Navigation Links
Simple gut hormone combo makes our brains think we're full
Date:10/25/2011

Many of us would love nothing more than to trick ourselves into believing we are full even as our stomachs remain empty. Now, a new brain imaging study reported in the November issue of the Cell Press journal Cell Metabolism suggests there might just be a way. The key is to go with our guts just two gut hormones, that is.

The findings suggest that a simple hormone-inspired pill could be the long-sought answer to healthy eating, according to the researchers.

"Obesity is a major and rising problem," said Waljit Dhillo of Imperial College London. "The central dogma is we need to eat less, but that doesn't work so well. Understanding how the brain makes us feel hungry and full is an important issue for therapy."

As lunchtime approaches, our brains get excited at the very thought of that next meal, Dhillo explained. After we've eaten, the same foods that seemed so tempting to us in our hunger lose their sway.

The gut hormones peptide YY (PYY) and glucagon-like peptide 1 (GLP-1), which are both released into circulation after we eat, are known to play some role in that process. Studies in which people have been given one or the other of those hormones show a reduction in food intake and appetite. Still, no one knew what kind of influence those hormones really have on our brains.

Dhillo's team of scientists from Imperial College and GlaxoSmithKline used functional magnetic resonance imaging (fMRI) to measure brain activity in healthy people after they'd been given PYY and/or GLP-1 in a fasted state. Those scans were compared to the brains of those same individuals when they were full from eating a standard meal.

After a meal, people's brains responded less to images of food in regions related to food reward, and they ate less. A very similar thing happens to the brains and behaviors of hungry people after they've taken PYY and GLP-1 in combination.

"Participants had eaten no breakfast, but the
'/>"/>

Contact: Lisa Lyons
elyons@cell.com
617-386-2121
Cell Press
Source:Eurekalert

Page: 1 2

Related biology news :

1. Diversity of trees in Ecuadors Amazon rainforest defies simple explanation
2. Simple chemical procedure augments therapeutic potential of stem cells
3. A simple fusion to jump-start evolution
4. Artificial cells, simple model for complex structure
5. Simple test helps predict heart attack risk
6. Pitt-led researchers create quick, simple fluorescent detector for TB
7. Author says challenging simple concepts can save planet
8. Simple drug treatment may prevent nicotine-induced SIDS: Study
9. New blood tests promise simple, cost-effective diagnosis of gastrointestinal cancers
10. Scientists take step toward simple and portable tuberculosis tests for developing world
11. Simple test could offer cheap solution to detecting landmines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Colo., USA - The rise of the Tibetan plateau ... Earth -- is important for both its profound effect ... this study published in GSA Bulletin , Katharine ... "clumped" isotope thermometry -- using modern and fossil snail ... basin in southwestern Tibet. , Views range widely ...
(Date:8/28/2014)... news release is available in German . ... water fish, owes its name to a striking pattern of ... types, black cells, reflective silvery cells, and yellow cells emerge ... and arrange as a multilayered mosaic to compose the characteristic ... three cell types have to interact to form proper stripes, ...
(Date:8/28/2014)... (Maximizing Access to Research Careers) Program has announced ... of America,s 27th Annual Mouse Molecular Genetics Conference ... Pacific Grove, California. These awards are meant ... and scientists from underrepresented groups into the mainstream ... the participation of young scientists at the Genetics ...
Breaking Biology News(10 mins):Snails tell of the rise and fall of the Tibetan Plateau 2Snails tell of the rise and fall of the Tibetan Plateau 3Snails tell of the rise and fall of the Tibetan Plateau 4Snails tell of the rise and fall of the Tibetan Plateau 5Snails tell of the rise and fall of the Tibetan Plateau 6Snails tell of the rise and fall of the Tibetan Plateau 7How the zebrafish gets its stripes 2How the zebrafish gets its stripes 3
... researchers in collaboration with researchers at Rutgers University ... first step in carrying out instructions contained in ... in the Nov. 17 issue of the journal ... of DNA during transcription and the effects of ...
... of medical and biological research are abuzz with ... dots. These Quantum Dots (QDs) have unique optical ... breakthrough treatments such as the detection and destruction ... website AZoNano, is a comprehensive review of the ...
... before undergoing surgery run an increased risk of ... pulmonary embolism after surgery. , Boris Mraovic, M.D., ... Center at Jefferson Medical College of Thomas Jefferson ... of nearly 6,500 hip or knee replacement surgery ...
Cached Biology News:UCLA researchers unravel a mystery about DNA 2Jefferson scientists find high glucose before surgery raises risk of dangerous complications 2
(Date:8/28/2014)... The ability for organizations to attract top ... individuals to perform at the highest of levels, are ... to compete in this post–recession era. The pharmaceutical ... the sector increasingly focuses on the importance of employee-fit ... real results on the organization's development and the innovation ...
(Date:8/28/2014)... --  SunTrust Robinson Humphrey (STRH) today announced ... equity research team in biotechnology and oilfield services.  ... research demonstrates our commitment to providing our valued ... investment decision making," said Biff Woodruff , ... make significant investments in differentiated content at a ...
(Date:8/28/2014)... MENLO PARK, Calif. , Aug. 28, 2014 ... company focused on developing novel mid- to late-stage ... raised $7.0 million in its first round of ... AshHill Biomedical Investments and Hercules Bioventures with participation ... biotech entrepreneur and pharmaceutical executive, Dr. Larry ...
(Date:8/28/2014)... Scientists, researchers, and technologists will converge ... Damage 2014 symposium. Marking its 46th year, the ... run 14-17 September. The event is sponsored by ... , The premier conference for basic and applied issues ... materials will engage researchers and engineers from numerous industries ...
Breaking Biology Technology:Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 2SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 3Armetheon Completes $7.0 Million Series A Financing 2Armetheon Completes $7.0 Million Series A Financing 3Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 2Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 3
... 18 Burrill & Company, a San Francisco-based global ... Private Equity, Merchant Banking and Media, is pleased to ... Managing Director, Merchant Banking. Shawn will assist clients in ... raising transactions. In addition, Shawn will make an important ...
... LONDON, June 18 , ... UK Distribution Rights , Speciality ... pharmaceutical company, is pleased to announce that it will ... the,UK and Ireland, as of the 1st July 2009. ...
... of Oregon physicists have successfully landed a one-two punch ... helium and then dosing its perimeter with a laser ... a near standstill. The findings, published in ... that exploits special quantum properties and in precision-measurements for ...
Cached Biology Technology:Shawn Cross Joins Burrill Merchant Banking 2Shawn Cross Joins Burrill Merchant Banking 3SEP Signs REGURIN(R) Deal 2SEP Signs REGURIN(R) Deal 3SEP Signs REGURIN(R) Deal 4SEP Signs REGURIN(R) Deal 5SEP Signs REGURIN(R) Deal 6
Ethylene glycol-bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid, Molecular Biology Grade...
Ethylene glycol-bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid...
Kit Components: Anti-PARP LumiGLO Chemiluminescent Substrate Immunoblot Blocking Reagent Pyronin Y Reagent Goat Anti-Rabbit IgG, HRP conjugate Double-It Reagent Film Exposure Folders Autor...
ssDNA from PCR DNA in less than 1 hour. No gels, columns, or slurries. Sequence from high quality ssDNA: clearer reads, longer runs....
Biology Products: