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Skywalker ensures optimal communication between neurons
Date:4/1/2011

uit flies unable to produce Skywalker. In these so-called sky flies, they noticed that broken-down proteins from the vesicles were more easily replaced, and that many more signaling substances were released than in the synapses of normal fruit flies. In other words, a lack of Skywalker increases the signal between two brain cells, resulting in overstressed flies.

But the discovery that inhibition of Skywalker leads to a stronger signal between brain cells offers possibilities for the fight against neurological diseases such as Parkinson's. In the early stages of these diseases, the signals between brain cells are too weak. Verstreken wants to study this further, but realizes that it will be an enormous challenge to find ways to maintain the subtle balance that ensures optimal communication.


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Contact: Joris Gansemans
joris.gansemans@vib.be
329-244-6611
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

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