Navigation Links
Signaling pathway for ginsenoside Rb1 promoting hippocampal neuronal neurite outgrowth
Date:7/15/2014

The main pathological changes of Alzheimer's disease (AD) include amyloid-beta protein-induced hippocampal neuronal injury and neurite outgrowth impairment. Phosphatidylinositol 3-kinase (PI3K)/Akt pathway and mitogen-activated protein kinase (MAPK) pathway are the important signaling pathways respectively responsible for regulating synaptic plasticity and neuronal survival. In view of the fact that ginsenoside Rb1 exhibits anti-aging and anti-dementia effects, Prof. Qionglan Yuan and her team, Department of Anatomy & Neurobiology, Tongji University School of Medicine, Shanghai, China performed a study, in which ginsenoside Rb1 was used, and found that ginsenoside Rb1 promoted hippocampal neuronal neurite outgrowth and protected against neurotoxicity induced by amlyloid-beta (23-25) via a mechanism involving Akt and extracellular signal-regulated kinase 1/2 signaling. Related results were published in Neural Regeneration Research (Vol. 9, No. 9, 2014).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. To drive infections, a hijacking virus mimics a cells signaling system
2. Scientists tie DNA repair to key cell signaling network
3. Ion selectivity in neuronal signaling channels evolved twice in animals
4. Researchers describe new molecular interactions behind the inhibition of TGF beta-signaling
5. Cholesterol helps regulate key signaling proteins in the cell
6. Waste removal in worms reveals new mechanism to regulate calcium signaling
7. FASEB SRC announces conference registration open for: Histone Deacetylases, Sirtuins, and Reversible Acetylation in Signaling and Disease
8. FASEB SRC announces conference registration open for: NAD Metabolism & Signaling
9. FASEB SRC announces conference: TGF-β Superfamily: Signaling in Development & Disease
10. Signaling pathway linked to fetal alcohol risk
11. Structure of cell signaling molecule suggests general on-off switch
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Signaling pathway for ginsenoside Rb1 promoting hippocampal neuronal neurite outgrowth
(Date:9/30/2014)... Evidence of the environmental effects of moorland burning is ... the subject, with the aim of relieving tensions on ... , The EMBER (Effects of Moorland Burning on the ... burning on moorland, which is practised predominantly to support ... impacts on peat hydrology, peat chemistry and physical properties, ...
(Date:9/30/2014)... monkeys have captured the popular attention of both children ... cycle -- sold as dehydrated eggs, these tiny brine ... than a tank of salt water. , Physicists, ... zooplankton, brine shrimp vertically migrate in large groups in ... surface at night and retreating deeper during the day. ...
(Date:9/30/2014)... Medicine reports positive results of a phase 1 ... of lung cancer marked by rearrangement of the gene ... advanced non-small cell lung cancer testing positive for ROS1 ... 3 complete responses and 33 partial responses. Median progression-free ... to resume its growth after being slowed by treatment ...
Breaking Biology News(10 mins):Grouse moor burning causes widespread environmental changes 2Laser-guided sea monkeys show how zooplankton migrations may affect global ocean currents 2NEJM: Crizotinib effective in Phase 1 trial against ROS1 lung cancer 2
... at the Smithsonian Institution and the Hawaii Institute of ... have created the first frozen bank for Hawaiian corals ... to preserve their diversity in Hawaii. Mary Hagedorn, an ... with the Smithsonian Conservation Biology Institute, leads the laboratory ...
... treatment, also brings debilitating side effects such as nausea, liver ... a new way to deliver this life-saving therapy to cancer ... has been invented by Dr. Dan Peer of Tel ... Center for Nano Science and Nano Technology together with Prof. ...
... More than 120 sturgeon and paddlefish scientists and enthusiasts from ... 2 in Bozeman and at Chico Hot Springs in Montana. ... North American Chapter of the World Sturgeon Conservation Society and ... in North America. The meeting will begin in Bozeman, ...
Cached Biology News:Smithsonian scientists help create first frozen repository for Hawaiian coral 2A cluster bomb for cancer care 2
(Date:10/1/2014)... BETHESDA, Md. , Oct. 1, 2014 /PRNewswire/ ... committed to the fostering and monetization of intellectual ... Spherix,s litigation against VTech and Uniden in the ... Texas has been rescheduled ... scheduled for October 2, 2014.  The Court Order ...
(Date:10/1/2014)... Irvine, CA (PRWEB) September 30, 2014 ... for user-friendly, cost-effective tools to address sales, training ... PMG has developed innovative mobile applications to ... studies, outlining the agency’s latest customized mobile app ... http://www.studiopmg.com/work . , In partnership with Toyota, ...
(Date:10/1/2014)... The U.S. Department of Labor has ... Edwardsville as part of the Trade Adjustment Assistance Community ... co-administered by the Department of Labor and Department of ... Thomas E. Perez and Secretary of Education Arne Duncan ... grants to nearly 270 colleges across the country. ...
(Date:9/30/2014)... . , Electrical ... a new kind of building block for digital integrated ... be based on three-dimensional arrangements of nanometer-scale magnets instead ... semiconductor industry CMOS fabrication of silicon chips ... the University of Notre Dame are exploring "magnetic computing" ...
Breaking Biology Technology:Markman Hearing Date for VTech and Uniden Litigation Now Set for November 10, 2014 2Digital Agency Studio PMG Launches New Case Studies on Website 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 3U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 4A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3
... Esker Software, worldwide leader in ... Esker Fax and VSI-FAX(R) product ... Notes 3.0. This new solution ... communicate more efficiently, effectively, and ...
... often encounter certain genes, chromosomal regions or entire ... CloneSmart technology was designed specifically to eliminate many ... individual gene or a complete genome. The technology ... clone sequences that are difficult to clone with ...
... Information Networks Corporation, a leading Midwest provider of data ... it has been selected by Microsoft as a featured ... Studio .NET 2003 Launch. , , ,Scheduled for ... inMilwaukee, Wisconsin, Berbee will speak in depth about addressing ...
Cached Biology Technology:Molecular Cloning Systems Gets Distributor 2
Homo sapiens MEP50 protein, mRNA...
Mouse H60 Allophycocyanin MAb (Clone 205326) ENTREZ GeneID: 15101...
RAB32, member RAS oncogene family, mRNA (cDNA clone MGC:13500 IMAGE:4280407), complete cds...
EDTA, 0.5 M solution, 100 ml. Ethylene diaminetetraacetic acid.Sterile, nuclease-free. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Biology Products: