Navigation Links
Single-cell parasites co-opt 'ready-made' genes from host: UBC research
Date:7/18/2012

Two species of single-cell parasites have co-opted "ready-made" genes from their hosts that in turn help them exploit their hosts, according to a new study by University of British Columbia and University of Ottawa researchers.

Part of a group of parasitic microbes called microsporidia, Encephalitozoon hellem and Encephalitozoon romaleae are related to fungi and are commonly found in the intestines of vertebrates. In humans, they are associated with people with immune deficiencies.

The research team identified six genes in these parasites that were not found in any other microsporidian. Rather than the slow process of inheriting individual genes, E. hellem and E. romaleae have acquired a suite of genes that produce folate, a form of folic acid that helps cell division and growth.

"With their tiny, reduced genomes, microsporidia are models for gene loss," says lead author Patrick Keeling, a professor in UBC's Dept. of Botany.

"These parasites have undergone massive genome reductions and are literally infection machines they only kept genes that are essential for survival."

"But here we found two species have actually acquired new genes that work together to make an essential nutrient that the parasites would otherwise have to steal from their host opening up new tissues or even new hosts as targets for infection," says Keeling, director of the Centre for Microbial Diversity and Evolution and a member of Beaty Biodiversity Research Centre at UBC.

The process of horizontal gene transfer the ability to acquire ready-made genes with specific functions from foreign genomes is an important but often overlooked mechanism of evolution, according to Keeling. "It helps explain the relatively rapid evolution of these tiny organisms and their ability to infect and live off of a wide variety of hosts."


'/>"/>

Contact: Brian Lin
brian.lin@ubc.ca
60-048-222-234
University of British Columbia
Source:Eurekalert

Page: 1

Related biology news :

1. Nanobubbles plus chemotherapy equals single-cell cancer targeting
2. Elsevier launches International Journal for Parasitology: Parasites and Wildlife
3. T cells hunt parasites like animal predators seek prey, a Penn Vet-Penn Physics study reveals
4. Scientists find Achilles heel in life-threatening malaria parasites
5. Weakness can be an advantage in surviving deadly parasites, a new study shows
6. Exome sequencing of health condition extremes can reveal susceptibility genes
7. Genes may play role in educational achievement, study finds
8. World experts meet in Edinburgh to consider how life experiences impact on our genes
9. Parasitic plants steal genes from their hosts
10. Manipulating chromatin loops to regulate genes may offer future treatments for blood diseases
11. Its in the genes: Research pinpoints how plants know when to flower
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... N.Y., Aug. 4, 2015  AMRI (NASDAQ: AMRI ) today ... 30, 2015. Highlights: , Second quarter contract ... from 2014 , Adjusted contract margins of ... of $0.22, including a $0.05 decrease in EPS from royalties in ... $16 million "We are very pleased to present ...
(Date:7/31/2015)... SHENZHEN, China , 31 de julio de 2015 ... sobre Genómica (ICG-10,  www.icg-10.org ) del 22 al 25 ... . La conferencia celebra su décimo ... se ha convertido en una de las reuniones anuales ... ,ómicas, y es una de las conferencias científicas más ...
(Date:7/31/2015)... julio de 2015 La 10 th International ... medio de BGI del 22 al 25 de octubre de 2015 ... Este año, la conferencia celebra su décimo aniversario. Desde su ... una de las reuniones anuales más influyentes del mundo en ... más dinámicas, entusiastas y mejores a nivel científico. ...
Breaking Biology News(10 mins):AMRI Announces Second Quarter 2015 Results 2AMRI Announces Second Quarter 2015 Results 3AMRI Announces Second Quarter 2015 Results 4AMRI Announces Second Quarter 2015 Results 5AMRI Announces Second Quarter 2015 Results 6AMRI Announces Second Quarter 2015 Results 7AMRI Announces Second Quarter 2015 Results 8AMRI Announces Second Quarter 2015 Results 9AMRI Announces Second Quarter 2015 Results 10AMRI Announces Second Quarter 2015 Results 11AMRI Announces Second Quarter 2015 Results 12AMRI Announces Second Quarter 2015 Results 13AMRI Announces Second Quarter 2015 Results 14AMRI Announces Second Quarter 2015 Results 15AMRI Announces Second Quarter 2015 Results 16AMRI Announces Second Quarter 2015 Results 17AMRI Announces Second Quarter 2015 Results 18AMRI Announces Second Quarter 2015 Results 19AMRI Announces Second Quarter 2015 Results 20AMRI Announces Second Quarter 2015 Results 21AMRI Announces Second Quarter 2015 Results 22AMRI Announces Second Quarter 2015 Results 23AMRI Announces Second Quarter 2015 Results 24La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3
... problem, there is a greater risk that you will consume ... Sahlgrenska Academy, at the University of Gothenburg, Sweden. ,It ... likely to have a drink problem in the future, and ... on this link. Carried out by researcher Anna Sderpalm Gordh, ...
... of Energy,s (DOE) Brookhaven National Laboratory and collaborators at the ... where to insert a double bond when desaturating plant fatty ... amino acid far from the enzyme,s active site solves ... control. The work, published in the Proceedings of the ...
... SuviCa Inc. of Boulder and the University of Colorado ... drug screening technology to identify novel therapies for cancer. ... CU-Boulder Associate Professor Tin Tin Su of the molecular, ... Drosophila fruit fly model to screen for compounds effective ...
Cached Biology News:Scientists solve long-standing plant biochemistry mystery 2Scientists solve long-standing plant biochemistry mystery 3Scientists solve long-standing plant biochemistry mystery 4SuviCa Inc. of Boulder to commercialize CU-Boulder cancer screening technology 2
(Date:8/31/2015)... Milpitas, Calif. (PRWEB) , ... August 31, 2015 ... ... earlier this year to bring together supply chain risk management and resiliency practitioners ... collaborate, develop and share best practices, and be recognized for their innovations and ...
(Date:8/31/2015)... , Aug. 31, 2015 Research and ... the "Argentina Biomedical Sensors Market - Growth, Trends ... The Argentina Biomedical Sensors market is estimated ... 1.17% over the period 2014-2020 The near ... the genetic formulation of each individual. These sensors can ...
(Date:8/31/2015)... -- For people with Down syndrome, news from Elixirgen, ... located in the Science + Technology Park at Johns ... yet for people with Down syndrome and other chromosome disorders ... and Edwards syndrome aneuploidies in human cell cultures, " ... plans to develop this technology into a treatment for ...
(Date:8/31/2015)... SHANGHAI , Aug. 31, 2015 /PRNewswire/ ... next-generation antibiotics, today announced positive top-line results from ... lead drug candidate MRX-I. MRX-I is an oral ... as MRSA and VRE, while offering physicians and ... than currently available oxazolidinone agents. ...
Breaking Biology Technology:Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 3Argentina Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts 2014-2020 2New Down syndrome therapy discovered 2MicuRX Reports Positive Top-Line Results In Phase 2 Clinical Trial For Novel Antibiotic MRX-I In Complicated Skin And Soft Tissue Infections 2
... - Engineers at Rensselaer Polytechnic Institute have developed tools to ... of stem cell research how to quickly test stem ... create a large supply of healthy, viable stem cells to ... have created methods to study millions of stems cells on ...
... to discover life on Mars were successfully launched into ... experiment to assess their survivability in the space radiation ... approach is based on technology similar to that used ... in the Life Marker Chip (LMC) experiment, which has ...
... engineers often deal with the same problems, but they ... other can be difficult, if not impossible., A new ... by the National Science Foundation (NSF), will help bridge ... to solve common problems a range of scientists face., ...
Cached Biology Technology:Putting stem cell research on the fast track 2Putting stem cell research on the fast track 3Putting stem cell research on the fast track 4Life on Mars 'pregnancy test' successfully launched 2CCMR gets $2.9M for training grad students in nanoscale science 2
... an excellent choice for supporting hydrocarbon processing. In ... this one-channel workhorse can double sample throughput by ... You get all the capability and reliability you ... that has the same proven performance of Agilents ...
... animal infusion kits reduce the time and ... while providing sterile equipment to reduce the ... you need for one animal, including swivel, ... will be cut to the exact lengths ...
... new chapter to a 40-year ... 7890A GC gives you everything ... lab to the next level ... including advanced separation capabilities, powerful ...
... Gene silencing experiments often call for ... NeoFX Transfection Agent refines siRNA transfection ... NeoFXs lipid-based formulation can be used ... they are subcultured without increased ...
Biology Products: