Navigation Links
Shoe strings and egg openers
Date:11/8/2011

Photosynthesis is one of the most important biological processes. However, it is less efficient in plants than it could be. Red algae, in contrast, use a slightly different mechanism and are thus more productive. Scientists from the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, have now identified a so far unknown helper protein for photosynthesis in red algae. "We could elucidate its structure and its intriguing mechanism," says Manajit Hayer-Hartl, MPIB group leader. "Comparing its mechanism to the one in green plants could help to design more efficient plants." Their work has led to two recent publications in Nature and Nature Structural & Molecular Biology.

Green plants, algae and plankton metabolize carbon dioxide (CO2) and water into oxygen and sugar in the presence of light. Without this process called photosynthesis, today's life on earth would not be possible. The key protein of this process, called Rubisco, is thus one of the most important proteins in nature. It bonds with carbon dioxide and starts its conversion into sugar and oxygen.

Despite its fundamental importance, Rubisco is an enzyme fraught with shortcomings", says Manajit Hayer-Hartl, head of the Research Group "Chaperonin-assisted Protein Folding" at the MPIB. One of the problems is that Rubisco binds to the wrong sugar molecules that inhibit its activity. The inhibitors have to be removed by a special helper protein, called Rubisco activase. The Max Planck scientists discovered that during evolution two different Rubisco activases developed in plants and in red algae. They differ in structure and in their working mechanism.

Two ways of restoring activity

The newly discovered Rubisco activase in red algae repairs useless Rubisco proteins by pulling on one end of the protein, like someone who opens a shoe string. In doing so, the helper protein opens the active centre of Rubisco and releases the inhibitory sugar. The respective Rubisco activase in green plants works more like an egg opener, squeezing the inactive Rubisco protein and forcing it to let go of the sugar molecules. "Understanding the structure and function of the two activase helper proteins should facilitate efforts in biotechnology to generate plants and microorganisms that are able to convert more CO2 into valuable biomass than nature does," hopes Manajit Hayer-Hartl.


'/>"/>
Contact: Dr. Manajit Hayer-Hartl
mhartl@biochem.mpg.de
Max-Planck-Gesellschaft
Source:Eurekalert  

Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Shoe strings and egg openers
(Date:6/2/2016)... YORK , June 2, 2016   The Weather ... is announcing Watson Ads, an industry-first capability in which consumers ... by being able to ask questions via voice or text ... Marketers have long sought ... the consumer, that can be personal, relevant and valuable; and ...
(Date:6/1/2016)... Favorable Government Initiatives Coupled With ... Identification to Boost Global Biometrics System Market Through 2021  ... report, " Global Biometrics Market By Type, By ... 2011 - 2021", the global biometrics market is projected ... of growing security concerns across various end use sectors ...
(Date:5/20/2016)... -- VoiceIt is excited to announce its new marketing ... working together, VoiceIt and VoicePass will offer an ... slightly different approaches to voice biometrics, collaboration between ... Both companies ... "This marketing and technology partnership allows VoiceIt ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... Raleigh, NC (PRWEB) , ... June 27, 2016 ... ... a mission to bring innovative medical technologies, services and solutions to the healthcare ... development and implementation of various distribution, manufacturing, sales and marketing strategies that are ...
(Date:6/24/2016)... SAN DIEGO , June 24, 2016 /PRNewswire/ ... that more sensitively detects cancers susceptible to PARP ... individual circulating tumor cells (CTCs). The new test ... of HRD-targeted therapeutics in multiple cancer types. ... therapies targeting DNA damage response pathways, including PARP, ...
(Date:6/23/2016)... Mass. , June 23, 2016   ... development of novel compounds designed to target cancer ... napabucasin, has been granted Orphan Drug Designation from ... the treatment of gastric cancer, including gastroesophageal junction ... stemness inhibitor designed to inhibit cancer stemness pathways ...
(Date:6/23/2016)... 23, 2016  The Prostate Cancer Foundation (PCF) is pleased to ... faster cures for prostate cancer. Members of the Class of 2016 were selected ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
Breaking Biology Technology: