Navigation Links
Simple drug treatment may prevent nicotine-induced SIDS: Study
Date:6/3/2009

in.

"The result is like trying to drive your car with the parking brake on. You might go a little bit, but the brakes hold you back," explains Buttigieg. "In this case, the adrenal glands do not release catecholamines during hypoxia for example during birth or a self-asphyxiation episodeoften resulting in death."

But when researchers administered the drug glibenclamide in laboratory rats, which override the brake protein, the adrenal glands were able to respond to oxygen deprivation, therefore reversing the lethality of hypoxia.

"Our initial goal was really to understand how the nervous system regulates oxygen sensitivity of cells in the adrenal gland at a basic research level," says Colin Nurse, academic advisor on the study and a professor in the department of Biology. "We speculated that chemicals released from nerves might interact with adrenal cells and cause them to lose oxygen sensitivity. It turns out that nicotine mimics the effects of one of these chemicals, thereby allowing us to test the idea. The present study was significant in that it led to a mechanistic understanding of how nicotine works in this context."


'/>"/>

Contact: Michelle Donovan
donovam@mcmaster.ca
905-304-1433
McMaster University
Source:Eurekalert

1

GOOD

Page: 1 2

Related biology news :

1. Safe water: simpler method for analyzing radium in water samples cuts testing time
2. Gene regulation in humans is closer than expected to simple organisms
3. Researchers develop simple method to create natural drug products
4. Simple reason helps males evolve more quickly
5. Simple recipe turns human skin cells into embryonic stem cell-like cells
6. Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines
7. Salt-tolerant gene found in simple plant nothing to sneeze at
8. Simple model cell is key to understanding cell complexity
9. Research measures movement of nanomaterials in simple model food chain
10. Genome of simplest animal reveals ancient lineage, confounding array of complex capabilities
11. At risk for peripheral arterial disease? Simple quiz provides key so you can circulate better
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2009)... Spanish and American researchers found the fossil remains of a ... have published, for the first time, the results of the ... the young cetacean, possibly a baleen whale from the Mysticeti ... partial fossil remains of a whale from the Lower Pliocene ... but it is the first time that the results of ...
(Date:12/15/2009)... 15 The PTR Group, a leading real-time ... it has agreed to sponsor three high school teams ... Competition ( http://usfirst.org ). ,, The PTR ... in three different states. The teams from Atholton ... and James Madison HS in Vienna, VA all have ...
(Date:12/14/2009)... touching, or for Tasmanian devils biting each ... driven the dinosaurs to extinction through the transmission of ... f1000 Biology, highlights the ,paleobiological detective work, of David ... them to deduce that a protozoan parasite was to ... tyrannosaurid fossils. , The parasite,s modern-day equivalent, which infects ...
Breaking Biology News(10 mins):Story of 4.5 million-year-old whale unveiled in Huelva 2Story of 4.5 million-year-old whale unveiled in Huelva 3The PTR Group Announces Financial and Technical Support to US FIRST Robotics Competition Teams 2Davis Vision United Concordia Dental and The Pittsburgh Pirates Team Up to Provide Free Dental and Vision Screenings 49665 1Davis Vision United Concordia Dental and The Pittsburgh Pirates Team Up to Provide Free Dental and Vision Screenings 49665 2Davis Vision United Concordia Dental and The Pittsburgh Pirates Team Up to Provide Free Dental and Vision Screenings 49665 3On HIV Testing Day HIVMA calls for health care reform to make testing routine every day 49660 1On HIV Testing Day HIVMA calls for health care reform to make testing routine every day 49660 2HIV Atlas Shows Virus Targeting Minorities 49655 1HIV Atlas Shows Virus Targeting Minorities 49655 2HIV Atlas Shows Virus Targeting Minorities 49655 3
... fluids is the standard emergency treatment in the ... UC San Diego bioengineering researchers have reported improved ... earlier studies in humans that have shown benefits ... than normal saline, the researchers combined hypertonic saline ...
... Hoenig and Aaron Welch, both graduate students at ... Marine UM Rosenstiel School students take home top ... Science, won first place in the High-Potential Venture ... Entrepreneurship Competition. The two Marine Affairs and ...
... bring together energy leaders, industry professionals and academicians representing ... North American Energy Summit (NAES) May 1-2 in the ... summit will feature experts with diverse backgrounds from the ... for future generations. , Distinguished guests include The ...
Other Biology News:Hyperviscous fluids: Better treatment for severe blood loss 2Hyperviscous fluids: Better treatment for severe blood loss 3Hyperviscous fluids: Better treatment for severe blood loss 4Aquaculture concept leaves judges 'goggle eyed' 2UTSA hosts North American Energy Summit May 1-2 2
(Date:12/15/2009)... (JBEI), one of three Department of Energy (DOE) bio-energy ... to protect its valuable intellectual property. , ... ... 15, 2009 -- Surety, LLC , the leading ... announced that the Joint BioEnergy Institute (JBEI), one of ...
(Date:12/15/2009)... Va., Dec. 15 AstraZeneca (NYSE: ... of Virginia (UVa) in Charlottesville, today announced ... research collaboration to enhance development of new ... with a secondary focus on peripheral vascular ... ) ,, The collaborative preclinical research projects ...
(Date:12/15/2009)... N.Y., Dec. 15 On January 20th, ... Society for Medical Publication Professionals (ISMPP) will be ... London, UK. More than 100 attendees are expected ... for publication professionals, editors, publishers, medical writers and ... medical publications and the impact of guidelines and ...
(Date:12/14/2009)... Vermillion, Inc. (Pink Sheets: VRML), a molecular ... Ph.D. Chief Scientific Officer, Senior Vice President, ... be joining its board of directors upon ... "Bill brings more than 20 years research ... said Gail Page, Vermillion Executive Chairperson. ...
Breaking Biology Technology:Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 2Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 3Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 4Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 5AstraZeneca and the University of Virginia Sign Strategic Research Collaboration to Develop Novel Treatments for Cardiovascular Disease 2AstraZeneca and the University of Virginia Sign Strategic Research Collaboration to Develop Novel Treatments for Cardiovascular Disease 3Announcing ISMPP EU 2010 - the First European Meeting of the International Society for Medical Publication Professionals, Royal College of Physicians, London, UK, January 20, 2010 2Vermillion Announces Appointment of William C. Wallen, Ph.D. to Board of Directors 2Vermillion Announces Appointment of William C. Wallen, Ph.D. to Board of Directors 3Vermillion Announces Appointment of William C. Wallen, Ph.D. to Board of Directors 4
... Md., May 28 GenVec, Inc. (Nasdaq: ... agreement with a single institutional investor for the sale of 9,615,385 ... of its common stock. The shares of common stock and ... common stock and a warrant to purchase one share of common ...
... Proteon also receives orphan drug designation for its lead ... Inc., announced today that it has completed a second ... additional $12 million and increasing the total equity capital ... equity investment came primarily from two new investors, Bessemer ...
... Chinese Academy of Sciences in Beijing, scientists have investigated ... understand how they may help in the development of ... The research focused on rotating magnetic fields, which play ... generators. The difficulty for technology at the atomic scale ...
Other Biology Technology:GenVec Announces Registered Offering of $6 Million in Common Stock and Warrants 2GenVec Announces Registered Offering of $6 Million in Common Stock and Warrants 3Proteon Therapeutics Completes Second Closing of Equity Financing; Raises Total Series B to $50 million 2
... comes with a shutter (controlled via a TTL ... The DH-2000 Deuterium Tungsten Halogen Light ... tungsten halogen light sources in a single optical ... stable output from 215-200 nm. In addition, deep-UV ...
... Analysis Note: Agglutination activity is expressed in g ... in phosphate buffered saline, pH 6.8, of a ... activity is the lowest concentration to agglutinate a ... after 1 hour incubation at 25 C. ...
... Security ChemStation is a ... application for data acquisition, ... searching and reporting, addressing ... data security, integrity, and ...
... These handy dispensers save ... glasses, wipers, hats, and other ... benchtop storage bins for small ... and manufacturing. Clear acrylic. Open-slot ...
Biology Products: