Navigation Links
Several common differentially expressed genes between Kashin-Beck disease and Keshan disease
Date:9/14/2013

Kashin-Beck disease (KBD) and Keshan disease (KD) are major endemic diseases in China. Postgraduate Xi Wang et al., under the guidance of Professor Xiong Guo from the Institute of Endemic Diseases of the Faculty of Public Health, Medicine College of Xi'an Jiaotong University, Key Laboratory of Environment and Gene Related Diseases in Ministry of Education, Key Laboratory of Trace Elements and Endemic Diseases of Health Ministry, set out to tackle these two endemic diseases. After several years of innovative research, they have made significant progress in determining the etiology and pathogenesis of these diseases at a molecular level; in particular, the identification of some common differentially expressed genes. Their work, titled "Comparing gene expression profiles of Kashin-Beck and Keshan diseases occurring within the same endemic areas of China", was published in SCIENCE CHINA Life Sciences. 2013 Vol.56(9).

KBD and KD are distributed from the northeast to the southwest of China, where the selenium content is low in the soil. In China, there are 660000 KBD and 40000 KD patients, and approximately 30 million people are at risk. KBD is an endemic osteoarthropathy, the pathologic changes of KBD included significant alterations in chondrocyte phenotype, necrosis, and apoptosis, and abnormal terminal chondrocyte differentiation. The mainly pathologic changes of KD are multifocal myocardial necrosis and fibrosis that can result in cardiogenic shock and congestive heart failure. KD is an endemic myocardosis that happened in women and preschoolers. Since osteoarthritis and myocardium deformities, the most of KBD and KD patients will partially or completely lose their abilities to work even self-care, which seriously reduces their quality of life, and also bring heavy medical burden to society; the etiology and pathogenesis of KBD and KD remain unclear. However, both diseases happened in the same area of China. Moreover, the living conditions of KBD and
'/>"/>

Contact: GUO Xiong
guox@mail.xjtu.edu.cn
Science China Press
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Antiviral enzyme contributes to several forms of cancer, University of Minnesota researchers say
2. Birds evolved ultraviolet vision several times
3. Single protein targeted as the root biological cause of several childhood psychiatric disorders
4. NASA satellite sees several western US fires blazing
5. UCLA researchers invent portable device for common kidney tests
6. Trust in leaders, sense of belonging stir people to safeguard common goods, analysis shows
7. Common autism supplement affects endocrine system
8. Metastatic pancreatic, primary breast cancer have common growth mechanisms, study suggests
9. MacaInfo.org Offers In-Depth Answers the 20 Most Common Questions People Have about Maca
10. Toward broad-spectrum antiviral drugs for common cold and other infections
11. Complex genetic architectures: Some common symptoms of trisomy 21
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... , October 16, 2014 NXT-ID, Inc. ... the "Company"), a biometric authentication company focused on the ... leading edge technologies including Wocket™, the Smart Wallet, at ... Conferenece. FiRe is a leading global conference on the ... Hosted by Mark Anderson , founder and publisher ...
(Date:10/15/2014)... pandemic risk from strains of influenza virus increases with ... to become complacent that the most substantial threats have ... Influenza pandemics arise when a new virus strain – ... – spreads in the human population. There have been ... worst of which – the 1918 Spanish Flu – ...
(Date:10/15/2014)... admitted Johannes Gutenberg University Mainz (JGU) as a ... continues to maintain a significant nationwide standing in ... acceptance of Johannes Gutenberg University Mainz as a ... in the national and international competition for the ... Rhineland-Palatinate can be proud that Mainz University has ...
Breaking Biology News(10 mins):NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 3
... rare frog (Amolops tormotus) in China sings like a ... sounds. Now scientists say that these concave-eared torrent frogs ... findings, to appear in the March 16 issue of ... being able to communicate like bats, whales and dolphins, ...
... at Austin have developed a quick and simple way to ... role in infection and immunity. , The sugars coating bacteria ... cloaking the bacteria from the immune system of their host. ... catch these rapid changes. , "There's a growing ...
... the Forsyth Institute have discovered a new mechanism responsible ... locate themselves on the left or right side of ... mechanism, garnered through the study of three different vertebrates ... a single common mechanism has been identified in left-right ...
Cached Biology News:Rare Chinese frogs communicate by means of ultrasonic sound 2Rare Chinese frogs communicate by means of ultrasonic sound 3Scientists seek to unwrap the sweet mystery of the sugar coat on bacteria 2Forsyth scientists gain greater understanding of how embryos differentiate left from right 2Forsyth scientists gain greater understanding of how embryos differentiate left from right 3
(Date:10/19/2014)... 19, 2014 The report "Unmanned ... Homeland Security), Technology, Payload, Type & by Geography ... the global unmanned ground vehicle market into various ... of market sizes. The report also identifies the ... impacting it along with the adoption trends. , ...
(Date:10/18/2014)... The Asian arthroscopic devices report defines and segments the ... revenue. The arthroscopic devices market in Asia is estimated ... CAGR of 6.5% from 2013 to 2018. , Browse ... to get an idea of the in-depth analysis provided. ... arthroscopic devices market in the same region, and is ...
(Date:10/18/2014)... 2014 According to a new market ... Type - Global Trends & Forecasts up till 2017”, ... in 2011. This value is expected to increase from ... with 10% CAGR during the same period. North America ... market in terms of hydraulic horse power supplied by ...
(Date:10/17/2014)... Germany , October 17, 2014 /PRNewswire/ ... research in cancer and other diseases will benefit ... Society of Human Genetics annual meeting   ... Ingenuity ®  Knowledge Base greatly exceeds any comparable ... Ingenuity ®  Variant Analysis™ adds fully integrated BIOBASE ...
Breaking Biology Technology:Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 2Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 3Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6
... , CAMBRIDGE, Mass., July 14 Idenix Pharmaceuticals, ... report its financial results for the second quarter of 2009 on ... , In conjunction with the issuance of ... 4:30 p.m. ET on Monday, July 20, 2009 to discuss the ...
... , , , LAKE ... technology company focused on improving blood collection, separation, safety and ... agreement with Verax Biomedical Incorporated to market, sell and distribute ... used to detect bacterial contaminants in donated blood platelets. ...
... , VIENNA, Austria, July 14 Elan ... WYE ) presented information this week at the Alzheimer Association ... and one podium presentation about the growing burden of care and ... This information sheds light on the impact of AD, which, ...
Cached Biology Technology:Improving Transfusion Safety: Fenwal, Verax Biomedical Sign Agreement for Rapid, Point-of-Care Bacteria Test 2Improving Transfusion Safety: Fenwal, Verax Biomedical Sign Agreement for Rapid, Point-of-Care Bacteria Test 3Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease 2Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease 3Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease 4Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease 5Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease 6Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease 7
Recombinant Mouse Noggin...
... Kit Kit Includes: Histone Deacetylase ... Histone Deacetylase 3 (HDAC3) Antibody, Catalog #2632, ... Catalog #2072, 40 ul Histone Deacetylase 5 ... Deacetylase 6 (HDAC6) Antibody, Catalog #2162, 40 ...
An instrument that delivers an accurate and uniform amount of light energy to cells to photoactivate csiRNA products....
... seals labware. Waterproof, moisture-proof film prevents ... Can be folded repeatedly and twisted ... lengthwise at 21C (70F), wrapping film ... is removed, film only partially returns ...
Biology Products: