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Severely restricted diet linked to physical fitness into old age
Date:10/24/2007

calorie diet had significantly higher physical performance scores than animals fed a normal diet. They also had less fat, a lower fat-to-lean ratio, and lower adipose tissue secretion of IL-6 and circulating levels of C-reactive protein.

The stumbling block on this path to remaining forever young is that humans could not adhere to such a severe diet.

Based on an average of 2,000 calories per day for adult women and 2,500 for men, cutting by 40 percent would mean surviving on 1,200 and 1,500 calories per day, respectively, said You.

Its very difficult for people to maintain that type of diet for short periods of time, and it would be nearly impossible over a lifetime, while staying healthy. Starting on a diet like that in the senior years would be harmful.

You said that a more moderate form of caloric restriction, 8 percent, is achievable in humans, based on recent findings, and may have positive effects on specific oxidative stress and inflammatory biomarkers.

Preclinical testing of this 8-percent regimen could be informative and beneficial in translating to humans, he said.


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Contact: Lois Baker
ljbaker@buffalo.edu
716-645-5000 x1417
University at Buffalo
Source:Eurekalert

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