Navigation Links
Shift work may be associated with decreased risk of skin cancer
Date:3/2/2011

Boston, MA - Melatonin is known to have cancer-protective properties, and shift work can induce desynchrony of the circadian system, reducing melatonin production. Shift work has been thought to have important health impacts, with evidence linking shift work to an increased risk of several cancers including breast, endometrial, prostate, and colorectal, and non-Hodgkin lymphoma. In a recent study, researchers at Brigham and Women's Hospital (BWH) found that shift work may be associated with a reduced risk of skin cancer in women. These findings are published online in the Journal of the National Cancer Institute.

"Shift work has been associated with increased risk of certain cancers and chronic non-malignant diseases such as gastrointestinal disorders, cardiovascular disease, and diabetes," said lead study author Eva Schernhammer, MD, DrPh, a researcher in the Channing Laboratory at BWH. "However, while shift work has been associated with other cancers, the risk of skin cancer among night-shift workers is unknown."

The researchers documented 10,799 incidents of skin cancer in 68,336 women in the Nurses' Health Study over 18 years of follow-up and examined the relationship between rotating night shifts and skin cancer. They found that higher duration of working rotating nightshifts was associated with a significantly lower risk of skin cancer.

When examining the effect of night shift work on different types of skin cancer, although the risk for each skin cancer (basal cell carcinoma, squamous cell carcinoma, and melanoma) decreased, the strongest association was observed for melanoma. Working ten or more years of rotating night-shifts was associated with 44 percent decreased risk of melanoma.

The researchers also found that darker-haired women in the study had the lowest risk of skin cancer. There were no differences in risk by sunlight exposure level at baseline, geographic residence or body location of skin cancer. That the inverse association was strongest among women with dark hair raises the possibility for several mechanistic explanations, including a genetic component that may affect both the extent of melatonin suppression during night work and skin cancer risk.

"Although higher melatonin levels appear to be beneficial in individuals with stable circadian rhythms, in shift workers, for certain disease outcomes melatonin suppression may actually be more beneficial," concluded Dr. Schernhammer.


'/>"/>

Contact: Holly Brown-Ayers
hbrown-ayers@partners.org
617-534-1603
Brigham and Women's Hospital
Source:Eurekalert

Related biology news :

1. New study illustrates shifting biomes in Alaska
2. Vet meds big shift to more women, fewer men driven by falling barriers, more female grads
3. Shifting forms: Penn study shows how variations of same protein affect immune response
4. Epidemic played large role in shift of attitudes on abortion, author says
5. Bald eagle diet shift enhances conservation
6. Model predicts shifts in carbon absorption by forest canopies
7. Shifting cellular energy metabolism may help treat cardiovascular disease
8. Shape shifters: Researchers create new breed of antennas
9. Bacterial ropes tie down shifting Southwest
10. North Atlantic fish populations shifting as ocean temperatures warm
11. Changes in brain chemicals mark shifts in infant learning
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/1/2016)... Favorable Government Initiatives Coupled With ... Identification to Boost Global Biometrics System Market Through 2021  ... report, " Global Biometrics Market By Type, By ... 2011 - 2021", the global biometrics market is projected ... of growing security concerns across various end use sectors ...
(Date:5/16/2016)... 16, 2016   EyeLock LLC , a market ... opening of an IoT Center of Excellence in ... the development of embedded iris biometric applications. ... convenience and security with unmatched biometric accuracy, making it ... from DNA. EyeLock,s platform uses video technology to deliver ...
(Date:5/3/2016)...  Neurotechnology, a provider of high-precision biometric identification ... Identification System (ABIS) , a complete system for ... can process multiple complex biometric transactions with high ... face or iris biometrics. It leverages the core ... MegaMatcher Accelerator , which have been used in ...
Breaking Biology News(10 mins):
(Date:6/27/2016)...   Ginkgo Bioworks , a leading organism ... today awarded as one of the World Economic ... most innovative companies. Ginkgo Bioworks is engineering biology ... world in the nutrition, health and consumer goods ... customers including Fortune 500 companies to design microbes ...
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial ... Cary 5000 and the 6000i models are higher end machines that use the more ... the spectrophotometer’s light beam from the bottom of the cuvette holder. , FireflySci ...
(Date:6/23/2016)... ... 2016 , ... UAS LifeSciences, one of the leading manufacturers ... Probiotics, into Target stores nationwide. The company, which has been manufacturing high quality ... list of well-respected retailers. This list includes such fine stores as Whole Foods, ...
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
Breaking Biology Technology: