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Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines
Date:2/29/2008

pulation has CKD, while awareness of kidney disease among the general public remains very low," states Dr. Heejung Bang, assistant professor in the Division of Biostatistics and Epidemiology in the Department of Public Health at Weill Cornell Medical College and lead author of the study. "This information underscores the need to be more vigilant in detecting those at risk of CKD in the general population," she says.

SCORED remains the first and only scoring instrument rigorously developed by statistical modeling for general population screening, as reported one year ago -- in the Feb. 26, 2007, Archives of Internal Medicine. It employs a user-friendly questionnaire and a simple scoring system based on seven risk factors for CKD -- age, sex, hypertension, diabetes, cardiovascular disease (CVD), anemia and proteinuria (the presence of excessive protein in the urine). All risk factors for CKD are supported by scientific theory and have been validated by national surveys and community health studies.

"If your total score from the SCORED test is 4 or higher, it doesn't mean you have CKD, but we strongly recommend further blood testing for creatinine (a marker for impaired kidney function) and/or urine exam by a physician. Similarly, having a low score does not guarantee you are free of this disease, but it means you are likely at low risk," says Dr. Bang. (The SCORED questionnaire is available below.)

In contrast, KEEP defines high-risk individuals as those who are 18 years or older with at least one of the following: diabetes; high blood pressure; or a family history of diabetes, high blood pressure or kidney disease.

"The SCORED model seems to improve diagnostic performance because of the use of additional variables, different weights for age groups, and questions about underlying CVD. Indeed, most CKD patients die of CVD before reaching end-stage renal disease (ESRD). Currently, researchers are trying to understand a potential bi-di
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Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

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