Navigation Links
Smell the potassium
Date:7/29/2012

es but "in vivo"in the working VNOs of live micethey found a very different result: On balance the potassium channels now sent potassium ions in the inward direction. In fact, these two newly discovered channels seemed to account for more than half of the VNO-activating current.

This inflowing-potassium phenomenon is known to occur in another type of sensory neuron, the sound-sensitive cochlear hair cell, whose external environment contains relatively high levels of potassium. "This made us wonder whether the VNO also has a high level of potassium in the fluid surrounding its dendrites," says Kim.

It does. It turns out that the standard preparation of tissue slices for the initial patch-clamp experiments had washed away that naturally high concentration. The resulting low concentration had misleadingly caused potassium ions to be sucked out of VNO neuron dendrites when the SK3 and GIRK potassium channels were opened. "It's a cautionary tale that shows the importance of doing in vivo experiments," Yu says.

The finding that potassium channels contribute to the primary activation of the VNO could be a clue to the origins of the organ. "We speculate that the VNO may have evolved to have a high extracellular concentration of ions, as well as multiple ion channels, so that it remains functional even when it comes into contact with various ion-rich bodily fluids," Yu says. "The diversity of signaling pathways perhaps make it more robust in triggering innate behaviors."


'/>"/>
Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Smell and taste experts to discuss new discoveries
2. A trained palate: Understanding complexities of taste, smell could lead to improved diet
3. Mosquitoes -- how we smell is why they bite, research shows
4. Mice have distinct subsystem to handle smell associated with fear
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smell the potassium
(Date:4/10/2015)... 2015 Research and Markets ( ... "Security Competitive Profiles - NEC" report to their ... NEC will continue to supply a range of IT ... a company focus on the development of a Big ... opportunities in the Asia-Pacific region ...
(Date:4/6/2015)... , Apr. 6, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile ... provisional patent 62/143028 for MINIATURE, MULTI-PURPOSE ... TRANSFER  NXT-ID introduces a new revolutionary ... patent surrounds the use of miniature antenna modules ...
(Date:4/2/2015)... April 2, 2015 According to ... attributed to somewhat higher than 125 MSEK. This exceeds ... report 2014 that revenues for Q1 2015 would be ... reported for Q4 2014. The operating result for the ... The complete interim report will as previously communicated be ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4Fingerprint Cards Revises Revenues for Q1 2015 2
... -- Rice University scientists have unveiled a revolutionary new ... into steam. The new "solar steam" method from Rice,s ... even produce steam from icy cold water. Details ... in ACS Nano . The technology has an ...
... after Hurricane Sandy hit, NJIT Professor Michel Boufadel was awarded ... of the storm on the New Jersey shoreline. The ... a team of eight researchers to the beaches of Raritan ... students is still fanning out over the shoreline and ...
... getting, when they select females for mating, according to a ... Wisconsin-Milwaukee in the US. His work, which is one of ... mating behaviors in a nocturnal anuran (frog or toad), is ... . Animals display a number of courtship behaviors and ...
Cached Biology News:Rice unveils super-efficient solar-energy technology 2Rice unveils super-efficient solar-energy technology 3NJIT civil engineer receives NSF grant to study storm's impact on Jersey Shore 2Vision stimulates courtship calls in the grey tree frog 2
(Date:5/6/2015)... 2015  Northwest Biotherapeutics (NASDAQ: NWBO) ("NW Bio"), a U.S. ... cancers, today announced that Linda Powers , NW Bio CEO, ... vaccine platform for solid tumor cancers and the Company,s multiple ...   , , , DATE: , , , ... , , , 12:15 PM EDT , , , ...
(Date:5/6/2015)... May 06, 2015 Park Systems ... NX-Hivac, the only high vacuum AFM system in the ... failure analysis semiconductor manufacturing. Park NX-Hivac is ideal for ... analysis solutions in highly doped semiconductor processing where more ... , The high vacuum scanning spreading resistance microscopy (SSRM) ...
(Date:5/6/2015)... Histogen, Inc., a regenerative medicine company ... grown under simulated embryonic conditions, will present new ... melanoma during the 2015 Society of Investigative Dermatology ... in Atlanta, GA. , Histogen has previously shown ... with anti-oncologic properties, with potential benefit in the ...
(Date:5/6/2015)... 06, 2015 The Remedy Group ... strategy for the specialty pharmacy industry, will be exhibiting, ... Armada Specialty Pharmacy Summit. The Summit will be held ... Vegas and is the largest annual gathering for the ... attendance, from pharmacy providers, pharma/biotech manufacturers, and payers, to ...
Breaking Biology Technology:NW Bio To Webcast, Live, at VirtualInvestorConferences.com On May 7 2NW Bio To Webcast, Live, at VirtualInvestorConferences.com On May 7 3Park Systems Introduces Park NX-Hivac, a High Vacuum SSRM AFM System for Optimal Results in Semiconductor Manufacturing Failure Analysis 2Park Systems Introduces Park NX-Hivac, a High Vacuum SSRM AFM System for Optimal Results in Semiconductor Manufacturing Failure Analysis 3Novel Immunomodulatory Treatment Induces Apoptosis in Melanoma 2The Remedy Group presenting at the 2015 Armada Specialty Pharmacy Summit: The Pitfalls to Growth and Maintaining the Patient Experience 2
... Corp. (TSX: HBP / Frankfurt: WKN 918864), ... Corp.,announces that at the Company,s Annual General Meeting ... the resolutions presented by,management, appointing KPMG LLP as ... Kay, Slawomir Majewski, and Gordon Lickrish as,directors, and ...
... Jan. 30 MiddleBrook,Pharmaceuticals, Inc. (Nasdaq: MBRK ... novel anti-infective products, today,announced that it has closed ... warrants, resulting in the receipt of $21 million ... the proceeds from the financing to support,the manufacture ...
... Jan. 30 /Xinhua-PRNewswire-FirstCall/ --,Kiwa Bio-Tech Products Group Corporation ... bio-enhanced feed products sold during the fourth,quarter of ... and increased,25% over the same period in the ... ("Kiwa Tianjin") is a joint-venture of Kiwa,and Tianjin ...
Cached Biology Technology:Helix BioPharma shareholders vote in favour of management 2MiddleBrook Pharmaceuticals Closes Private Placement of Common Equity Raising $21 Million 2MiddleBrook Pharmaceuticals Closes Private Placement of Common Equity Raising $21 Million 3Kiwa Bio-Tech Animal Feed Volume Increased 25% in Fourth Quarter of 2007 2
Goat polyclonal to Centaurin alpha 2**...
... background ,This solution greatly enhances antigen-antibody reactions, ... obtained with conventional methods. ,Two kinds of ... antibodies, which can suppress the background and ... versatility ,It is applicable to various assay ...
Monocarboxylate (lactate) transporter 2...
Mouse anti human pro-Relaxin-2...
Biology Products: