Navigation Links
Shedding light on the 'dark matter' of the genome
Date:11/29/2011

ow it came into existence."

The comparison of the genes and their introns revealed a unique example that may shed some light on these evolutionary processes: compared with its sister species, one of the studied genes of M. graminicola acquired an intron only recently and this intron then rapidly increased in frequency to near fixation. Why a new intron could so rapidly become fixed in this gene in M. graminicola is a mystery. "Maybe individuals carrying this intron have a fitness advantage compared to individuals without the intron," Croll muses, "this is our first evidence that natural selection may play a role in intron fixation".

Effects on fitness remain unclear

Researcher can still only speculate whether introns offer any general advantages to eukaryotes. Many more experiments will be needed to confirm or discard current ideas regarding the role of introns in genome evolution. "For example, do introns affect the fitness of a species, does the loss or gain of an intron increase fitness, decrease fitness or have neutral consequences for an individual or a species? We simply do not know", says the ETH professor.

As a result of their comparison across several fungal genomes and individual genes, the ETH Zurich researchers also found the first concrete examples illustrating that introns can multiply and insert themselves elsewhere in the genome. The researchers were able to identify whole families of closely related introns, and then determine the frequency with which a particular intron family was present in the genome.

Analysing human introns next?

The researchers are convinced that their work will lead to a better understanding of intron evolution for all eukaryotes. Following their example, one can perform similar gene or genome analysis in other organisms, especially due to the rapid development of ever faster and cheaper sequencing technologies. Fungi have relatively small genome
'/>"/>

Contact: Bruce McDonald
bruce.mcdonald@agrl.ethz.ch
41-446-323-847
ETH Zurich/Swiss Federal Institute of Technology
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Foot and mouth disease may spread through shedding skin cells
2. Shedding light on cancer cells
3. New research aims to shed light on how aging affects immunity
4. Smithsonian scientists use fossil feathers reveal lineage of extinct, flightless ibis
5. Genome sequence sheds new light on how plants evolved nitrogen-fixing symbioses
6. Brain, repair thyself: Studies highlight brains resiliency to damage
7. Trees adapt to poor levels of sunlight to effectively process carbon, study shows
8. Wildlife Conservation Society helps scarlet macaws take flight in Guatemala
9. Ecological light scattering film for brand protection, packages and consumer products
10. Mid-ocean creatures control light to avoid becoming snacks
11. ORNL fundamental discovery casts enzymes in new light
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/9/2015)... SAN JOSE, Calif. , April 9, 2015 /PRNewswire/ ... of human interface solutions, announced today that it will ... 2015 on Thursday, April 23, 2015, after the close ... call for analysts and investors at 2:00 p.m. PT ... information.    To participate on the live ...
(Date:4/2/2015)... Germany , April 2, 2015 ... fingerprint tests DERMALOG by far outperforms the strongest ... always maintaining high accuracy, the system is capable ... Hence, the speed proves up to be ten ... faster than its runner-up performance.      ...
(Date:4/2/2015)... Fingerprint Cards (FPC) has received ... the distributor World Peace Industrial Group (WPI), part of ... the major part of the shipments will take place ... smartphone manufacturers in China . The ... communicated revenue guidance of + 1 000 MSEK for 2015.  ...
Breaking Biology News(10 mins):Synaptics to Report Third Quarter Results on April 23 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2
... 26, 2011Magnetic resonance tractography (MRT) is a valuable, ... and, as MRT methods and technologies advance, has ... on brain activity and connectivity. Critical information about ... explored in a forward-looking review article in the ...
... Texas at Austin researchers have discovered how to extract and ... objects are from the focus distance, a feat only accomplished ... Like a camera, the human eye has an auto-focusing system, ... humans do not require trial and error to focus an ...
... used local anesthetic, may more easily wiggle into a ... compounds that carry a negative charge, a new study ... more complete understanding of the molecular-level mechanisms behind pain-blocking ... use. Most scientists believe that local anesthetics prevent ...
Cached Biology News:Researchers develop optimal algorithm for determining focus error in eyes and cameras 2
(Date:4/29/2015)... 29, 2015 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" or "the Company") today ... 2014. Biorem,s complete fiscal 2014 year-end financial statements and MD&A have been ... , 2013 , 2014 , 2013 Revenue ... 19,596 Gross profit 1,326 , 1,703 , 2,231 ... 1,493 , 3,377 , 4,562 Ebitda* 92 ...
(Date:4/29/2015)... 2015 Cambrex Corporation (NYSE: CBM ) announced ... Friday, May 1, 2015 before the market opens. , ... host a conference call to discuss the financial results. First ... , Friday, May 1, 2015 at 8:30 a.m. Eastern ... U.S.1-719-325-2454 for International  Passcode:  7993632 Dial-in Replay: ...
(Date:4/29/2015)... The leading Regenerative Veterinary Medicine Company, VetStem ... cell therapy has processed more than 11,000 samples. ... successful treatment for horses with potentially fatal injuries to ... worldwide exclusive license for adipose-derived (fat derived) stem cell ... treated in January 2004. Shortly after, the first dogs ...
(Date:4/29/2015)... - Northern Biologics Inc., a privately held biotechnology company ... strategic collaboration with Celgene Corporation.  As part of ... upfront cash payment. It will use the funds ... will have the right to receive additional future ... Under the agreement, Northern Biologics ...
Breaking Biology Technology:Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 2Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 3Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 4VetStem Biopharma -Regenerative Cell Therapy has processed over 11,000 samples 2Northern Biologics and Celgene Enter Strategic Collaboration 2
... predicting and quashing environmental decoherence, a phenomenon that has proven ... the way of quantum computing. The findings based ... and confirmed by experiments at the University of California Santa ... of the journal Nature . Quantum mechanics states ...
... July 20, 2011 Regulus Therapeutics Inc ., ... innovative medicines targeting microRNAs, today announced that it has ... GlaxoSmithKline (GSK), triggering a preclinical milestone payment from GSK. ... its microRNA alliance with GSK, which is focused on ...
... July 20, 2011 ReSearch Pharmaceutical Services, Inc. ... global Phase II-IV clinical development solutions to the ... following key additions to its Operational and Senior ... Davis, II, as Chief Information Officer and Executive ...
Cached Biology Technology:Discovery may overcome obstacle for quantum computing 2Regulus Therapeutics and GlaxoSmithKline Name a Third Alliance microRNA Target Triggering a Preclinical Milestone Payment 2Regulus Therapeutics and GlaxoSmithKline Name a Third Alliance microRNA Target Triggering a Preclinical Milestone Payment 3Regulus Therapeutics and GlaxoSmithKline Name a Third Alliance microRNA Target Triggering a Preclinical Milestone Payment 4RPS Continues Expansion of Global Clinical, Regulatory, Medical, and Operational Leadership 2RPS Continues Expansion of Global Clinical, Regulatory, Medical, and Operational Leadership 3
L1 Protein of Human Papilloma Virus Purified Anti-Viral-transformed cells clone CAMVIR-1, Isotype Mouse IgG 2a , 0.1 mg Consult technical datasheet for details....
ANTI 5-HYDROXYTRYPTOPHAN CONJ....
PAb to Hu-IFN-Alpha/Beta R2 [(IFNAR2) CD118], Rabbit Serum, neutralizing Binds to but does not neutralize human interferon alpha/beta receptor...
IMAGEQUANT 100 IQTL, 1 EA. Category: ImageQuant CCD Imagers....
Biology Products: