Navigation Links
Single cell injections
Date:8/9/2010

Duke University physicists have developed a way to produce sharp fluid jets with enough precision that they can inject material into a single, living cell. The technique promises a way to deliver drugs to cells one at a time, which is likely to be very valuable for research involving stem cells and other cellular-level studies. The research appears in the current issue of the APS journal Physical Review Letters.

The physicists produced the jets by focusing lasers into a fluid surrounding a target cell. The lasers heated molecules of a blue dye dissolved in the fluid, which in turn created tiny bubbles to rapidly grow and collapse. When these sorts of bubbles are produced individually, they create shock waves that spread throughout the liquid. But producing two adjacent bubbles in rapid succession results in small, powerful jets capable of poking tiny holes, measuring only 0.2 millionths of a meter across, in cell membranes.

The researchers confirmed that the jets allowed the introduction of fluids into the cell by checking for signs of the blue dye inside the pierced cells. The dye is toxic, and it killed the pierced cells, but the holes the jets produced were small enough that it's likely that the jets will offer a way to inject live cells with nontoxic substances without significantly damaging them.

Claus-Deiter Ohl of Nanyang Technological University in Singapore provides further information about the fluid jets and related research in a Viewpoint article in the current edition of APS Physics (physics.aps.org).


'/>"/>

Contact: James Riordon
riordon@aps.org
301-209-3238
American Physical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Salk researchers successfully reprogram keratinocytes attached to a single hair
2. Reprogrammable cell type depends on a single gene to keep its identity
3. Einstein researchers develop technique to count messages made by single genes
4. Single adult stem cell can self renew, repair tissue damage in live mammal
5. Single virus used to convert adult cells to embryonic stem cell-like cells
6. Large DNA stretches, not single genes, shut off as cells mature
7. Single gene lets bacteria jump from host to host
8. Scientists discover why teeth form in a single row
9. Texas-sized tract of single-celled clones
10. Distinguishing single cells with nothing but light
11. Olympus advances technology for laparo-endoscopic single-site surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Single cell injections
(Date:3/22/2017)... , March 21, 2017   Neurotechnology , ... recognition technologies, today announced the release of the ... which provides improved facial recognition using up to ... a single computer. The new version uses deep ... accuracy, and it utilizes a Graphing Processing Unit ...
(Date:3/16/2017)... HANOVER, Germany , March 16, 2017 CeBIT 2017 - Against ... Continue Reading ... Used combined in one project, multi-biometric solutions ... ... Identification Systems) ...
(Date:3/7/2017)... 7, 2017   HireVue , the leading provider ... identify the best talent, faster, today announced the additions ... (CSO) and Diana Kucer as Chief Marketing ... executive team poised to drive continued growth in the ... year of record bookings in 2017. "Companies ...
Breaking Biology News(10 mins):
(Date:3/24/2017)... MOSCOW and ROCKVILLE, Md. ... portfolio company of Maxwell Biotech Venture Fund (MBVF), today ... of SQ109 added to the standard drug therapy regimen ... a new small molecule drug discovered by scientists at ... US National Institutes of Health. A ...
(Date:3/24/2017)... LEXINGTON, Mass. , March 24, 2017 ... pipeline of immune checkpoint antibodies and cancer vaccines, today ... The 7 th  Annual William Blair and Maidstone ... Event Space Alexandria Center in New York, ... March 29 at 9:40 am: ...
(Date:3/23/2017)... , March 23, 2017  SeraCare Life ... global in vitro diagnostics manufacturers and clinical ... industry,s first multiplexed Inherited Cancer reference ... by next-generation sequencing (NGS). The Seraseqâ„¢ Inherited ... with input from industry experts to validate ...
(Date:3/23/2017)... March 23, 2017 NetworkNewsWire Editorial Coverage  ... Cancer ... significant strain on health care systems, in terms of costs ... so too does the development of innovative and efficient therapies ... Among the many types of cancer treatments, a growing number ...
Breaking Biology Technology: