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Singapore scientists first to perform genome-wide study of human stem cells
Date:10/18/2010

nding of hESCs and this will help in the development of technologies to further the utilities of these cells such as their potential to be used for clinical and therapeutic applications," said Dr Ng. "Dr Bard's scientific expertise was invaluable in helping us crack another piece of the stem cell puzzle. I definitely look forward to collaborating with him on more projects that aim to peel away the mysteries surrounding stem cells" he added.

Dr Alan Colman, Executive Director of the Singapore Stem Cell Consortium, said, "Huck Hui Ng and his colleagues continue to keep Singapore at the top table of countries plundering the secrets of human embryonic stem cell regulation. This time they have deployed the first genome-wide functional screen to identify factors that maintain 'stemness' in these cells and yet again reveal major differences between mouse and human embryonic stem cells in the control of this important property."

Senior Scientist at the Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Dr Janet Rossant added, "The unprecedented scale of this screen has added considerable new information to our understanding of pluripotency and will help efforts to improve reprogramming of adult cells."

Professor Lee Eng Hin, Executive Director of the Biomedical Research Council, A*STAR, applauded the discovery and said, "This is an examplar of a great cross institutional collaboration. The combined strength of stem cell and genomics experts has led to a great piece of world-class work. I hope to see more of such valuable partnerships in the future."


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Contact: Joshua Tan
joshua_tan@a-star.edu.sg
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

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