Navigation Links
Skin cancer identified for the first time in wild fish populations
Date:8/1/2012

Widespread skin cancer has been identified for the first time in wild marine fish populations, new research has shown.

A collaborative study between Newcastle University, UK, and the Australian Institute of Marine Science published today in the academic journal PLoS ONE - reveals the incidence of melanoma in the coral trout, a species found on the Great Barrier Reef and directly beneath the world's largest hole in the ozone layer.

This is the first time skin cancer has been diagnosed in wild fish populations and the team, led by Newcastle University's Dr Michael Sweet, say the appearance of the melanoma is almost identical to that found in humans.

"Further work needs to be carried out to establish the exact cause of the cancer but having eliminated other likely factors such as microbial pathogens and marine pollution, UV radiation appears to be the likely cause," explains Dr Sweet.

"Studying disease in wild fish populations is very time-consuming and costly so it's hard to say how long the disease has been around. However, what we do know is that it is now widespread in the coral trout population effecting three different species of this type of fish and we would not be surprised to find it in other species as well."

The study, which involved experts from Newcastle University, the Australian Institute of Marine Science and James Cook University, Australia, looked at Plectropomus leopardus, otherwise known as the common coral trout.

The coral trout is an iconic and highly valued species that occurs throughout the western Pacific and in Australia supports a high-value fishery on the Great Barrier Reef.

Diseased fish were caught in two locations in the southern Great Barrier Reef Marine Park Heron Island and One Tree Island but its occurrence throughout the rest of its range is currently unknown. Anecdotal evidence suggests minimal occurrence in other regions of the GBR and in other coral trout species, but further research is required to confirm this.

Of the 136 fish sampled, 20 (15%) showed dark lesions on the skin the lesions covered as little as 5% of the skin ranging to full coverage and an almost entirely black appearance.

Dr Sweet said the numbers were significant.

"The individuals we looked at had extensive but only surface melanomas," he explained.

"This means the cancer had not spread any deeper than the skin so apart from the surface lesions the fish were basically healthy.

"Once the cancer spreads further you would expect the fish to become quite sick, becoming less active and possibly feeding less, hence less likely to be caught. This suggests the actual percentage affected by the cancer is likely to be higher than observed in this study."

UV-induced melanoma in fish has until now only been seen under laboratory conditions and has been used as a model to study the progress of human skin cancer due to the similarities in the disease.

In the lab, hybridised fish were found to be more susceptible to UV radiation due to exposure of the so-called 'Xmrk' gene. In the case of coral trout cross-breeding or hybridisation may also be occurring and play a role in the coral trout's susceptibility to the disease.

Dr Michelle Heupel from the Australian Institute of Marine Science stated: "This is a crucial finding in an iconic and high value reef species.

"Given climate change scenarios and continuing alteration of coral reef environments understanding the cause of this disease is important to continued conservation and management of reefs and their inhabitants."

The next step in the study is to look at a much larger sample and determine the extent of disease presence and causation within the populations.


'/>"/>
Contact: Louella Houldcroft
louella.houldcroft@ncl.ac.uk
44-019-122-25108
Newcastle University
Source:Eurekalert

Related biology news :

1. Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
2. Embryonic development protein active in cancer growth
3. BRG1 mutations confer resistance to hormones in lung cancer
4. Genetic variation in East Asians found to explain resistance to cancer drugs
5. Beyond the microscope: Identifying specific cancers using molecular analysis
6. Marshall University study may lead to new treatments for prostate cancer
7. Salk scientists open new window into how cancers override cellular growth controls
8. Penn research points to new way of preserving fertility for boys undergoing cancer treatment
9. Genetic abnormality offers diagnostic hope for childrens cancer
10. Protein jailbreak helps breast cancer cells live
11. Breast cancer risk gene discovery fast tracked by new technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2016)... -- As part of its longstanding mission to improve genetic literacy ... released its latest children,s book, titled The One ... topics of inheritance and variation of traits that are part ... school classrooms in the US. The book ... Killoran , whose previous book with 23andMe, You ...
(Date:12/16/2016)... 2016   IdentyTechSolutions America LLC , a ... solutions and a cutting-edge manufacturer of software and ... offering seamless, integrated solutions that comprise IDT biometric ... solutions provide IdentyTech,s customers with combined physical identification ... crime and theft. "We are proud ...
(Date:12/15/2016)... ... has announced the addition of the "Global Military Biometrics Market 2016-2020" ... global military biometrics market to grow at a CAGR of 7.5% during ... on an in-depth market analysis with inputs from industry experts. The report ... The report also includes a discussion of the key vendors operating in ...
Breaking Biology News(10 mins):
(Date:1/16/2017)... ... January 16, 2017 , ... Appellate Court of ... on the appeal filed by India-based Dishman Pharmaceutical & Chemical Ltd. company (DPCL) ... and one of its Dishman Group’s 100% wholly owned New Jersey-based subsidiary Dishman ...
(Date:1/16/2017)... ... 16, 2017 , ... Attagene , a Research Triangle ... Small Business Administration. The Tibbetts Award honors the Small Business Innovation Research ... are considered the best of the best from the thousands of firms that ...
(Date:1/14/2017)... , ... January 14, 2017 , ... ... new service providing complete end-to-end genome assemblies to researchers around the globe. ... a major obstacle in answering a wide range of scientific questions. The ...
(Date:1/13/2017)... 2017 Research and Markets has announced the ... Global Forecast to 2021" report to their offering. ... The biosimilars market is ... Billion in 2016, at a CAGR of 26.3%. ... manufacturing type, and application. Factors such as rising incidence of various ...
Breaking Biology Technology: