SCORED remains the first and only scoring instrument rigorously developed by statistical modeling for general population screening, as reported one year ago -- in the Feb. 26, 2007, Archives of Internal Medicine. It employs a user-friendly questionnaire and a simple scoring system based on seven risk factors for CKD -- age, sex, hypertension, diabetes, cardiovascular disease (CVD), anemia and proteinuria (the presence of excessive protein in the urine). All risk factors for CKD are supported by scientific theory and have been validated by national surveys and community health studies.
"If your total score from the SCORED test is 4 or higher, it doesn't mean you have CKD, but we strongly recommend further blood testing for creatinine (a marker for impaired kidney function) and/or urine exam by a physician. Similarly, having a low score does not guarantee you are free of this disease, but it means you are likely at low risk," says Dr. Bang. (The SCORED questionnaire is available below.)
In contrast, KEEP defines high-risk individuals as those who are 18 years or older with at least one of the following: diabetes; high blood pressure; or a family history of diabetes, high blood pressure or kidney disease.
"The SCORED model seems to improve diagnostic performance because of the use of additional variables, different weights for age groups, and questions about underlying CVD. Indeed, most CKD patients die of CVD before reaching end-stage renal disease (ESRD). Currently, researchers are trying to understand a potential bi-di
|Contact: Andrew Klein|
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College