Navigation Links
Singapore scientists join international study of 10,000 vertebrates' genomes

The Singapore laboratory that deciphered the DNA codes, or genomes, of the famed fugu (or pufferfish) and elephant shark, has joined The Genome 10K Project, an international effort to build an invaluable repository of DNA sequences on 10,000 species of animals for conducting comparative studies on a scale that currently can not be achieved.

Participating in The Genome 10K project, described in a paper published in the Nov. 5, 2009 issue of the Journal of Heredity, are 70 leading scientists at major zoos, museums, research centres and universities in North and South America, Europe, Australia as well as Asia. They will create a collection of tissue and DNA samples and then sequence and analyze the animals' genomes to reveal the complete genetic heritage of the 10,000 species.

The results will enable scientists worldwide to understand the genetic basis of adaptive changes that occur in vertebrates and predict how animals respond to climate change, pollution, emerging diseases and competition. In addition to aiding conservation efforts, this data will enable researchers to compare animal and human genomes, and reconstruct the evolutionary history of the human and other vertebrate genomes.

"The most challenging intellectual problem in biology for this century will be the reconstruction of our biological past so we can understand how complex organisms such as ourselves evolved," said Nobel Laureate Sydney Brenner, M.D., who co-heads Singapore's Institute of Molecular and Cell Biology (IMCB) comparative genomics laboratory, which will participate in The Genome 10 K Project.

"Genomes contain information from the past they are molecular fossils and having sequences from vertebrates will be an essential source of rich information," added Dr. Brenner, who also is Scientific Advisor to the Chairman of Singapore's A*STAR (Agency for Science, Technology and Research), which oversees 14 biomedical sciences, and physical sciences and engineering research institutes, and seven consortia and centres at Biopolis and Fusionopolis, as well as their immediate vicinity.

One of the initiators of the Genome 10K project, David Haussler, Ph.D., Professor of Biomolecular Engineering at University of California, Santa Cruz, said, "For the first time, we have a chance to really see evolution in action, caught in the act of changing whole genomes. This is possible because the technology to sequence DNA is thousands of times more powerful now than it was just a decade ago, and is poised to get even more powerful very soon."

Byrappa Venkatesh, Ph.D., who heads IMCB's comparative genomics lab and is one of the chairpersons of the Genome 10K committee, said, "This project will not only generate sequences of all important vertebrate genomes that we were contemplating to sequence, but also will give us access to the latest sequencing technologies and sequence analysis tools for genomic studies in Singapore."

IMCB Executive Director Neal Copeland, Ph.D., added, "We are delighted and honored that IMCB is participating in this momentous project, which is a fine example of the international nature of science. Following the successful revelation of the fugu genome in 2002, IMCB is looking forward to making even more important contributions to the international field of genomics through the Genome 10K project and remains committed to using the tools of modern science to make important, basic discoveries that will advance the understanding of the human genome and diseases."


Contact: Yunshi Wang
Agency for Science, Technology and Research (A*STAR), Singapore

Related biology news :

1. MINDEF, NTU join hands to boost Singapores defense R&D capabilities
2. New Singapore-France research alliance to develop state-of-the-art nanotechnologies
3. Facile synthesis of nanoparticles with multiple functions advanced in Singapore
4. Singapore nanotechnology combats fatal brain infections
5. Singapore scientists elected into National Academy of Sciences
6. Alzheimers, asthma, cancer, malaria and TB focus of new Singapore grants
7. Singapore scientists synthesize gold to shed light on cells inner workings
8. Singapore researchers first to transform carbon dioxide into methanol
9. First tri-continuous mesoporous Silica complex structure developed in Singapore
10. Regulatory molecule for tumor formation or suppression identified by Singapore, US researchers
11. The Earth Observatory of Singapore devoted to the study of earth sciences officially opens
Post Your Comments:
(Date:5/12/2016)... May 12, 2016 , a ... the overview results from the Q1 wave of its ... wave was consumers, receptivity to a program where they ... a health insurance company. "We were surprised ... says Michael LaColla , CEO of Troubadour Research, ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 /PRNewswire/ ... product subsidiary of Infosys (NYSE: INFY ), and ... global partnership that will provide end customers with ... banking and payment services.      (Logo: ... area for financial services, but it also plays a fundamental ...
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
(Date:6/23/2016)... ... ... In a new case report published today in STEM CELLS Translational Medicine, doctors ... being treated for breast cancer benefitted from an injection of stem cells derived from ... frequent side effect of cancer treatment. , Lymphedema refers to the swelling ...
(Date:6/23/2016)... , June 23, 2016 On Wednesday, ... at 4,833.32, down 0.22%; the Dow Jones Industrial Average edged ... closed at 2,085.45, down 0.17%. has initiated coverage on ... ), Nektar Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals ... (NASDAQ: BIND ). Learn more about these stocks ...
Breaking Biology Technology: