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Sensing the light, but not to see
Date:2/6/2013

uzzling question of why the light response of these amphioxus cells is several orders of magnitude higher than that of their more sophisticated, presumed descendents, the ipRGCs. (In mammals, the ipRGCs relay information on light and dark to the biological clock in the hypothalamus, where it is crucial for the regulation of circadian rhythms and associated control of hormonal secretion.)

By detailing how the large light response occurs in the amphioxus cells, Gomez and Nasi could relate their observations to the functional changes that may have occurred as the circadian receptors evolved and "eventually tailored their performance to the requirements of a reporter of day and night, rather than to a light sensor meant to mediate spatial vision." The light-sensing cells of amphioxus, they discovered, may be the "missing link" between the visual cells of invertebrates and the circadian receptors in our own eyes.


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Contact: Diana Kenney
dkenney@mbl.edu
508-289-7139
Marine Biological Laboratory
Source:Eurekalert  

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