Navigation Links
Simplicity is crucial to design optimization at nanoscale
Date:2/4/2009

MIT researchers who study the structure of protein-based materials with the aim of learning the key to their lightweight and robust strength have discovered that the particular arrangement of proteins that produces the sturdiest product is not the arrangement with the most built-in redundancy or the most complicated pattern. Instead, the optimal arrangement of proteins in the rope-like structures they studied is a repeated pattern of two stacks of four bundled alpha-helical proteins.

This composition of two repeated hierarchies (stacks and bundles) provides great strengththe ability to withstand mechanical pressure without giving wayand great robustnessthe ability to perform mechanically, even if flawed. Because the alpha-helical protein serves as the building block of many common materials, understanding the properties of those materials has been the subject of intense scientific inquiry since the protein's discovery in the 1940s.

In a paper published in the Jan. 27 online issue of Nanotechnology, Markus Buehler and Theodor Ackbarow describe a model of the protein's performance, based on molecular dynamics simulations. With their model they tested the strength and robustness of four different combinations of eight alpha-helical proteins: a single stack of eight proteins, two stacks of four bundled proteins, four stacks of two bundled proteins, and double stacks of two bundled proteins. Their molecular models replicate realistic molecular behavior, including hydrogen bond formation in the coiled spring-like alpha-helical proteins.

"The traditional way of designing materials is to consider properties at the macro level, but a more efficient way of materials' design is to play with the structural makeup at the nanoscale," said Buehler, the Esther and Harold E. Assistant Professor in the Department of Civil and Environmental Engineering. "This provides a new paradigm in engineering that enables us to design a new class of m
'/>"/>

Contact: Denise Brehm
brehm@mit.edu
617-253-8069
Massachusetts Institute of Technology, Department of Civil and Environmental Engineering
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Speed plays crucial role in breaking proteins H-bonds
2. Brown scientists say biodiversity is crucial to ecosystem productivity
3. Hidden infections crucial to understanding, controlling disease outbreaks
4. Mayo researchers identify dangerous two-faced protein crucial to breast cancer spread and growth
5. In lung cancer, silencing one crucial gene disrupts normal functioning of genome
6. IGERT fellows to design biodevices using flexible electronics
7. Researchers successfully simulate photosynthesis and design a better leaf
8. Synaptics SecurePad(TM) Selected as CES Innovations 2008 Design and Engineering Award Honoree
9. Singulex Teams With Wyeth Pharmaceuticals to Translate Pre-Clinical Biomarker Research Into Clinical Study Design
10. HIV isolate from Kenya provides clues for vaccine design
11. Book is the first high-resolution digital mouse brain atlas designed for Web applications
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Simplicity is crucial to design optimization at nanoscale
(Date:2/11/2015)... 2015 According to ... Market by Product (Cards and Readers, Biometrics, Controllers, Management ... Industrial, Healthcare, Education) and By Geography - Global Forecast and Analysis ... Access Control Market is expected to reach ... CAGR of 10.6% between 2014 and 2020. ...
(Date:2/5/2015)... North Carolina , 5. Februar 2015 ... Jahr als spezialisiertes Logistikunternehmen und hat eine ... einzige klinische Logistikfirma (Clinical Logistics Organization – ... der neuen Kampagne lautet First , ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
(Date:2/5/2015)... Conn. , Jan. 26, 2015 NXT-ID, Inc. ... the "Company"), a biometric authentication company focused on the ... new corporate website ( http://www.nxt-id.com/ ) as part of ... smart wallet. The Company launched its new consumer website ... Gino Pereira , CEO of NXT-ID said, "Our new ...
Breaking Biology News(10 mins):Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 3
... A University of Granada researcher has been awarded the ... Meeting, an international conference of computed microtomography recently celebrated in ... Zoology has been awarded for his biofilm titled Micro-CT anatomical ... the genus Dryops . This film shows from the ...
... of California, Riverside have a "proof of concept" that ... behavior and survival of honey bees. Selenium ... normal development of insects and humans but ... replaces sulfur in amino acids. In soils, particularly ...
... named as the lead university in the United Kingdom ... and engineering., It is the only UK University to ... SWAN Charter awards, which recognise the commitment of institutions, ... gender inequalities and improving career progression for female academics., ...
Cached Biology News:Spanish researcher releases a video showing a beetle from the inside 2Selenium impacts honey bee behavior and survival 2Selenium impacts honey bee behavior and survival 3Queen's is UK leader for female scientists and engineers 2
(Date:2/26/2015)... , Feb. 26, 2015   Regulus Therapeutics ... company leading the discovery and development of innovative medicines ... , Ph.D., President and Chief Executive Officer of Regulus, ... Company 35 th Annual Healthcare Conference on Wednesday, ... is being held at the Boston Marriott Copley Place.  ...
(Date:2/26/2015)... 26, 2015  NuGene International, Inc. ("NuGene") (OTCQB: ... skin and hair rejuvenation, has announced that it ... record for investor relations and strategic communications. ... sales and diversification strategies – and we need ... shareholders," stated Ali Kharazmi CEO of NuGene when ...
(Date:2/26/2015)... 2015 Innovation is more urgent ... unexpected parts of the world and transforming global ... to manufacturing to health care, disruption is constantly ... and socio-political trends shake the foundations of established ... for CEOs to survive the next wave of ...
(Date:2/26/2015)... 2015 Ceres, Inc . today announced ... PartnerNetwork. In attaining Gold Level membership, Ceres has been ... knowledge in delivering Ceres, Persephone genome visualization software and ... Originally developed for in-house use by Ceres, the ... out of massive amounts of genetic data, from a ...
Breaking Biology Technology:Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 2Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 3NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 2NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 3One Million Acts of Innovation Canada Creates Partnership with The Economist Events’ Innovation Forum 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4
... Generation Pro-Healing Technology Developments UnveiledSEOUL, South Korea, April ... at a symposium during Angioplasty Summit TCT Asia ... Grande Walkerhill Hotel in Seoul, South Korea. ... Medical Center (AMC), Amsterdam, The Netherlands, final adjudicated ...
... Microtest Laboratories ( www.microtestlabs.com ) ... its position as a proven, one-stop provider of contamination ... for manufacturers of medical devices or pharmaceuticals.Microtest helps manufacturers ... compliance as well as to achieve greater productivity. ...
... Young Companies will Present at the Largest Marketplace for ... NSTI and CTSI today announced that more than 100 ... commercialization partners will be showcased in the 4th Annual ... George R. Brown Convention Center in Houston, Texas. ...
Cached Biology Technology:OrbusNeich's Genous(TM) Bio-engineered R stent(TM) Demonstrates Impressive Results in Higher Risk Patients 2OrbusNeich's Genous(TM) Bio-engineered R stent(TM) Demonstrates Impressive Results in Higher Risk Patients 3Microtest Labs Expands Clean Room, Contamination Testing Services 2Microtest Labs Expands Clean Room, Contamination Testing Services 3Microtest Labs Expands Clean Room, Contamination Testing Services 4TechConnect Summit Brings the Global Technology Community to Houston, May 4-6, 2009 2TechConnect Summit Brings the Global Technology Community to Houston, May 4-6, 2009 3TechConnect Summit Brings the Global Technology Community to Houston, May 4-6, 2009 4
... is a direct antibiotic-based ... identification. Recombinant selection depends ... eliminating the need for ... quick and inexpensive process ...
... has been designed and created in order ... friendly genotyping analysis tool. We incorporated the ... into the software. Their main requirements were ... low acquisition cost. GeneMarker can perform ...
... phase extraction through columns is a well-known ... applications. Typical applications are in DNA/RNA extraction ... or compound purification in chemical or analytical ... on the Genesis series instruments for smaller ...
... 3D structure visualization, phylogenetic tree building, sequence ... single application. Retrieve ... and filter them in real-time Organize ... searching, filtering and sorting Provides up-to-date ...
Biology Products: