Navigation Links
Simple model cell is key to understanding cell complexity
Date:5/15/2008

A team of Penn State researchers has developed a simple artificial cell with which to investigate the organization and function of two of the most basic cell components: the cell membrane and the cytoplasm--the gelatinous fluid that surrounds the structures in living cells. The work could lead to the creation of new drugs that take advantage of properties of cell organization to prevent the development of diseases. The team's findings will be published later this month (late May 2008) in the Journal of the American Chemical Society.

"Many scientists are trying to understand cells by turning off genes, one at a time, and are observing the effects on cell function, but we're doing the opposite," said Associate Professor of Chemistry Christine D. Keating, who led the research. "We're starting from scratch, adding in components to find out what is needed to simulate the most basic cell functions. Our goal is to find out how much complexity can be observed in very simple collections of molecules."

Building on previous work that was published in the 16 January 2008 issue of Journal of the American Chemical Society, Keating and her colleagues built a model cell using as the cytoplasm a solution of two different polymers: polyethyleneglycol (PEG) and dextran. The researchers encapsulated this polymer solution inside a cell membrane and, because the two polymers do not mix, one of the phases surrounded the other like the white of an egg around a yolk. The team then exposed the cell to a concentrated solution of sugar. Through a process known as osmosis--in which water diffuses across a cell membrane from a region of higher water concentration to a region of lower water concentration--water traveled from the relatively diluted polymer solution inside the cell to the more concentrated sugar solution outside the cell. As a result, the volume of the polymer solution inside the membrane was reduced.

With a cell membrane that was now
'/>"/>

Contact: Barbara K. Kennedy
science@psu.edu
814-863-4682
Penn State
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Salt-tolerant gene found in simple plant nothing to sneeze at
2. Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines
3. Simple recipe turns human skin cells into embryonic stem cell-like cells
4. Simple reason helps males evolve more quickly
5. Researchers develop simple method to create natural drug products
6. Gene regulation in humans is closer than expected to simple organisms
7. Safe water: simpler method for analyzing radium in water samples cuts testing time
8. Model successfully predicts large river system fish diversity
9. Climate modelers see modern echo in 30s Dust Bowl
10. A model photochemical compass for bird navigation
11. In computer models and observations, researchers see potential for significant red tide season
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Simple model cell is key to understanding cell complexity
(Date:7/10/2014)... and teens living with a cardiac pacemaker, a low ... of life, reports a study in the July ... the official journal of the Society for Developmental ... by Lippincott Williams & Wilkins , a part ... function as a protective factor against lower health-related quality ...
(Date:7/10/2014)... image was collected by the Moderate Resolution Imaging Spectroradiometer ... Each hot spot, which appears as a red mark, ... MODIS instrument recognized temperatures higher than background. When accompanied ... hot spots are diagnostic for fire. , This ... coming directly from the fires, although the smoke released ...
(Date:7/10/2014)... some patients, the chronic inflammatory skin diseases psoriasis* and ... have therefore had to base their decision on which ... an examination of tissue samples. A team of researchers ... of Munich (TUM) have now analyzed the molecular processes ... This has enabled them for the first time to ...
Breaking Biology News(10 mins):For children with pacemakers, 'self-competence' affects quality of life 2New diagnostic test to distinguish psoriasis from eczema 2
... Science-based identification of mold and other causes of ... plant pathologists with The American Phytopathological Society (APS). ... situation in which building occupants experience health problems ... typically associated with SBS range from allergy attacks ...
... South Korean team announced last week that it had ... that were genetically matched to specific people. But their ... Yuri Verlinsky of the Reproductive Genetics Institute, based in ... without resorting to therapeutic cloning. "It would be a ...
... When genes are deleted on a particular section of ... the childhood cancer neuroblastoma. A new study suggests that ... children with neuroblastoma may indicate to physicians that they ... fight the cancer. , Edward F. Attiyeh, M.D., a ...
Cached Biology News:What's really making you sick? Plant pathologists offer the science behind Sick Building Syndrome 2Double triumph in stem cell quest 2Double triumph in stem cell quest 3Double triumph in stem cell quest 4Chromosome Deletion Predicts Aggressive Neuroblastoma 2
(Date:1/15/2014)... 2014 This webinar will focus on ... safety assessment in biosimilars. , Regulatory frameworks are evolving ... development, however the complex nature of biopharmaceuticals makes the ... efficacy extremely challenging. Based on the specific aspects of ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 The Microcompetition with ... major disease. One of these latent viruses is the Epstein ... arthritis (RA). Rheumatoid arthritis (RA) is a chronic inflammatory disease ... a study found that RA patients have high concentrations of ...
(Date:1/15/2014)... 15, 2014 AudioNotch is the internet's ... for the treatment of tinnitus. Patients listen to sound ... over a period of weeks to months, their tinnitus volume ... two forms: Notched Music and Notched White Noise. Now, AudioNotch ...
(Date:1/14/2014)... 2014 Histogen, Inc., a regenerative medicine ... grown under simulated embryonic conditions, today announced that they ... Medical, Inc. for physician-dispensed aesthetic products containing Histogen’s proprietary ... agreement is an amendment to the existing license between ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3
... Pharmaceutical Inc. (Nasdaq: BMRN ) today announced that ... company update at the Deutsche Bank 34th Annual Health Care ... p.m. ET. Interested parties may access a live audio ... the BioMarin website, www.BMRN.com . A ...
... platform for treatment of Spinal Muscular Atrophy SOUTH PLAINFIELD, ... Inc. (PTC) and the Spinal Muscular Atrophy (SMA) Foundation ... which the SMA Foundation will provide up to $8.5 ... second continuation of the collaboration to fund a series ...
... AND STRENGTHENS ITS SENIOR MANAGEMENT TEAM , ... Systems, Inc. (OTC Bulletin Board: OMCM.OB), a leader in ... today announced that it has strengthened its European presence ... Summa. As Executive Vice President, Europe & Asia/Pacific based ...
Cached Biology Technology:BioMarin to Present at the Deutsche Bank Health Care Conference 2PTC Therapeutics and Spinal Muscular Atrophy Foundation Announce $8.5 Million Small Molecule Development Collaboration 2PTC Therapeutics and Spinal Muscular Atrophy Foundation Announce $8.5 Million Small Molecule Development Collaboration 3OmniComm Systems Appoints EDC Veteran Dr. Wolfgang Summa to Executive Vice President, Europe & Asia/Pacific 2OmniComm Systems Appoints EDC Veteran Dr. Wolfgang Summa to Executive Vice President, Europe & Asia/Pacific 3
... Glutathion-S-Transferase-pi EIA Principle: Glutathion-S-transferases ... which are involved in the detoxification ... 5 subgroups: Alpha, Mu, Pi, Teta ... their physiochemical, immunological, enzymatic and s ...
... only microplate sealer with an integrated in-line ... with a variety of configurations and sealing ... integrated stacker and 240-plate storage capacity , ... in small workcells , Handles all SBS ...
... aptamer screening and binding optimization and built ... on-chip synthesis platform. These microarrays are available ... Microarray Service. Probe Content ... than 1500 known aptamer sequences. Add up ...
... Microarrays designed for RNA aptamer screening and ... and powerful Paraflo microfluidic on-chip synthesis platform. ... be synthesized on-chip and LC Sciences can ... microarrays are available as part of our ...
Biology Products: