Navigation Links
Small mechanical forces have big impact on embryonic stem cells
Date:10/18/2009

ment of bioengineering. "The stiffer the stem cell, the less it spreads under stress."

The researchers obtained the same results when they applied cyclic forces to stiff human muscle cells. They did not experiment with human embryonic stem cells.

To study some of the long-term effects of localized mechanical forces on the behavior of mouse embryonic stem cells, the researchers utilized the expression of an enhanced green fluorescent gene. Cells expressing this gene glow fluorescent green when exposed to blue light.

As the mechanical force was applied in the researchers' experiments, the green fluorescence in cells with magnetic beads faded, indicating reduced gene expression. Control cells (without beads) a few microns away continued to glow.

"The softness of mouse embryonic stem cells makes them very sensitive to localized cyclic forces," Wang said. "If our findings can be extended to early animal embryos, they could provide a new way of locally differentiating a single cell of early lineage, while leaving nearby cells alone."


'/>"/>

Contact: James E. Kloeppel
kloeppel@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign
Source:Eurekalert

Page: 1 2

Related biology news :

1. Fate Therapeutics announces creation of small molecule platform for commercial-scale reprogramming
2. Conservation targets too small to stop extinction
3. Small molecule inhibits pathology associated with myotonic dystrophy type 1
4. Small rodents encourage the formation of scrubland in Spain
5. Harvard research team receives $10M NSF grant to develop small-scale mobile robotic devices
6. After dinosaurs, mammals rise but their genomes get smaller
7. Smaller than expected, but severe, dead zone in Gulf of Mexico
8. Smaller plants punch above their weight in the forest, say Queens biologists
9. New research shows dinosaurs may have been smaller than we thought
10. Small molecules mimic natural gene regulators
11. Small molecules might block mutant protein production in Huntingtons disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... Allan, PhD, a scientist at Western University and the ... spreads or metastasizes to the lung. , Breast cancer ... two cause of cancer-related deaths among women in North ... have a high success rate, but once the disease ... particular, the lung is one of the most common ...
(Date:4/24/2014)... (LMU) in Munich have identified the structural features ... between viral and endogenous RNAs in living cells. ... of cellular metabolism and hijack cellular resources for ... dependent on viral RNA molecules that are delivered ... and/or newly synthesized in the host cell, and ...
(Date:4/24/2014)... initiatives could be improved with new insights into the ... Scientists studying the Amazon Basin have revealed unprecedented detail ... the region by comparing satellite maps with hundreds of ... to assess more accurately the amount of carbon each ... carbon offset schemes, in which trees are given a ...
Breaking Biology News(10 mins):New study helps to explain why breast cancer often spreads to the lung 2Viral infections: Identifying the tell-tale patterns 2Viral infections: Identifying the tell-tale patterns 3Amazon rainforest survey could improve carbon offset schemes 2
... Sauvignon or a Pinot Noir grape variety, two new ... BMC Genomics, offer a host of new genetic information ... The grapevine,s gene expression analysis reveals two ... green and red grape stages. And researchers have reported ...
... PocketCop on BlackBerry Smartphones Keeps Officers ... Informed and In ... Board: BKYI), a leader in finger-based biometric,identification and wireless public safety, ... Office technology,deployment by KOCO Channel 5, the ABC affiliate in Oklahoma ...
... Researchers at the University of Pennsylvania School of Medicine ... enhance a vaccine used to study HIV in macaque ... HIV (SHIV) than an unmodified vaccine. This multi-year study ... effectively boosts the effects of a vaccine derived from ...
Cached Biology News:Ripening secrets of the vine revealed 2BIO-key(R) PocketCop(R) Project 'Leading the Nation' According to Televised Report 2Penn researchers find monkeys able to fend off AIDS-like symptoms with enhanced HIV vaccine 2
(Date:1/15/2014)... , January 15, 2014 A study has ... on the Formula 1 track could help to tackle the ... Technologies (MAT), Stowhealth (a GP surgery based in Stowmarket) and ... provider Simplyhealth. Telemetry technology, which is inspired by ...
(Date:1/15/2014)... 2014 DTS Language Services, Inc . ... Portal for Life Science organizations who need document translations. ... matter of their documents in advance with a selection of ... of translations, often a critical factor in clinical and scientific ...
(Date:1/15/2014)... TAIPEI , Jan. 15, 2014 TaiGen Biotechnology ... an exclusive agreement with R-Pharm, a leading Russian pharmaceutical ... in the Russian Federation , ... Commonwealth Independent States (CIS). Nemonoxacin is a novel antibiotic for ...
(Date:1/14/2014)...  3D Communications, a leading provider of strategic communications services to corporations ... in the United States and ... , JD, is returning to the firm,s Washington, D.C. ... after more than two years of service as Associate Commissioner for ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4DTS Improves Efficiency for Life Science Document Translations 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Former FDA Associate Commissioner Returns To 3D Communications 2
... Roy Eksteen, Tosoh Bioscience LLC, Montgomeryville, Pennsylvania and,Scott Lauder, Lexigen Pharmaceuticals, Lexington, Massachusetts ... Introduction: , During ... robustness. Factors such as elution profile, peak shape, and ... consistent by GMP/GLP protocols. During a recent method , ...
... Introduction , While ... HPLC as a reliable high efficiency technique, it has become apparent in , ... for reliable analysis , of highly polar compounds under ... was shown that by incorporating a polar group in the alkyl bonded phase , ...
... Contaminations of cell cultures show severe problems in the ... attention turns here particularly to the prevention , ... , that develop substances for therapeutic ... main focus., Endotoxins (Lipopolysaccharides, LPS) are biologically ...
Cached Biology Technology:Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column 2Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column 3Novel Bonding Chemistry Imparts Enhanced Polar Selectivity to TSK-GEL ODS-100V Reversed Phase Columns 2Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods 2Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods 3Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods 4Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods 5Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods 6Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods 7
Request Info...
NATIVE RAT OSTEOCALCIN...
... Chicken polyclonal to Opsin 1 ( Abpromise ... Antigen: Synthetic peptide: YEDSTHASIFTYT, corresponding to amino ... and synthetic peptide corresponding to amino acids 18/30 ... and used as immunogen. Entrez ...
EnzChek Ultra Xylanase Assay Kit *500 assays*...
Biology Products: