Navigation Links
Sheep's mucosa shows the way to more effective medicine for severe neurological diseases
Date:9/25/2013

improve access to the olfactory bulb.

"It's all done at nano-level, and the challenge is to find the vehicles that can transport the required medicine to the brain. In our attempts to come up with efficient vehicles we now point at some special liposomes and polymers that can bring an active substance to the olfactory bulb more than 2-3 times more efficiently than when using the standard techniques", explains di Cagno.

Liposomes are small spheres of fat, which is often used to protect active substance and carry them into the body. Polymers are long molecules that can be attached to the liposomes so that they can be made to look like water and thus not be rejected by the body's immune system.

The improved efficiency is very important for the development of future medicines for neurological diseases. Today a pill has to contain millions of times more active ingredients than the brain needs to fight the disease. But because the blood-brain barrier is so effective and the brain so good at throwing foreign substances out, you have to send an extreme amount of active substances towards the brain.

"In a pill patients receive extremely more medicine than they need, and when we talk about medicines with severe and unpleasant side effects, it is not good. It is therefore very important that we get better at delivering exactly the amount of active substances needed - and no more", says di Cagno.

The new liposomes and polymers from his and Barbara Luppi's work can not only carry the active ingredients efficiently through the slimy mucosa of a nose, so that they can reach the olfactory bulb. They can also do it over a longer time.

"We want to develop a vehicle that can release the active ingredients over a long time, over many hours, so the patients do not have to spray their nose too many times a day. In our experiments we still saw active substances being released after three hours, and we are very happy with that. One must
'/>"/>

Contact: Birgitte Svennevig
birs@sdu.dk
45-65-50-29-36
University of Southern Denmark
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. AcelRx Pharmaceuticals Receives First U.S. Patent for Small-Volume Oral Transmucosal Dosage Forms
2. New study shows how ICU ventilation may trigger mental decline
3. New research shows how heart cells communicate to regulate heart activity
4. Fossil record shows crustaceans vulnerable as modern coral reefs decline
5. New muscular dystrophy treatment shows promise in early study led by Childrens National
6. Novelty of eco-friendly bamboo garments lures consumers -- if the price is right, Baylor study shows
7. Red cedar tree study shows that Clean Air Act is reducing pollution, improving forests
8. Human brains are hardwired for empathy, friendship, study shows
9. Research on which gender pays for dates shows change and resistance from convention
10. UEA research shows moderate exercise could be good for your tendons
11. Southerners are less trusting, but trust is a factor in environmental cooperation, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2015)... CITY , June 25, 2015  Imagine a ... steps toward a healthier, happier life. That,s exactly what ... designed to do. The cutting-edge, portable health program provides ... real-life solutions to help improve your lifestyle and nutrition. ... awards dinner and gala Wednesday night, USANA,s THA was ...
(Date:6/24/2015)... Research and Markets( ... "Huawei Ascend Mate 7 Fingerprint Sensor - ... Huawei,s technological choice for the fingerprint ... Apple,s and Samsung,s one. The Ascend Mate 7 ... Cards, a main actor in capacitive sensing human ...
(Date:6/23/2015)... , June 23, 2015  Crossmatch™, a ... authentication solutions, today announced enhanced functionality of its ... solution.  The enhancements build on the native ... DigitalPersona Altus platform and provide expanded mobile ... In today,s environment of increasing cyber-attacks ...
Breaking Biology News(10 mins):@USANAinc's Personalized Nutrition Program Wins Industry Innovation Award 2Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2
... a mechanism that allows for asymmetrical cell division during ... mouse oocytes, the team discovered that chromosomes can recruit ... allows the oocyte to retain the majority of the ... while the other daughter cell (called a polar ...
... found only in the eye has given researchers at the ... to vision, is activated. The enzyme, phosphodiesterase 6 (PDE6), is ... into a cascade of signals to the brain. ... photoreceptors of the retina and has not been well-researched, in ...
... Replaces Passwords with Fingerprint ... Biometrics for Access to IT Systems, ... International, Inc. (OTC Bulletin Board: BKYI), a leader in,finger-based ... Sig-Tec, a leader in identity and access management,software solutions, ...
Cached Biology News:Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye 2Sig-Tec(R) and BIO-key(R) Deliver Advanced Biometric Security Solution to Ohio County Law Enforcement Agency 2Sig-Tec(R) and BIO-key(R) Deliver Advanced Biometric Security Solution to Ohio County Law Enforcement Agency 3Sig-Tec(R) and BIO-key(R) Deliver Advanced Biometric Security Solution to Ohio County Law Enforcement Agency 4
(Date:6/30/2015)... Kent, WA (PRWEB) , ... June 30, 2015 ... ... offers a hydrophilic filter that does not sacrifice selectivity to achieve faster flow ... construction combines extremely fine pores with significant open space to allow easy liquid ...
(Date:6/30/2015)... ... June 30, 2015 , ... The maximum number of ... currently outstanding common shares (including shares of unvested restricted stock). On June 29, 2015, ... sale price of Cryo-Cell’s shares reported on the OTCBB was $2.29 per share. , ...
(Date:6/30/2015)... DIEGO , June 30, 2015  The ... Education in Biosciences (CCE/Bio) and UC San Diego ... fermentation, to be held Aug.  12 – 14, ... ).  This three-day workshop provides an intense exposure ... industrial biotechnology, and is well-suited to biologists, process ...
(Date:6/30/2015)... June 30, 2015 /PRNewswire/ - RepliCel Life Sciences ... regenerative medicine company focused on the development of ... in its Phase 1/2 clinical trial of RCT-01, ... Achilles tendinosis, has been enrolled and their tissue ... injections. RCT-01 is comprised of non-bulbar dermal sheath ...
Breaking Biology Technology:New Nanofiber Membrane Provides Fast, Efficient Filtration 2Cryo-Cell Commences Tender Offer to Purchase its Common Stock, Up to 750,000 Shares at $3.25 per Share 2Cryo-Cell Commences Tender Offer to Purchase its Common Stock, Up to 750,000 Shares at $3.25 per Share 3UC San Diego Extension to Offer Third Annual Microbial Fermentation Workshop 2RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 2RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 3RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 4
... , SPRINGFIELD, Ill., Dec. 1 Prairie Heart ... was recently awarded two statuettes at the first-ever CLIO Healthcare ... CLIO Healthcare Awards recognizes creative excellence and innovation in the ... Awards, one of the world,s most recognized awards competitions for ...
... ... to small and medium sized health care providers without breaking the bank. , ... (PRWEB) December 1, 2009 -- PacsDrive, LLC. ... new DICOM compatible cloud storage service. The PacsDrive service enables small and medium sized health ...
... ... to Synergy Business Solutions to maintain quality service. , ... Seattle, WA (PRWEB) December 1, 2009 -- Synergy ... Software, a Bellevue, WA business technology provider. The move was necessary due to a ...
Cached Biology Technology:Prairie Heart Institute of Illinois Wins Two CLIO Healthcare Awards 2PacsDrive Announces Low Cost Medical Imaging Storage Service, Seeks to Alter Status Quo in Health Care IT 2Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 2Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 3
... use in the Microsart e.motion are sterile-sealed, without ... a specially designed individual package on a band. ... of membrane filter units ensures that they are ... sealed band guarantees uniform dispensing of the individual ...
...
...
These 22x40mm rectangular No.1 Corning cover glasses are made from No. 0211 zinc titania glass and are 0.16 to 0.19mm thick. • Approx. Pcs Oz : 73...
Biology Products: