Navigation Links
Silk-based surgical implants could offer a better way to repair broken bones
Date:3/4/2014

MEDFORD/SOMERVILLE, MASS. AND BOSTON -- When a person suffers a broken bone, treatment calls for the surgeon to insert screws and plates to help bond the broken sections and enable the fracture to heal. These "fixation devices" are usually made of metal alloys.

But metal devices may have disadvantages: Because they are stiff and unyielding, they can cause stress to underlying bone. They also pose an increased risk of infection and poor wound healing. In some cases, the metal implants must be removed following fracture healing, necessitating a second surgery. Resorbable fixation devices, made of synthetic polymers, avoid some of these problems but may pose a risk of inflammatory reactions and are difficult to implant.

Now, using pure silk protein derived from silkworm cocoons, a team of investigators from Tufts University School of Engineering and Beth Israel Deaconess Medical Center (BIDMC) has developed surgical plates and screws that may not only offer improved bone remodeling following injury, but importantly, can also be absorbed by the body over time, eliminating the need for surgical removal of the devices.

The findings, demonstrated in vitro and in a rodent model, are described in the March 4 issue of Nature Communications.

"Unlike metal, the composition of silk protein may be similar to bone composition," says co-senior author Samuel Lin, MD, of the Division of Plastic and Reconstructive Surgery at BIDMC and Associate Professor of Surgery at Harvard Medical School. "Silk materials are extremely robust. They maintain structural stability under very high temperatures and withstand other extreme conditions, and they can be readily sterilized."

Collaborating with Lin were co-senior author and Tufts chair of biomedical engineering David Kaplan, PhD, a leader in the use of silk for biomedical applications, and a team of biomedical and mechanical engineers.

"One of the other big advantages of silk
'/>"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. National Robotics Initiative grant to create smarter surgical robots
2. Non-Surgical Procedures are Now Available at a Discount at Strax Rejuvenation
3. Nonsurgical treatment turns back the clock, shrinks enlarged prostate
4. Medical societies unite on patient-centered measures for nonsurgical stroke interventions
5. Surgical Theater, LLC sells first Surgical Rehearsal Platform to UH Case Medical Center
6. Pre-surgical steps for eye surgery are standardized through JoVEs video publication
7. Researchers discover non-surgical test for brain cancer
8. Global Surgical Devices Market Growth Driven by Improving Standards of Living and Longer Life Expectancies, Research Shows
9. Cochlear implants -- with no exterior hardware
10. Study finds natural compound can be used for 3-D printing of medical implants
11. New research association started: Magnesium implants shall facilitate bone fracture healing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... From AGU,s blogs: Earthquake rupture through a U.S. suburb ... University of California Davis in the hours and days ... helping scientists understand why the earthquake caused so much ... The Trembling Earth blog, hosted by the American Geophysical ... Future Mars Rovers: The Next Places to Direct Our ...
(Date:9/2/2014)... September 3, The Field Museum will present the prestigious ... of his commitment to biodiversity conservation awareness. The Parker/Gentry ... an outstanding individual, team or organization whose efforts have ... natural heritage and whose actions can serve as a ... of Mongabay.com, an environmental science and conservation news website ...
(Date:9/2/2014)... Konservat-Lagersttte of lithographic limestone is well known as ... from that area (for example, Archaeopteryx). Now, for ... in the French equivalent of these outcrops - ... oldest known water treader. , Despite the abundance ... fossils have been obtained from the Late Kimmeridgian ...
Breaking Biology News(10 mins):This week From AGU: California earthquake, future Mars rovers, models underestimate ozone 2Exceptionally well preserved insect fossils from the Rhône Valley 2
... toward EAC standard by providing ... a single platform, DALLAS, Sept. 10 As ... globe, many seek a method,to deploy border security capabilities ... ENTU ) and 3M (NYSE: MMM ),announce ...
... ,Empowering People & Commerce, WALL, N.J., Sept. ... a leader in finger-based biometric,identification and wireless public ... 2008 Biometric Technology Expo, to be held in,conjunction ... 23 - 25 at the Tampa Convention Center ...
... been awarded $1 million from the US Department of ... conversion technologies. The grant is one of six awarded ... their advanced biofuels projects. In total, the DOE will ... for their research into how non-food feedstocks can be ...
Cached Biology News:Entrust, 3M Collaborate to Provide End-to-End Secure ePassport Solution 2Entrust, 3M Collaborate to Provide End-to-End Secure ePassport Solution 3Entrust, 3M Collaborate to Provide End-to-End Secure ePassport Solution 4BIO-key(R) to Showcase Biometric Security Applications at 2008 Biometric Technology Expo 2BIO-key(R) to Showcase Biometric Security Applications at 2008 Biometric Technology Expo 3Stevens awarded $1M for advanced biofuels research 2
(Date:9/2/2014)... Opertech Bio, Inc., a company ... effective approach to sensory evaluation, today announced the ... U.S. Patent and Trademark Office, encompassing high-throughput sensory ... “Opertech’s taste evaluation technology called Microtiter Operant Gustometer ... system for rapid characterization of taste sensory properties,” ...
(Date:9/2/2014)... 2014  Synthetic Biologics, Inc. (NYSE MKT: SYN), ... candidates targeting specific pathogens that cause serious infections ... final preclinical toxicology study of SYN-004. Per U.S. ... study was required to move the Company,s lead ... devastating effects of Clostridium difficile (C. difficile), ...
(Date:9/2/2014)... 2014 Culot brings life science ... management services  BioData, producer of Labguru, the ... announce the appointment of Louis Culot as ... VP Marketing and Business Development at BioDiscovery Inc., developer ... applications. Previously, Culot worked for 17 years ...
(Date:9/1/2014)... The Collaborative R&D Terms and ... comprehensive understanding and unprecedented access to the collaborative ... worlds leading life science companies. , The report ... and why companies enter collaborative R&D deals. , ... deals terms provides critical insight into the negotiation ...
Breaking Biology Technology:Opertech Bio Receives U.S. Patent for High-Throughput Taste Evaluation Technology 2Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 2Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 3Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 4Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 5Louis Culot Appointed as BioData's CEO 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 3Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 4
... Axial Biotech, Inc., a company,revolutionizing spine care ... technologies, announced today that it has met several,major ... genetic,prognostic test for Adolescent Idiopathic Scoliosis (AIS) and ... B financing. The Series B financing was,led by ...
... The rating,agency Moody,s has raised the rating ... "Outlook stable"., As a result, the Group,s ... are substantially enhanced. Moody,s justifies,this step by reference ... of successful acquisitions and in view of the ...
... Conference Call/Webcast to be Wednesday, March 19 at 10:00 ... Emisphere,Technologies, Inc. (Nasdaq: EMIS ) will host a ... and year ended December 31,2007 on Wednesday, March 19, ... the conference call can be accessed through the,company,s Web ...
Cached Biology Technology:Axial Biotech Meets Major Scientific Milestones; Receives $6 Million Tranche of Series B Financing 2Moody's Raises Rating for Gerresheimer 2Emisphere Technologies, Inc. Announces Conference Call for 2007 Fourth Quarter and Year End Financial Results 2
biotin-4-fluorescein...
Human IL-17D Affinity Purified Polyclonal Ab...
Agar, 5 lb. Bacteriological.Moisture: < 10%, ash: < 6.5%. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
BBS/Glycerol/Casein Block and Diluent - 10X Concentrate, 1 L...
Biology Products: