their plan to ...
(Date:4/27/2015)... FORT LAUDERDALE, Fla. , Apr. 27, 2015 /PRNewswire/ ... provider of access control and security systems is pleased ... joined the company as a consultant and member of ... Bedore is widely known as a thought leader ... Socrates Distance Learning Technology Group, and has published studies ...
Breaking Biology News(10 mins):Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4
... developers of the fuel-efficient Berkeley-Darfur Stove for refugee camps ... time evaluating inexpensive metal cookstoves for the displaced survivors ... the U.S. Department of Energy,s Lawrence Berkeley National Laboratory ... University of California (UC), Berkeley to run a series ...
... of autism spectrum disorders (ASD) is impairments in ... face difficulty understanding, interacting and relating with others. ... receive more intensive therapy to combat these impairments, ... "It,s important for children with ...
... Energy (PIE) and TomKat Center for Sustainable Energy are ... million for promising new research in renewable energy. ... jumpstart new projects with the potential for high impact ... of energy resources engineering. "These awards will enable ...
Cached Biology News:Berkeley Lab tests cookstoves for Haiti 2Berkeley Lab tests cookstoves for Haiti 3Berkeley Lab tests cookstoves for Haiti 4Children with autism benefit from early, intensive therapy 2Stanford Precourt Institute and TomKat Center award energy research grants 2Stanford Precourt Institute and TomKat Center award energy research grants 3Stanford Precourt Institute and TomKat Center award energy research grants 4Stanford Precourt Institute and TomKat Center award energy research grants 5
(Date:6/2/2015)... 02, 2015 Research and Markets ( http://www.researchandmarkets.com/research/6wjpd6/bioburden_testing ... Testing Market by Product , Test, Application & End ... offering. The bioburden testing market is expected ... in 2014, growing at a CAGR of 9.8% from ... the microbial limit testing market is segmented into consumables ...
(Date:6/2/2015)... , June 2, 2015 ... Inner Emotion Scanner. Scan & Read People. Analyze emotions ... & ART Concepts, including the very first Responsive-RPG: "The ... ) , , , , ... probe and truly affect your inner feelings - and ...
(Date:6/2/2015)... Pa. , June 2, 2015   ... be attending the BIO Exhibition 2015 in ... Exhibition, the world,s largest biotechnology gathering, allows influential ... high-level executives, where they can evaluate emerging technologies ... significant eClinical expertise in the design, implementation and ...
(Date:6/2/2015)... 2015   Sigma-Aldrich Corporation (NASDAQ: SIAL ... announced today it has entered into an agreement ... engineered human neural differentiated cells and accompanying culture ... diseases. These new products, in combination with Sigma-Aldrich,s ... for the study of central nervous system (CNS) ...
Breaking Biology Technology:Bioburden Testing Market 2015 - Global Forecasts to 2019 2ARGUS - The World's First Inner Emotion Scanner Launches on KickStarter 2ARGUS - The World's First Inner Emotion Scanner Launches on KickStarter 3YPrime at BIO Exhibition in Philadelphia and DIA in Washington DC during the month of June 2Sigma-Aldrich to Launch XCell Science Genetically Engineered iPSC-Derived Neural Disease Cells 2Sigma-Aldrich to Launch XCell Science Genetically Engineered iPSC-Derived Neural Disease Cells 3
... pretend to be a fortune teller, but he believes ... standard in radiation therapy for some time to come. ... that the Hi-Art System, the company's radiation therapy platform, ... almost 250,000 patient fractions, or incremental treatments, have been ...
... - The first executive director of The Morgridge Institute ... will be instrumental in shaping its direction and values. ... , ,MIR, the new private, not-for-profit research institute is ... executive director position. The institute's core mission is to ...
... Wis. - Most Wisconsin manufacturers polled in ... raw materials costs and pricing pressures outweigh anxiety ... Extension Partnership , a nonprofit consulting organization for ... 173 Wisconsin firms. They ranked themselves on performance ...
Cached Biology Technology:TomoTherapy sees sustained market advantage 2TomoTherapy sees sustained market advantage 3TomoTherapy sees sustained market advantage 4
... have the durability to run ... and the uniformity and contamination ... applications. Heavily built with ... stackers are designed for ease ...
CQCS kit for first KR 4i , (first unit)....
Multidrop Micro high speed 1 l bulk reagent dispenser rapidly, precisely and accurately dispenses microvolumes of 1-50 l into 384- and 96-well microplates....
MBS 384 well satellite block unit with height adjusting heated lid, 384 well block holds 1 x 0.04 ml 384 well plate...
Biology Products: