Navigation Links
'Smart scaffolds' may help heal broken hearts
Date:1/12/2009

Imagine new treatments for heart disease or muscle loss that direct the body to repair damaged tissue rather than helping it cope with a weakened condition. That's not hard to do thanks to Canadian researchers, who for the first time, have developed an organic substance that attracts and supports cells necessary for tissue repair and can be directly injected into problem areas. This development, published online in The FASEB Journal (http://www.fasebj.org) is a major step toward treatments that allow people to more fully recover from injury and disease rather than having to live with chronic health problems. It may even help reduce the need for organ transplantation by allowing physicians to save organs that would have been previously damaged beyond repair.

The "smart scaffolds," developed by Erik Suuronen and his colleagues from the University of Ottawa and the Ottawa Heart Research Institute, work because they contain a protein that allows progenitor cells to adhere to the damaged tissue and survive long enough to promote healing. These cells emit homing signals that summon other cells to join in the process and give off chemical signals that order cells to grow blood vessels necessary for healing to occur.

"Ultimately, we envision a scaffold material that can be taken off the shelf and injected into the hearts of patients suffering from blocked arteries," said Suuronen. "The scaffold materials would direct the repair process, and restore blood flow and function to the heart."

The researchers tested this material in three groups of rats, with each group suffering from a lack of blood oxygen (ischemia) to their thigh muscles. The muscles in the first group of rats were treated with the smart scaffold. The second group of rats received a scaffold not engineered for cell attachment. The third group received a placebo. Two weeks after treatment, rats treated with the "smart" scaffold had mo
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. WCC Smart Search & Match Names Tarvinder Sembhi as VP Sales for the ID Market
2. WCC Smart Search and Match Names Rudie Lion - Product Marketing Manager
3. New smart materials for the brain
4. WCC Announces Version 6 of its ELISE Smart Search and Match Platform for Employment and Biometric Matching
5. WCC Smart Search and Match Names Rudie Lion - Product Marketing Manager
6. Brandeis and Smart Balance team up to advance heart-healthy research
7. e-Smart Technologies to Introduce Next Generation I AM Smart Card Technology at Cartes 2008 in Paris
8. Bee smart, bee healthy
9. JDRF to provide $1M in funding to SmartCells, Inc.
10. Full-Featured Video Analytics Platform Available in Smart Camera Format
11. Home Improvement Star Debbe Dunning is New smartTOUCH Spokesperson
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/29/2015)... 2015 Research and Markets( ... "Latin America Biomedical Sensors Market - Growth, Trends & ... The Latin America Biomedical Sensors market is estimated at ... over the period 2014-2020 The near future ... genetic formulation of each individual. These sensors can be ...
(Date:6/25/2015)... According to a new ... Area), Technology, Material (Optical Prism, Piezoelectric, Capacitive & ... Others) & Geography - Global Forecast to 2014 ... is expected to reach $14,500.07 Million by 2020, ... Browse 76 market Tables and 109 Figures spread ...
(Date:6/25/2015)... N.J. , June 25, 2015  TAKE Solutions ... a patent by the United States Patent and Trademark ... Standardization". This process leverages TAKE Solutions, Clinical Accelerators to ... over 50% (when compared to standardization without the accelerators), ... At the heart of ...
Breaking Biology News(10 mins):Latin America Biomedical Sensors Market Report 2015-2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4TAKE Solutions Awarded Patent By USPTO 2
... the Inderscience publication, the International Journal of Environment ... from various fields explain how living organisms can ... pollutants, particulates, and trace elements. Borut Smodi, ... provides an editorial explaining how biomonitoring can be ...
... on the theory that dinosaurs, closest living relatives are ... a 68-million-year-old Tyrannosaurus rex protein from the dinosaur,s femur ... chickens, ostriches, and to a lesser extent, alligators. ... rex femur discovered in 2003 by paleontologist John Horner ...
... Mont. -- Natural barriers like waterfalls play an important ... National Park, so maintaining those barriers should be a ... four-year study in the park. Park workers might ... the water from rising behind those barriers, said graduate ...
Cached Biology News:Biomonitoring 2Genetic sequencing of protein from T. rex bone confirms dinosaurs' link to birds 2Montana State researchers study spread of lake trout in Glacier National Park 2
(Date:7/27/2015)... , ... July 27, 2015 , ... ... of the Biophotonics industry.The report provides a basic overview of the industry including ... for the international markets including development trends, competitive landscape analysis, and key regions ...
(Date:7/27/2015)... MONTREAL , July 27, 2015   ... that produces sustainable biological accelerators for farmers, has ... Patent and Trademark Office for its patent application ... that accelerate plant growth and enhance yields on ... patent relates to Inocucor,s live IN-M1 microbial consortium ...
(Date:7/27/2015)... WORTH, Texas , July 27, 2015 ... Media Market by Type (Home-brew Media, Pre-formulated Media), by Application ... America , Europe , ... Forecast to 2019", The global biopreservation media market was valued ... to around $571.5 million by 2019, at a CAGR of ...
(Date:7/27/2015)... , July 27, 2015 IDEXX Laboratories, Inc. ... 8,000 clinics have submitted over 100,000 specimens to IDEXX ... just the first 10 days since the breakthrough kidney ... (CKD) is a leading cause of suffering and death ... specimens are consistent with generally accepted kidney disease prevalence ...
Breaking Biology Technology:2015 Biophotonics Market Global Research 22015 Biophotonics Market Global Research 3Inocucor Technologies Receives Groundbreaking U.S. Patent for Proprietary Biological Processes that Stimulate Plant Growth 2Inocucor Technologies Receives Groundbreaking U.S. Patent for Proprietary Biological Processes that Stimulate Plant Growth 3Global Biopreservation Media Market to be Worth $571.5 Million by 2019 2Global Biopreservation Media Market to be Worth $571.5 Million by 2019 3Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 2Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 3Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 4Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 5
... 14 GenVault Corporation today,announces that Mr. Mark ... of Business Development. Mr. Sutherland will be responsible ... licensing the company,s products and technologies as well ... Sutherland has more than 25 years experience in ...
... Oct. 14 Imaging,Diagnostic Systems, Inc., (OTC Bulletin ... imaging systems, announced today that its,distributor, Laszlo Meszaros ... Laser Mammography (CTLM(R)) system for Budapest, Hungary., ... system will be installed at the new MeDoc ...
... enable patient care services in Australia through ... retail pharmacies ... Convention --,Mirixa Corporation, the leader in pharmacy-based patient care services ... that they have signed a definitive technology licensing and business,consulting ...
Cached Biology Technology:Mark Sutherland Joins GenVault as Senior Vice President, Business Development 2Imaging Diagnostic Systems Sells Its CT Laser Mammography System to Budapest, Hungary 2Mirixa Announces Agreement With the Pharmacy Guild of Australia 2Mirixa Announces Agreement With the Pharmacy Guild of Australia 3