Navigation Links
Selenium suppresses staph on implant material
Date:6/21/2012

PROVIDENCE, R.I. [Brown University] Selenium is an inexpensive element that naturally belongs in the body. It is also known to combat bacteria. Still, it had not been tried as an antibiotic coating on a medical device material. In a new study, Brown University engineers report that when they used selenium nanoparticles to coat polycarbonate, the material of catheters and endotracheal tubes, the results were significant reductions in cultured populations of Staphylococcus aureus bacteria, sometimes by as much as 90 percent.

"We want to keep the bacteria from generating a biofilm," said Thomas Webster, professor of engineering and orthopaedics, who studies how nanotechnology can improve medical implants. He is the senior author of the paper, published online this week in the Journal of Biomedical Materials Research A.

Biofilms are notoriously tough colonies of bacteria to treat because they are often able to resist antibiotic drugs.

"The longer we can delay or inhibit completely the formation of these colonies, the more likely your immune system will clear them," Webster said. "Putting selenium on there could buy more time to keep an endotracheal tube in a patient."

Meanwhile, Webster said, because selenium is actually a recommended nutrient, it should be harmless in the body at the concentrations found in the coatings. Also, it is much less expensive than silver, a less biocompatible material that is the current state of the art for antibacterial medical device coatings.

Webster has been investigating selenium nanoparticles for years, mostly for their possible anticancer effects. As he began to look at their antibiotic properties, he consulted with Hasbro Children's Hospital pediatrician Keiko Tarquinio, assistant professor of pediatrics, who has been eager to find ways to reduce biofilms on implants.

Studying selenium

For this study, Webster and first author Qi Wang grew
'/>"/>

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Selenium impacts honey bee behavior and survival
2. Transcatheter aortic valve implantation shows promise in patients with severe aortic stenosis
3. New materials could slash energy costs for CO2 capture
4. Computer model pinpoints prime materials for efficient carbon capture
5. KIT researchers succeed in realizing a new material class
6. NIST releases Gulf of Mexico crude oil reference material
7. Ozone treated water v. lethal microbial material
8. Diabetes Research Institute develops oxygen-generating biomaterial
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Selenium suppresses staph on implant material
(Date:7/31/2015)... Kina, 31. juli 2015 Den 10. internationale ... af BGI fra den 22. - 25. oktober i ... fejrer sin 10-års fødselsdag i år. Siden starten i ... årlige møder på ,omik,-feltet, og er en af de ... ICG-10 fokuserer på nylige gennembrud og fremskridt inden ...
(Date:7/31/2015)... China , 31 de julio de 2015 /PRNewswire/ ... Genómica (ICG-10,  www.icg-10.org ) del 22 al 25 de ... . La conferencia celebra su décimo aniversario ... ha convertido en una de las reuniones anuales más ... y es una de las conferencias científicas más dinámicas, ...
(Date:7/31/2015)... 31 de julho de 2015 A 10 ... ) será realizada pela BGI de 22-25 de outubro de ... A conferência está celebrando seu 10 o. ... ICG se tornou uma das reuniões mais influentes do ... científicos mais dinâmicos, entusiastas e prazerosos. ...
Breaking Biology News(10 mins):Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3
... The destructive cellular pathways activated in Alzheimer,s ... say researchers from Georgetown University Medical Center (GUMC). ... might successfully target both conditions. In an ... Conference on Alzheimer,s Disease, the scientists will show ...
... The Federal Bureau of Investigation (FBI) has awarded ... $47 million contract to continue managing the FBI Criminal ... program. The contract covers the conversion of paper fingerprint, ... for the FBI. , , Records processed ...
... PARK, Calif., June 29 Kornberg Associates | Architects ( ... University to design a new Cognitive & Neurobiological Imaging ... The firm has worked with Stanford University ... 30 years, one of which is the two-story, 32,000 square-foot ...
Cached Biology News:Alzheimer's disease drug treats traumatic brain injury, report GUMC researchers 2Federal Bureau of Investigation Awards Lockheed Martin Biometric Card Scanning Service Contract 2Kornberg Associates Architects Selected to Develop Design for New Stanford University Imaging Center 2
(Date:7/31/2015)... , July 31, 2015 In today,s ... that help them drive positive health outcomes, improve ... source of patient care in their communities. At ... tradeshow and conference, AmerisourceBergen announced a new set ... Services Administration Organization and help independent pharmacies endure ...
(Date:7/31/2015)... ... July 31, 2015 , ... Global ... and premium industry insights on the global resorcinol industry. The report highlights the ... of vivid market scenarios and analysis of primary and secondary inputs from the ...
(Date:7/31/2015)... , July 31, 2015 China Cord Blood ... China,s leading provider of cord blood collection, ... storage services, today announced that the Company has filed ... Securities and Exchange Commission. The filed Form 20-F includes ... 31, 2015. The Form 20-F can be accessed by ...
(Date:7/31/2015)... ... July 31, 2015 , ... R-Biopharm is proud ... partially hydrolyzed gluten in foods, has been accepted by AOAC International as Official ... Gluten in Fermented Cereal-Based Products by R5 Competitive ELISA,” based on a specific ...
Breaking Biology Technology:AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 4China Cord Blood Corporation Files Its Annual Report on Form 20-F 2RIDASCREEN® Competitve Gliadin Receives AOAC Official First Action Status 2
... Everyone wants to design the dsRNA that , ... length correlate with silencing efficiency? Ambion scientists , ... dsRNA of different sizes and directed , ... (Figure 1A), were prepared using the MEGAscript RNAi Kit ...
... Large scale gene expression studies , ... purify high quality RNA from a large number of samples. Although the , ... dsRNA production and , clean up, ... format. Thus for high-throughput applications, we recommend , ...
... , ... heterogenous samples is a major challenge in studying gene , ... microdissection (LCM), developed in a collaborative ... and Arcturus, Inc. specifically to isolate , ...
Cached Biology Technology:RNAi: Size Does Matter 2RNAi for High Throughput Analysis 2RNA from LCM Samples 2RNA from LCM Samples 3
Poly A Polymerase catalyzes the addition of AMP to the 3' hydroxyl terminus of RNA. Poly A Polymerase can add poly(C) and poly(U) to RNA but does so with much-reduced efficiency....
... Preparation contains a unique β-agarose digesting enzyme ... of intact DNA and RNA from low ... in TAE, TBE, MOPS, or phosphate buffers. ... the TAE, TBE, MOPS, and phosphate electrophoresis ...
Recombinant Cat Interferon Alpha Activity: 2.7 x 10 7 u/mg...
... The RapidStak is a fast ... its class. Its high capacity ... and more confident walk away time ... and ease of set-up make for ...
Biology Products: