Navigation Links
Silk-based surgical implants could offer a better way to repair broken bones
Date:3/4/2014

is that it can stabilize and deliver bioactive components, so that plates and screws made of silk could actually deliver antibiotics to prevent infection, pharmaceuticals to enhance bone regrowth and other therapeutics to support healing," says Kaplan.

Kaplan and his team have previously developed silk-based sponges, fibers and foams for use in the operating room and in clinical settings. But until now, silk hadn't been used in the development of a solid medical device for fracture fixation.

The Tufts researchers used silk protein obtained from Bombyx mori (B. mori) silkworm cocoons to form the surgical plates and screws. Produced from the glands of the silkworm, the silk protein is folded in complex ways that give it unique properties of both exceptional strength and versatility.

To test the new devices, the investigators implanted a total of 28 silk-based screws in six laboratory rats. Insertion of screws was straightforward and assessments were then conducted at four weeks and eight weeks, post-implantation.

"No screws failed during implantation," says Kaplan, explaining that because silk is slow to swell, the new devices maintained their mechanical integrity even when coming into contact with fluids and surrounding tissue during surgery. The outcomes suggest that the use of silk plates and screws can spare patients the complications that can develop when metal or synthetic polymer devices come into contact with fluids.

"Having a resorbable, long-lasting plate and screw system has potentially huge applications," says Lin. While the initial aim is to use silk-based screws to treat facial injuries, which occur at a rate of several hundred thousand each year, the devices have the potential for the treatment of a variety of different types of bone fractures.

"Because the silk screws are inherently radiolucent [not seen on X-ray] it may be easier for the surgeon to see how the fracture is pro
'/>"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. National Robotics Initiative grant to create smarter surgical robots
2. Non-Surgical Procedures are Now Available at a Discount at Strax Rejuvenation
3. Nonsurgical treatment turns back the clock, shrinks enlarged prostate
4. Medical societies unite on patient-centered measures for nonsurgical stroke interventions
5. Surgical Theater, LLC sells first Surgical Rehearsal Platform to UH Case Medical Center
6. Pre-surgical steps for eye surgery are standardized through JoVEs video publication
7. Researchers discover non-surgical test for brain cancer
8. Global Surgical Devices Market Growth Driven by Improving Standards of Living and Longer Life Expectancies, Research Shows
9. Cochlear implants -- with no exterior hardware
10. Study finds natural compound can be used for 3-D printing of medical implants
11. New research association started: Magnesium implants shall facilitate bone fracture healing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... identity analyst firm Acuity Market Intelligence forecasts that in ... have a chip-based National eID card, including near-complete regional ... Asia , with its vast population, is expected ... of all National eID cards issued between 2014 and ... National eID Industry Report: 2014 Edition" — projects ...
(Date:10/18/2014)... a group of 2,000 patients referred for evaluation ... potential molecular diagnosis for 25 percent, including detection ... new mutations contributing to disease, according to a ... is being released to coincide with the American ... sequencing analyzes the exons or coding regions of ...
(Date:10/17/2014)... for the first time how bacteria can grow directly ... the opportunity to get tremendous insights into bacteria behavior ... discovered the bacterial growth in chronic lung infections among ... by the immune cells. The researchers discovered the immune ... bacteria, forcing the bacteria to switch to a much ...
Breaking Biology News(10 mins):Half the World's Population Will Have Chip-Based National Electronic Identity (eID) Cards by 2018 2Whole-exome sequencing shows potential as diagnostic tool 2Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2
... Panama Canal in a Boston Whaler may sound like the ... story brandishes a butterfly net and studies the effects of ... Institute. , "Our long-term study shows that El ... Robert Srygley, former Smithsonian post doctoral fellow who is now ...
... is available in Spanish . , Individuals ... nuts, whole grains and fish- appear less likely to develop ... published in the October issue of Archives of General ... been found to be lower in Mediterranean than Northern European ...
... 09, 2009) -- According to new research from the Monell ... herbicides and lipid-lowering fibrate drugs act in humans to block ... pancreas. Commonly used in agriculture and medicine, these ... T1R3 receptor. The T1R3 receptor is a critical ...
Cached Biology News:Panama butterfly migrations linked to El Nio, climate change 2Mediterranean diet associated with reduced risk of depression 2Common herbicides and fibrates block nutrient-sensing receptor found in gut and pancreas 2
(Date:10/22/2014)... Oct. 22, 2014 Research and ... "Global DNA Diagnostics Market (Product types, Application, ... Global Trends, Company Profiles, Demand, Insights, Analysis, Research, ... report to their offering. ... applications, techniques, end users and Geography) Global Size, ...
(Date:10/22/2014)... October 22, 2014 Involution Studios ... release of a new infographic, Understanding Ebola . ... a beautifully designed, easy to follow informative tool for ... of outbreak, symptoms and prevention. , "As the news ... the 2014 Ebola outbreak represents not only a healthcare ...
(Date:10/22/2014)... According to new market research ... (Consulting, Integration, Deployment & Support), by Service Model ... Private, Others (Hybrid & Community)) - Global Forecast ... the Cloud Professional Services Market into various sub-segments ... It also identifies the drivers and restraints for ...
(Date:10/22/2014)... KONG , Oct. 22, 2014  aTyr Pharma ... that rare disease expert John C. McKew , ... McKew brings more than two decades of expertise in ... Institutes of Health, Wyeth Research and Genetics Institute, Inc. ... aTyr,s efforts to expand and translate its novel Physiocrine ...
Breaking Biology Technology:Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 2Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 3Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3
... State agencies have backed a new organization, ... with early-stage companies. , ,Wisconsin excels in researching and ... investment in the first and most critical stage, said ... formation on Tuesday. , ,The Wisconsin Technology Council ...
... made Computerworld magazines recently released list of ... , , Christopher A. Graham, vice president and CIO of ... provides insurance plans to religious organizations, including churches as well ... clients across all 50 states. , , Herman Nell, senior ...
... College recently finished the first semester of its ... will soon be taught at technical colleges all over ... for security specialists. , ,MATC, one of the largest ... degree development process down to five months. Network security, ...
Cached Biology Technology:Computerworld: Three Wisconsin CIOs among top 100 IT leaders 2MATCs new computer security program gears up for second semester 2MATCs new computer security program gears up for second semester 3
... siSolutions siRNA Custom Synthesis ... effective duplex RNA to knockdown ... 21-mers (19 RNA base pairs ... recently-published 27-mers, or other lengths ...
Alexa Fluor 647 anti-mouse Qa-2...
...
Alexa Fluor 647 anti-mouse Qa-2...
Biology Products: