Navigation Links
Sensor chip for monitoring tumors
Date:8/26/2011

This release is available in German.

A surgery is usually one of the first therapy options in cancer treatment. However, some tumors, such as brain tumors, can be difficult to operate on if there is a risk of damaging surrounding nerve tissue. Other cancerous tumors, such as prostate carcinoma, grow at a very slow rate and primarily affect older patients. Operating in these cases often lowers patients' quality of life without significantly extending their life expectancy.

A team of medical engineers headed by Prof. Bernhard Wolf at the TUM Heinz Nixdorf Chair of Medical Electronics have now developed a sensor chip that can be implanted close to a tumor. The sensor chip measures the concentration of dissolved oxygen in the tissue and wirelessly transmits this information to a receiver carried by the patient. The receiver forwards the data to the patient's doctor, who can then monitor the tumor's development and arrange for an operation or therapies such as chemotherapy. The tumor is thus continually monitored and the patient does not have to visit the practice or hospital as frequently for check-ups.

The sensor chip has already passed laboratory tests with cell and tissue cultures. The main challenge for the researchers was developing a sensor that functions entirely autonomously for long periods of time. The sensor must continue to function and deliver correct values even in the presence of protein contamination or cell debris. It also has to be "invisible" to the body so that it is not identified as a foreign object, attacked and encapsulated in tissue.

"We designed the sensor chip to self-calibrate to a set dissolved oxygen concentration at measurement intervals," explains engineer and project manager Sven Becker. "In addition, we enclosed the sensor chip, analysis electronics, transmitter and batteries in a biocompatible plastic housing."

Not even twice the size of a thumbnail, the sensor chip and electronics have a compact footprint. However, the package must be made even smaller before it can be implanted in cancer patients using minimally invasive surgery. In addition, the designers want to add additional sensors for measuring acidity and temperature. Also at the development phase is a miniature medication pump to be implanted with the sensor chip. The pump will be able to release chemotherapeutic agents in direct proximity to the tumor if necessary. Before moving on to the next phase, the sensor has to pass trials in animals. The researchers hope that the new technology will make cancer therapies more targeted and less aggressive for patients.


'/>"/>

Contact: Dr. Markus Bernards
bernards@zv.tum.de
49-892-892-2562
Technische Universitaet Muenchen
Source:Eurekalert

Related biology news :

1. New sensors streamline detection of estrogenic compounds
2. Penn molecular scientists develop color-changing stress sensor
3. New UC sensor promises rapid detection of dangerous heavy metal levels in humans
4. Navy, Marine Corps tests autonomous zero-power bathythermograph sensors
5. Nanowire-based sensors offer improved detection of volatile organic compounds
6. Development of a FRET sensor for real-time imaging of intracellular redox dynamics
7. UCLA scientists identify how major biological sensor in the body works
8. Quantum sensor tracked in human cells could aid drug discovery
9. For hearing parts of brain, deafness reorganizes sensory inputs, not behavioral function
10. New biosensor modelled on the immune system can detect, track and guide the clean-up of oil spills
11. New biosensor microchip could speed up drug development, Stanford researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/4/2017)... , April 4, 2017   EyeLock LLC , ... that the United States Patent and Trademark Office (USPTO) ... covers the linking of an iris image with a ... and represents the company,s 45 th issued patent. ... is very timely given the multi-modal biometric capabilities that ...
(Date:3/30/2017)...  On April 6-7, 2017, Sequencing.com will host the ... hackathon at Microsoft,s headquarters in Redmond, Washington ... developing health and wellness apps that provide a unique, ... is the first hackathon for personal genomics and ... in the genomics, tech and health industries are sending ...
(Date:3/30/2017)... YORK , March 30, 2017 Trends, ... type (physiological and behavioral), by technology (fingerprint, AFIS, iris ... voice recognition, and others), by end use industry (government ... and immigration, financial and banking, and others), and by ... Europe , Asia Pacific , ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... ... October 09, 2017 , ... ... the medical journal, Epilepsia, Brain Sentinel’s SPEAC® System which uses the surface ... detecting generalized tonic-clonic seizures (GTCS) using surface electromyography (sEMG). The prospective multicenter ...
(Date:10/7/2017)... ... October 06, 2017 , ... Phase ... metagenome deconvolution product, featuring the first commercially available Hi-C kit. Researchers can ... Hi-C metagenome deconvolution using their own facilities, supplementing the company’s full-service ProxiMeta ...
(Date:10/6/2017)... , ... October 06, 2017 , ... ... within the healthcare and technology sector at their fourth annual Conference where founders, ... 30 inspiring speakers and the ELEVATE pitch competition showcasing early stage digital health ...
(Date:10/5/2017)... ... 2017 , ... LabRoots , the leading provider of educational and interactive ... back to cancer research with a month-long promotion supporting the advancement of breast cancer ... can use promo code PinkRibbon to get 10 percent off their purchase of every ...
Breaking Biology Technology: