Navigation Links
Serotonin plays role in many autism cases, studies confirm
Date:2/24/2011

SAN ANTONIO (Feb. 24, 2011) Mouse models are yielding important clues about the nature of autism spectrum disorders, which impact an estimated one in 110 children in the U.S.[1] In labs at the UT Health Science Center San Antonio, researchers are studying strains of mice that inherently mimic the repetitive and socially impaired behaviors present in these disorders.

Georgianna Gould, Ph.D., research assistant professor of physiology in the Graduate School of Biomedical Sciences, is eyeing the role that serotonin plays in autism spectrum disorders.

Serotonin is known for giving a sense of well-being and happiness. It is a neurotransmitter, a chemical that acts like a radio tower in the brain conveying signals among cells called neurons. Thirty percent of autism cases may have a serotonin component.[2]

In a recent paper in the Journal of Neurochemistry, Dr. Gould and colleagues showed that a medication called buspirone improved the social behaviors of mice. Buspirone is approved by the U.S. Food and Drug Administration for use in adults as an anti-anxiety and antidepressant adjuvant medication.

Some genetic variations result in diminished transmission of serotonin between neurons. Buspirone increased transmission by partially mimicking the effects of serotonin at cellular sites called receptors.

Reactions to newly encountered mouse

Social interaction behaviors of the mice were measured by placing them in a three-chamber social interaction test and positioning a "stranger" mouse in one of the chambers. Buspirone-treated mice spent more time in the chamber with the stranger mouse than untreated mice and more time sniffing the stranger.

"No animal model is completely characteristic of humans, and we're far from saying that buspirone is a treatment for behaviors of autistic people," Dr. Gould said. "But this does offer further proof that serotonin is involved in a significant proporti
'/>"/>

Contact: Will Sansom
sansom@uthscsa.edu
210-567-2579
University of Texas Health Science Center at San Antonio
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Gestational diabetes linked to serotonin and dietary protein
2. Inhibiting serotonin in gut could cure osteoporosis
3. Lack of happiness hormone serotonin in the brain causes impaired maternal behavior in mice
4. Researchers iron out new role for serotonin
5. Measles virus plays role in Pagets disease of bone, Pitt-led team says
6. Natural dissolved organic matter plays dual role in cycling of mercury
7. Allô allô! Moms voice plays special role in activating newborns brain
8. New type of liquid crystal promises to improve performance of digital displays
9. Academys mollusk collection plays key role in Gulf oil impact study
10. Study finds protein that plays key role in early embryonic development
11. McGill plays important role in new global cancer-research network
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Serotonin plays role in many autism cases, studies confirm
(Date:4/1/2015)... 1, 2015   Medisafe ™, the leading global ... iOS and Android smartphones and ... into the platform to allow patients to track and ... first time, patients will be able to visualize in ... important biometrics, such as glucose levels and blood pressure. ...
(Date:3/24/2015)... Mar. 24, 2015 Research and Markets ... "Global Iris Recognition Market 2015-2019" report to ... Iris Recognition market to grow at a CAGR of ... report covers the present scenario and the growth prospects ... 2015-2019. To calculate the market size, the report considers ...
(Date:3/23/2015)... --  HOYOS Labs , a leading global authentication infrastructure ... Company will demonstrate multiple biometrics-based technologies under its identity ... on March 23 through 25, 2015, in ... IEEE Biometric Open Protocol Standard; free biometrics-based consumer app, ... system. BOPS was invented by HOYOS Labs and contributed ...
Breaking Biology News(10 mins):Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3
... public health threats from infectious diseases in hurricane-devastated areas ... infections rather than exotic diseases. These common infections can ... little common sense. , "Deadly diseases, such as typhoid ... and floods in areas where these diseases do not ...
... that once characterized expansive tracts of tropical rainforest gets ... how big a role these winged gardeners play is ... Chicago and several Latin American universities are about to ... in Mexico's gulf coast state of Veracruz. , Henry ...
... details of a family of mysterious objects called microcompartments ... bacteria. The discovery was published Aug. 5 in the ... how microcompartments are built, and what the pieces look ... and biochemistry, and a member of the UCLA-DOE Institute ...
Cached Biology News:Hurricane aftermath: Infectious disease threats from common, not exotic, diseases 2Birds and bats sow tropical seeds 2Birds and bats sow tropical seeds 3Field tested: Grasslands won't help buffer climate change as carbon dioxide levels rise 2Field tested: Grasslands won't help buffer climate change as carbon dioxide levels rise 3
(Date:5/5/2015)... 2015  Indianapolis-based medical device manufacturer NICO Corporation ... of products including the BrainPath® and Myriad™ technologies ... brain abnormalities and then removing affected tissue. More ... than 50 institutions throughout the United ... included in 12 abstracts, three peer-reviewed publications, and ...
(Date:5/4/2015)... NEW YORK , May 4, 2015 /PRNewswire-USNewswire/ ... system for granted. But for certain infants with ... and death are stark consequences of their impaired ... Langone Medical Center have identified an important role ... infection resulting from Mycobacterium tuberculosis, the bacterium causing ...
(Date:5/4/2015)... , May 4, 2015   St. ... a significantly better computer tool for finding genetic ... cancers but were difficult to identify with whole-genome ... journal Nature Methods . The ... Copy Number Segmentation by Regression Tree in Next ...
(Date:5/4/2015)... BROOK, N.Y. , May 4, 2015 /PRNewswire/ ... a $250,000 cooperative research and development agreement (CRADA) ... to advance the development of TRB-N0224 for the ... animals, including dogs and cats.  Traverse Biosciences has ... TRB-N0224 for the treatment and control of periodontal ...
Breaking Biology Technology:NICO Corporation Gains Market Expansion after Multiple Published Clinical Articles Support Access Technology for Deep Brain Lesions 2NICO Corporation Gains Market Expansion after Multiple Published Clinical Articles Support Access Technology for Deep Brain Lesions 3Researchers Discover A Novel And Unexpected Role For Calcium In Controlling Inflammation During Chronic Lung Infection 2Researchers Discover A Novel And Unexpected Role For Calcium In Controlling Inflammation During Chronic Lung Infection 3Scientists dramatically improve method for finding common genetic alterations in tumors 2Scientists dramatically improve method for finding common genetic alterations in tumors 3Scientists dramatically improve method for finding common genetic alterations in tumors 4Traverse Biosciences Executes Agreement with Aratana Therapeutics to Advance Development of TRB-N0224 for the Treatment and Control of Periodontal Disease in Pets 2Traverse Biosciences Executes Agreement with Aratana Therapeutics to Advance Development of TRB-N0224 for the Treatment and Control of Periodontal Disease in Pets 3Traverse Biosciences Executes Agreement with Aratana Therapeutics to Advance Development of TRB-N0224 for the Treatment and Control of Periodontal Disease in Pets 4
... SIAL ) will be presenting at the ... at 1:20 PM CT in Chicago., Interested ... the,Internet available at http://ir.sigmaaldrich.com . Users can ... the webcast on, http://ir.sigmaaldrich.com users will need ...
... Auditor at Annual Meeting, DEERFIELD, Ill., May 6 ... BAX ) today announced a quarterly,dividend and votes ... today., Baxter,s Board of Directors declared a quarterly ... payment represents a continuation of,the current rate. The quarterly ...
... Pharmaceuticals (Nasdaq:,SGXP) will announce financial results for the first ... will be followed by a live,conference call and webcast ... Grey, President and Chief Executive Officer, Stephen Burley, Chief,Scientific ... the,conference call to discuss financial results and business highlights., ...
Cached Biology Technology:SGX Pharmaceuticals Schedules Teleconference and Webcast to Discuss First Quarter 2008 Results and Provide Pipeline Update 2
Mouse monoclonal antibody raised against a partial recombinant WDR5. NCBI Entrez Gene ID = WDR5...
... Antibody against Nonmuscle Myosin II Heavy ... (Stored in TBS + 0.03% Thimerosal) ... peptide SDVNETQPPQSE corresponding to the C-terminus ... B (MHC-B) This antibody is effective ...
... Anti-Lipid Phosphate Phosphatase ... buffered aqueous solution ... buffered saline containing 0.08% ... derived from the human ...
... Synaptogyrin 2 ( Abpromise ... Antigen: Synthetic ... sequence amino acids 42-57 of ... Entrez Gene ID: ...
Biology Products: