Navigation Links
Skull shape risk factors could help in the welfare of toy dog breeds
Date:8/6/2014

New research has identified two significant risk factors associated with painful neurological diseases in the skull shape of the Cavalier King Charles Spaniel (CKCS). The findings could help in tackling these conditions in toy dog breeds and could be used in breeding guidelines.

The study conducted by undergraduate student, Thomas Mitchell, from the University of Bristol's School of Veterinary Sciences, and supervised by Dr Clare Rusbridge, is published online in the journal Canine Genetics and Epidemiology.

Syringomyelia (SM) is a painful condition in dogs and is more common in toy breeds. It involves the formation of fluid-filled cavities, known as syrinxes, in the spinal cord. This condition affects many popular toy breeds, including the CKCS and Chihuahua. In these toy breeds, SM is usually secondary to a specific malformation of the skull called Chiari-like Malformation, CM for short.

There has been debate as to whether head shape of these dogs is related to CM/SM, especially as some humans have similar characteristic facial and skull shapes, and what this may be. Identifying a head shape in dogs that is associated with these diseases would allow for selection away from these conditions and could be used to further breeding guidelines. Dogs were measured in several countries using a standardised "bony landmark" measuring system and photo analysis by trained researchers.

The researchers found two significant risk factors associated with CM/SM in the skull shape of the CKCS. These were the extent of the broadness of the top of skull relative to its length, also known as brachycephaly, and the distribution of doming of the skull. The study suggests that brachycephaly, with resulting doming towards the front of the head, is associated with CM/SM.

Thomas Mitchell said: "Dog breeders are very experienced at selecting for a certain conformation or appearance in dogs. Our findings may allow breeders to select away from the condition over fewer generations by choosing appropriate matings and offspring to continue breeding programmes. The identification of an appearance that might protect against developing the disease is a significant step forward in tackling this painful condition.

"The study also provides guidance to breed clubs, breeders and judges that have a responsibility to avoid obvious conditions or exaggerations which would be harmful in any way to the health, welfare or soundness of the breed. It will also provide vets with verified advice to provide to breeders outside the show ring and to occasional hobbyists."


'/>"/>
Contact: Joanne Fryer
joanne.fryer@bristol.ac.uk
44-011-733-17276
University of Bristol
Source:Eurekalert

Related biology news :

1. Skulls of red and giant pandas provide insight into coexistence
2. New study changes conceptions about the determinants of skull development and form
3. Ardi skull reveals links to human lineage
4. Fresh analysis of dinosaur skulls by penn researchers finds 3 species are 1
5. International team discovers likely basis of birth defect causing premature skull closure in infants
6. Old skull bone rediscovered
7. Key adjustment enables parasite shape-shifting
8. SLU scientists hit delete: Removing regions of shape-shifting protein explains how blood clots
9. New horned dinosaur reveals unique wing-shaped headgear
10. Did violence shape our faces?
11. Sneaky bacteria change key proteins shape to escape detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... India , April 28, 2016 ... Infosys (NYSE: INFY ), and Samsung SDS, a ... that will provide end customers with a more secure, ... services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) , ... services, but it also plays a fundamental part in enabling ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:4/13/2016)... physicians supporting Medicaid patients in Central Florida ... telehealth thanks to a new partnership with higi.   ... can routinely track key health measurements, such as blood ... they opt in, share them with IMPOWER clinicians through ... location at no cost. By leveraging this data, IMPOWER ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... ClinCapture, the only free validated ... will showcase its product’s latest features from June 26 to June 30, 2016 ... on Disrupting Clinical Trials in The Cloud during the conference. DIA (Drug ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... line of intelligent tools designed, tuned and optimized exclusively for Okuma CNC machining ... Chicago. The result of a collaboration among several companies with expertise in toolholding, ...
(Date:6/23/2016)... 23, 2016 ReportsnReports.com adds ... to its pharmaceuticals section with historic and forecast ... much more. Complete report on the ... profiling 15 companies and supported with 261 tables ... . The Global Cell Culture ...
(Date:6/22/2016)... , June 22, 2016 Research and Markets ... Markets" report to their offering. ... in 2014 from $29.3 billion in 2013. The market is expected ... 13.8% from 2015 to 2020, increasing from $50.6 billion in 2015 ... product forecasts during the forecast period (2015 to 2020) are discussed. ...
Breaking Biology Technology: