Navigation Links
Signaling pathway for ginsenoside Rb1 promoting hippocampal neuronal neurite outgrowth

The main pathological changes of Alzheimer's disease (AD) include amyloid-beta protein-induced hippocampal neuronal injury and neurite outgrowth impairment. Phosphatidylinositol 3-kinase (PI3K)/Akt pathway and mitogen-activated protein kinase (MAPK) pathway are the important signaling pathways respectively responsible for regulating synaptic plasticity and neuronal survival. In view of the fact that ginsenoside Rb1 exhibits anti-aging and anti-dementia effects, Prof. Qionglan Yuan and her team, Department of Anatomy & Neurobiology, Tongji University School of Medicine, Shanghai, China performed a study, in which ginsenoside Rb1 was used, and found that ginsenoside Rb1 promoted hippocampal neuronal neurite outgrowth and protected against neurotoxicity induced by amlyloid-beta (23-25) via a mechanism involving Akt and extracellular signal-regulated kinase 1/2 signaling. Related results were published in Neural Regeneration Research (Vol. 9, No. 9, 2014).


Contact: Meng Zhao
Neural Regeneration Research

Page: 1

Related biology news :

1. To drive infections, a hijacking virus mimics a cells signaling system
2. Scientists tie DNA repair to key cell signaling network
3. Ion selectivity in neuronal signaling channels evolved twice in animals
4. Researchers describe new molecular interactions behind the inhibition of TGF beta-signaling
5. Cholesterol helps regulate key signaling proteins in the cell
6. Waste removal in worms reveals new mechanism to regulate calcium signaling
7. FASEB SRC announces conference registration open for: Histone Deacetylases, Sirtuins, and Reversible Acetylation in Signaling and Disease
8. FASEB SRC announces conference registration open for: NAD Metabolism & Signaling
9. FASEB SRC announces conference: TGF-β Superfamily: Signaling in Development & Disease
10. Signaling pathway linked to fetal alcohol risk
11. Structure of cell signaling molecule suggests general on-off switch
Post Your Comments:
Related Image:
Signaling pathway for ginsenoside Rb1 promoting hippocampal neuronal neurite outgrowth
(Date:9/28/2015)... 2015 Synaptics Inc. (NASDAQ: SYNA ), ... that Lenovo has selected Synaptics , Natural ID ... latest smartphone, the Vibe P1. The new Vibe ... device and provide swift access to applications and mobile ... ID FS4202 sensor solution utilizes AES256-bit encryption of the ...
(Date:9/24/2015)... , Sept. 24, 2015  EyeLock LLC, a ... showcasing its award winning and latest technology in Booth ... Anaheim, California . EyeLock,s iris authentication ... with unmatched biometric accuracy, making it the most proven ... platform uses video technology to deliver a fast and ...
(Date:9/10/2015)... This report provides detailed descriptions of the sensor types ... types that will dominate in the future. Many product ... technology hype curve in the last five years before ... all of them is the prominence of sensor options ... Sensors collect data about the physical and chemical properties ...
Breaking Biology News(10 mins):
(Date:10/13/2015)... -- PharmaCyte Biotech, Inc. (OTCQB: PMCB) shares closed at $.1035, ... average with 1,308,352 shares being traded. PMCB shares have been ... low of $.072 in September, then bouncing back to current ... due diligence will show investors in PharmaCyte Biotech, Inc. information ... using the link below at no cost. ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... and assessment of organotypic 3D cell culture models, has launched a 14 ... in their patent-pending 3D InSightâ„¢ Human Liver Microtissues. The service streamlines toxicity ...
(Date:10/13/2015)... , ... October 13, 2015 , ... ... President. Steve joins as the Pistoia Alliance continues to drive to increase the ... non-profit Pistoia Alliance is focusing its vision and expanding its work in supporting ...
(Date:10/13/2015)... Oct. 13 2015 Research and Markets( ... & Europe Markets for Bone Morphogenetic Protein Growth Factor ... offering. --> --> ... the formation of bone after a fracture. In nature, ... in the formation of the skeleton. There are twenty ...
Breaking Biology Technology: