Navigation Links
Shades of 1918? New study compares avian flu with a notorious killer from the past
Date:2/10/2009

In the waning months of the First World War, a lethal virus known as the Spanish flu (influenza A, subtype H1N1), swept the United States, Europe and Asia in three convulsive waves. The year was 1918. The ensuing pandemic claimed up to 100 million victims, most of whom succumbed to severe respiratory complications associated with rapidly progressing pneumonia. Many died within days of the first symptoms.

In a new study, Carole Baskin, formerly assistant research professor at Arizona's Biodesign Institute, currently with Science Foundation Arizona, and an interdisciplinary team of collaborators, compared the recent avian strain known in the scientific community as H5N1, with genetic ressortants of the 1918 virussource of the most severe influenza pandemic in recorded history. The results, which appear in the latest issue of the Proceedings of the National Academy of Science, are sobering. H5N1 was found to replicate profusely within the first 24 hours, causing severe damage to respiratory tissues while sending the host's innate immune response into a lethal overdrive, reminiscent of the trajectory of the original 1918 virus.

The threat of an avian flu pandemic hasn't gone away and emergency preparedness efforts may be inadequate to deal with the scope of such a pandemic, were one to occur. "In order to come up with vaccines and therapies, you have to understand the disease," Baskin stresses. "That's why I think this type of pathogenesis study is so important."

Although H5N1 is not readily communicable between humans, it has nevertheless killed over 400 people to date as a result of human-avian interactions, primarily in Vietnam, Thailand, China, Egypt and Indonesia, according to the World Health Organization. The mortality rate for those stricken with highly pathogenic avian influenza (HPAI) H5N1 is 63 percent. Should a series of modifications allow the virus to pass from person to person, the consequences for humankind
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4 5

Related biology news :

1. International study identifies gene variants associated with early heart attack
2. Genetic study shows direct link between vitamin D and MS susceptibility gene
3. Statement by the Egg Nutrition Center and American Egg Board on Diabetes Care study on egg consumption
4. Molecule that suppresses immune response under study in type 1 diabetes
5. UNC study: Tinkering with the circadian clock can suppress cancer growth
6. Small male chimps use politics, rather than aggression, to lead the pack, U of Minnesota study says
7. Results of the third school nutrition dietary assessment study published
8. TGen Clinical Research Services at Scottsdale Healthcare and Mayo Clinic study new cancer drug
9. Study finds rescue course of antenatal steroids improves outcome in premature babies
10. Brain structure assists in immune response, according to Penn vet study
11. Study finds MRSA in Midwestern swine, workers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Shades of 1918? New study compares avian flu with a notorious killer from the past
(Date:11/10/2014)... shelves in early 2010, and people have used them ... be tossed into a washing machine without ever having ... though, has come with risks for young children. , ... found that from 2012 through 2013, U.S. poison control ... years of age swallowing, inhaling, or otherwise being exposed ...
(Date:11/7/2014)... November 6, 2014 Leading Biometric companies ... mobile security revolutionizing online transactions.  Companies in focus today are: ... (NYSE: BABA ), Google Inc. (NASDAQ: ... Inc. (NASDAQ: EBAY ) and MasterCard Inc. (NYSE: ... and NXTDW), a biometric authentication company focused on the growing ...
(Date:11/6/2014)... PITTSBURGH--Speed is an asset for a predator. Except when that ... The tiger beetle, relative to its size, is the fastest ... 120 body lengths per second (at about five miles per ... To take the sprinting gold from the tiger beetle, a ... BUT! The tiger beetle has a problem. At peak speeds, ...
Breaking Biology News(10 mins):Study finds laundry detergent pods, serious poisoning risk for children 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6The tiger beetle: Too fast to see 2
... spent at sea, a magnetic map is apparently responsible for ... of data collected over 56 years and reported online on ... publication. "To find their way back home across thousands ... that exists where they first enter the sea as juveniles," ...
... When migrating, sockeye salmon typically swim up to 4,000 miles into ... reaches of the rivers in which they were born to spawn ... wondered how salmon find their way to their home rivers over ... A new study, published in this week,s issue of ...
... $25 billion in health information technology (IT) as a ... little is known about how IT applications improve patient ... Missouri nursing informatics expert suggests that sophisticated IT leads ... staff, which allows staff to more efficiently coordinate care ...
Cached Biology News:Magnetic map guides salmon home 2Animal magnetism: First evidence that magnetism helps salmon find home 2Animal magnetism: First evidence that magnetism helps salmon find home 3Information Technology improves patient care and increases privacy, MU informatics expert says 2
(Date:11/22/2014)... 2014 During his lifetime Richard L. ... to surround himself with great people and take risks ... friends often marveled at his extraordinarily courageous attitude when ... and -- even with his death impending—that’s how he ... that would ultimately take his life. , Carrying on ...
(Date:11/22/2014)... 22, 2014 The “Chiral Chromatography ... by Material (Metal, Glass, Plastic), by Application [GC, ... - Forecast to 2018” analyses and studies the ... North America, Europe, Asia, and Rest of the ... 15 figures spread through 135 pages and in-depth ...
(Date:11/21/2014)... --  TRU-D SmartUVC LLC and its UK partners, Rapid ... robot, TRU-D SmartUVC, at FIS 2014 in Harrogate, ... at Stand 23. The conference, hosted by Federation ... largest infection-related event of its kind and brings together ... leading events of its type throughout the world. This annual ...
(Date:11/21/2014)... (PRWEB) November 20, 2014 ... (XNA, Chassis, Oligos, Enzymes, Cloning kits), Technology ... Application (Biofuels, Pharmaceuticals, Biomaterials, Bioremediation) - Global ... major market drivers, threats, opportunities, and challenges. ... 46 figures spread through 185 pages and ...
Breaking Biology Technology:Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 4Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 5TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 2TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 2Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 4
... Prairie-,based molecular diagnostics service and technology company, announced today,that ... and Elizabeth A. Skinner,as VP - Legal, Quality and ... Watts Golf, and has previously,served as VP of Finance ... and corporate controller of NCR Corporation. He holds a ...
... Greater Metropolitan NYC and Long Island, JACKSONVILLE, ... (OTC: PHLC) (the "Company") announced today that it ... East Coast in,November. AQUISS(TM) initially will be ... including Manhattan, Brooklyn, Queens, the Bronx, and,Long Island. ...
... Bioscience, Inc.,today announced the receipt of a $2.4 ... Institute to support the project entitled "Development,of Oncomine ... (Logo: http://www.newscom.com/cgi-bin/prnh/20070213/NYTU093LOGO ) Compendia ... the principal,investigator for this project, will assume a ...
Cached Biology Technology:Access Genetics Announces New Executive Appointments 2Phlo Affiliate to Launch AQUISS(TM) on East Coast 2Compendia Bioscience Announces the Receipt of a $2.4M SBIR Award and Related Management Changes 2
... Round Well Plate Sterile ... wide range of 384-well ... high-throughput screening and research. ... assays and are suitable ...
Request Info...
Aldolase A (N-15)...
Bovine Aortic Smooth Muscle Cells (BAOSMC) (>500,000 cells)...
Biology Products: