Navigation Links
Simple blood test in the first trimester predicts fetal gender
Date:1/3/2012

Bethesda, MDA new research study published in the January 2012 edition of The FASEB Journal (http://www.fasebj.org) describes findings that could lead to a non-invasive test that would let expecting mothers know the sex of their baby as early as the first trimester. Specifically, researchers from South Korea discovered that various ratios of two enzymes (DYS14/GAPDH), which can be extracted from a pregnant mother's blood, indicate if the baby will be a boy or a girl. Such a test would be the first of its kind.

"Generally, early fetal gender determination has been performed by invasive procedures such as chorionic villus sampling or amniocentesis. However, these invasive procedures still carry a one to two percent risk of miscarriage and cannot be performed until 11 weeks of gestation. Moreover, reliable determination of fetal gender using ultrasonography cannot be performed in the first trimester, because the development of external genitalia is not complete," said Hyun Mee Ryu, M.D., Ph.D., a researcher involved in the work from the Department of Obstetrics and Gynocology at Cheil General Hospital and Women's Healthcare Center at the KwanDong University School of Medicine in Seoul, Korea. "Therefore, this can reduce the need for invasive procedures in pregnant women carrying an X-linked chromosomal abnormality and clarify inconclusive readings by ultrasound."

To make this discovery, Ryu and colleagues collected maternal plasma from 203 women during their first trimester of pregnancy. The presence of circulating fetal DNA was confirmed by a quantitative methylation-specific polymerase chain reaction of U-PDE9A. Multiplex real-time polymerase chain reaction was used to simultaneously quantify the amount of DYS14 and GAPDH in maternal plasma. The results were confirmed by phenotype at birth.

"Although more work must be done before such a test is widely available, this paper does show it is possible to predict the sex of a child as early as the first few weeks after conception," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "At present, parents are sometimes given the wrong information about the sex of their unborn child; this test should prove helpful in resolving any uncertainties of today's ultrasound observations."


'/>"/>
Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related biology news :

1. Diversity of trees in Ecuadors Amazon rainforest defies simple explanation
2. Simple chemical procedure augments therapeutic potential of stem cells
3. A simple fusion to jump-start evolution
4. Artificial cells, simple model for complex structure
5. Simple test helps predict heart attack risk
6. Pitt-led researchers create quick, simple fluorescent detector for TB
7. Author says challenging simple concepts can save planet
8. Simple drug treatment may prevent nicotine-induced SIDS: Study
9. New blood tests promise simple, cost-effective diagnosis of gastrointestinal cancers
10. Scientists take step toward simple and portable tuberculosis tests for developing world
11. Simple test could offer cheap solution to detecting landmines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... , Feb. 5, 2016 ... addition of the "Global Facial Recognition ... --> http://www.researchandmarkets.com/research/5kvw8m/global_facial ) has announced ... Recognition Market 2016-2020" report to their ... ( http://www.researchandmarkets.com/research/5kvw8m/global_facial ) has announced the addition ...
(Date:2/3/2016)... 3, 2016 Vigilant Solutions announces today that ... Missouri solved two recent hit-and-run ... data from Vigilant Solutions. Brian Wenberg ... the victim was walking out of a convenience store and witnessed an elderly ... his vehicle, striking his vehicle and leaving the scene.  ...
(Date:2/2/2016)... 2, 2016 Checkpoint Inhibitors for Cancer ... Are you interested in the future of ... checkpoint inhibitors. Visiongain,s report gives those predictions to ... national level. Avoid falling behind in data ... and revenues those emerging cancer therapies can achieve. ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... Inc. (NYSE: DPLO) announced today that its new website has gone live. On Thursday, Feb. 4, ... Visit the new site: www.diplomat.is ... ... ... "The goal was to reimagine the website and create a smarter, ...
(Date:2/5/2016)... , Feb. 5, 2016  In the pharmaceutical industry ... a host of launch activities including the identification and ... launch activity is especially high in the oncology therapeutic ... Best Practices and the Role of Medical Affairs in ... focused on oncology therapies find better ways to utilize ...
(Date:2/4/2016)... New FDA action date of July 22, 2016   ... 22, 2016   --> - New FDA ... - Lifitegrast has the potential to be the only product approved ... and symptoms of dry eye disease in adults --> - ... the U.S. in the past decade indicated for the treatment of signs and ...
(Date:2/4/2016)... N.J. , Feb. 4, 2016  CytoSorbents ... immunotherapy leader commercializing its flagship CytoSorb® blood filter ... surgery patients around the world, announced that CEO ... present at the Source Capital Group,s 2016 Disruptive ... update on the company.  Conference ...
Breaking Biology Technology: