Navigation Links
Signaling pathway for ginsenoside Rb1 promoting hippocampal neuronal neurite outgrowth
Date:7/15/2014

The main pathological changes of Alzheimer's disease (AD) include amyloid-beta protein-induced hippocampal neuronal injury and neurite outgrowth impairment. Phosphatidylinositol 3-kinase (PI3K)/Akt pathway and mitogen-activated protein kinase (MAPK) pathway are the important signaling pathways respectively responsible for regulating synaptic plasticity and neuronal survival. In view of the fact that ginsenoside Rb1 exhibits anti-aging and anti-dementia effects, Prof. Qionglan Yuan and her team, Department of Anatomy & Neurobiology, Tongji University School of Medicine, Shanghai, China performed a study, in which ginsenoside Rb1 was used, and found that ginsenoside Rb1 promoted hippocampal neuronal neurite outgrowth and protected against neurotoxicity induced by amlyloid-beta (23-25) via a mechanism involving Akt and extracellular signal-regulated kinase 1/2 signaling. Related results were published in Neural Regeneration Research (Vol. 9, No. 9, 2014).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. To drive infections, a hijacking virus mimics a cells signaling system
2. Scientists tie DNA repair to key cell signaling network
3. Ion selectivity in neuronal signaling channels evolved twice in animals
4. Researchers describe new molecular interactions behind the inhibition of TGF beta-signaling
5. Cholesterol helps regulate key signaling proteins in the cell
6. Waste removal in worms reveals new mechanism to regulate calcium signaling
7. FASEB SRC announces conference registration open for: Histone Deacetylases, Sirtuins, and Reversible Acetylation in Signaling and Disease
8. FASEB SRC announces conference registration open for: NAD Metabolism & Signaling
9. FASEB SRC announces conference: TGF-β Superfamily: Signaling in Development & Disease
10. Signaling pathway linked to fetal alcohol risk
11. Structure of cell signaling molecule suggests general on-off switch
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Signaling pathway for ginsenoside Rb1 promoting hippocampal neuronal neurite outgrowth
(Date:7/20/2017)... July 20, 2017 Delta (NYSE: DAL ) customers ... Delta aircraft at Reagan Washington National Airport (DCA). ... Delta launches biometrics to board aircraft ... Delta,s biometric boarding pass ... is now integrated into the boarding process to allow eligible Delta ...
(Date:6/23/2017)... ARMONK, N.Y. and ITHACA, N.Y. ... IBM ) and Cornell University, a leader in dairy ... combined with bioinformatics designed to help reduce the chances ... breaches. With the onset of this dairy project, Cornell ... the Consortium for Sequencing the Food Supply Chain, a ...
(Date:5/23/2017)... first robotic gym for the rehabilitation and functional motor sense evaluation of ... Italy . The first 30 robots will be available from June ... . The technology was developed and patented at the IIT laboratories and ... thanks to a 10 million euro investment from entrepreneur Sergio Dompè. ... ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/10/2017)... ... 10, 2017 , ... USDM Life Sciences , the ... sciences and healthcare industries, announces a presentation by Subbu Viswanathan and Jennifer Jaye ... GxP Validation for Agile Cloud Platforms,” will present a revolutionary approach to achieving ...
(Date:10/9/2017)... , Oct. 9, 2017  BioTech Holdings ... mechanism by which its ProCell stem cell therapy ... limb ischemia.  The Company, demonstrated that treatment with ... of limbs saved as compared to standard bone ... molecule HGF resulted in reduction of therapeutic effect.  ...
(Date:10/9/2017)... ... October 09, 2017 , ... At its national board meeting in North Carolina, ... Harvard University’s Departments of Physics and Astronomy, has been selected for membership in ... team for the 2015 Breakthrough Prize in Fundamental physics for the discovery of the ...
Breaking Biology Technology: