Navigation Links
Shared survival mechanism explains why 'good' nerve cells last and 'bad' cancer cells flourish
Date:12/15/2008

Specifically, according to the study, cytochrome c's ability to induce death can be turned off if the cellular environment contains high levels of antioxidants. Healthy neurons and cancer cells have increased levels of the antioxidant glutathione (GSH), which is generated by glucose metabolism through the pentose phosphate pathway. Thus, both neurons and cancer cells are able to resist cell death in part via their reliance on glucose metabolism.

"For neurons and cancer cells, evolution has come up with ways to restrict the cell death pathway. Our results provide insight into the mechanism behind this adaptive advantage," Deshmukh said. "They also bring together the fields of cancer and neurobiology and suggest that the mechanisms used by neurons to evade cell death could be the same ones adapted by dividing cells during their progression toward cancer."

The UNC scientist said his lab's further systematic explorations for other similarities between these cell types may offer insights into turning the cell death process back on in cancer cells.


'/>"/>

Contact: Les Lang
llang@med.unc.edu
919-966-9366
University of North Carolina School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. UI and ISU establish shared DNA sequencing instrumentation
2. Salmon smolt survival similar in Columbia and Fraser rivers
3. Research challenges conventional notions about salmon survival
4. Similar survival rates for Pacific salmon in Fraser, Columbia Rivers raises new questions
5. U of MN study shows link between gene variations and cancer survival
6. Second lumpectomy for breast cancer reduces survival rates
7. The IMF says journal editorial documents dramatic increase in survival since the 1980s
8. International team reveals first prognosticator of survival in aggressive cancer
9. The MDS Foundation supports the FDAs decision to expand vidaza label to include survival data
10. Monash researchers uncover cancer survival secrets
11. Scientists find elephant memories may hold key to survival
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... According to a new market research report ... Control, Intrusion Detection, Parking Management, Under Vehicle Inspection), End ... - Global Forecasts to 2020", published by MarketsandMarkets, The ... $25 Billion in 2014 and is expected to reach ... 8.69%. Browse 116 market data Tables and ...
(Date:11/21/2014)... SAN JOSE, Calif. , Nov. 20, 2014 /PRNewswire/ ... a global leader in microcontroller (MCU) and touch technology ... digital temperature sensors with the widest V ... family delivers higher temperature accuracy and faster I 2 ... nonvolatile registers and serial EEPROM memory making them ideal ...
(Date:11/18/2014)... NEW YORK , Nov. 18, 2014 /PRNewswire/ ... iris-based identity authentication solutions, and MorphoTrust USA ... solutions and services, today announced a strategic partnership ... across enterprise, motor vehicle administration (MVA), airport screening ... leader in identity-related solutions, MorphoTrust serves consumers through ...
Breaking Biology News(10 mins):Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 3
... Institute of Harvard and MIT today announced that they ... grant from the National Institutes of Health (NIH) to ... which can probe the proteins, signaling pathways and cellular ... The Broad Institute is among nine institutions to receive ...
... in the USA have established a way to predict ... finding could provide a model to predict and potentially ... is a serious, ancient water-borne infectious disease, which is ... bacterium that causes cholera, Vibrio cholerae, has ...
... eight percent of America,s population, diabetes can lead to blindness, ... University researchers, a new cure based on advances in ... Shimon Efrat from TAU,s Sackler Faculty of Medicine, whose research ... developed a way to cultivate cells derived from insulin-producing beta ...
Cached Biology News:Broad Institute awarded grant to develop chemical probes for human biology and disease 2Broad Institute awarded grant to develop chemical probes for human biology and disease 3Battling diabetes with beta cells 2
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... that have vanished all through the industrial areas of ... errand. Instead, efforts are underway to develop a new ... out of Wisconsin's institutes of higher education and private ... with the intent of assisting these technol with high ...
... , a provider of health-care and business technology, announced a ... new Medicaid Management Information System (MMIS). The new system is ... announced in November, contracts EDS to implement its InterChange health ... Health and Family Services . The contract is worth approximately ...
... Johnson Controls Inc. has completed the sale ... company, Valeo. Valeo is based in Paris and ... the business, headquartered in Pontoise, France, which manufactures ... Controls bought the division from another French technology ...
Cached Biology Technology:Will tech transfer save Wisconsin's economy? 2Will tech transfer save Wisconsin's economy? 3Will tech transfer save Wisconsin's economy? 4Will tech transfer save Wisconsin's economy? 5Will tech transfer save Wisconsin's economy? 6Will tech transfer save Wisconsin's economy? 7Will tech transfer save Wisconsin's economy? 8State picks long-time vendor for $189m Medicaid information system 2
Donor feline serum and plasma...
Complete cell culture media with cytokines...
NPT1 (M-19)...
... cups provide flexible sealing lips for ... surfaces. ,PFG: Flat cup ,PBG: Bellows ... Multiple Bellows cup , Range ... 200 mm , Multiple suction cup ...
Biology Products: