Navigation Links
Single cell injections
Date:8/9/2010

Duke University physicists have developed a way to produce sharp fluid jets with enough precision that they can inject material into a single, living cell. The technique promises a way to deliver drugs to cells one at a time, which is likely to be very valuable for research involving stem cells and other cellular-level studies. The research appears in the current issue of the APS journal Physical Review Letters.

The physicists produced the jets by focusing lasers into a fluid surrounding a target cell. The lasers heated molecules of a blue dye dissolved in the fluid, which in turn created tiny bubbles to rapidly grow and collapse. When these sorts of bubbles are produced individually, they create shock waves that spread throughout the liquid. But producing two adjacent bubbles in rapid succession results in small, powerful jets capable of poking tiny holes, measuring only 0.2 millionths of a meter across, in cell membranes.

The researchers confirmed that the jets allowed the introduction of fluids into the cell by checking for signs of the blue dye inside the pierced cells. The dye is toxic, and it killed the pierced cells, but the holes the jets produced were small enough that it's likely that the jets will offer a way to inject live cells with nontoxic substances without significantly damaging them.

Claus-Deiter Ohl of Nanyang Technological University in Singapore provides further information about the fluid jets and related research in a Viewpoint article in the current edition of APS Physics (physics.aps.org).


'/>"/>

Contact: James Riordon
riordon@aps.org
301-209-3238
American Physical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Salk researchers successfully reprogram keratinocytes attached to a single hair
2. Reprogrammable cell type depends on a single gene to keep its identity
3. Einstein researchers develop technique to count messages made by single genes
4. Single adult stem cell can self renew, repair tissue damage in live mammal
5. Single virus used to convert adult cells to embryonic stem cell-like cells
6. Large DNA stretches, not single genes, shut off as cells mature
7. Single gene lets bacteria jump from host to host
8. Scientists discover why teeth form in a single row
9. Texas-sized tract of single-celled clones
10. Distinguishing single cells with nothing but light
11. Olympus advances technology for laparo-endoscopic single-site surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Single cell injections
(Date:6/2/2016)... 2016 The Department of Transport Management ... 44 million US Dollar project, for the , ... Personalization, Enrolment, and IT Infrastructure , to ... and implementation of Identity Management Solutions. Numerous renowned international vendors ... Decatur was selected for the most compliant and ...
(Date:5/24/2016)... patient care by providing unparalleled technology to leaders of the medical imaging industry.  As ... added to the range of products distributed by Ampronix. Photo - ... ... ... ...
(Date:5/9/2016)... 9, 2016 Elevay is currently ... expanding freedom for high net worth professionals seeking travel ... globally connected world, there is still no substitute for ... duplicate sealing your deal with a firm handshake. This ... taking advantage of citizenship via investment programs like those ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... MA (PRWEB) , ... June 23, 2016 , ... ... Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute ... platform of microbial tests introduced last year,” stated Bob Salter, Vice President of ...
(Date:6/23/2016)... FRANCISCO , June 23, 2016   EpiBiome ... has secured $1 million in debt financing from Silicon ... ramp up automation and to advance its drug development ... its new facility. "SVB has been an ... beyond the services a traditional bank would provide," said ...
(Date:6/23/2016)... , ... June 23, 2016 , ... In a new ... in Denmark detail how a patient who developed lymphedema after being treated for breast ... results could change the paradigm for dealing with this debilitating, frequent side effect of ...
(Date:6/23/2016)... -- Andrew D Zelenetz , ... Published recently in Oncology & ... Andrew D Zelenetz , discusses the fact ... placing an increasing burden on healthcare systems worldwide, ... the patents on many biologics expiring, interest in ...
Breaking Biology Technology: