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Singapore scientists exploit knowledge of p53 for increasing specificity of cancer treatments
Date:5/24/2010

tlin-like drugs will allow such exciting concepts to be tested in the clinic. We hope that this work encourages further breakthroughs in p53 research and brings more efficient and cost-effective treatments for the millions of cancer patients worldwide."

Dr Cheok said, "One the most difficult problems in treating cancer is ensuring that normal, healthy cells are not killed over the course of treatment. Many of the currently available methods of treatment, such as chemotherapy and radiation therapy, damage normal cells in the process of killing cancer cells. We are using our knowledge of p53 to overcome this difficulty."

Dr Cheok was among the first few Singaporeans to embark on a PhD scholarship from A*STAR in 2001 . After receiving her PhD from the University of Oxford, she began her post-doctoral training under the tutelage of Prof Lane in 2006. She is also an Assistant Professor and a Senior Research Fellow at the Department of Biochemistry at the Yong Loo Lin School of Medicine, NUS.

Prof Lane added, "We are proud of Chit Fang for having made this significant finding so early in her scientific career. It gives me great pleasure to have her as part of my team working on deepening our understanding of how to use basic science findings to develop new therapies."


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Contact: Joshua Tan
joshua_tan@a-star.edu.sg
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

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