Navigation Links
Selenium may prevent high risk-bladder cancer
Date:12/7/2008

PHILADELPHIA A study published in the December issue of Cancer Prevention Research, a journal of the American Association for Cancer Research, suggests that selenium, a trace mineral found in grains, nuts and meats, may aid in the prevention of high-risk bladder cancer.

Researchers from Dartmouth Medical School compared selenium levels in 767 individuals newly diagnosed with bladder cancer to the levels of 1,108 individuals from the general population. Findings showed an inverse association between selenium and bladder cancer among women, some smokers and those with p53 positive bladder cancer.

In the entire study population, there was no inverse association between selenium and bladder cancer, but women (34 percent), moderate smokers (39 percent) and those with p53 positive cancer (43 percent) had significant reductions in bladder cancer with higher rates of selenium.

"There are different pathways by which bladder cancer evolves and it is thought that one of the major pathways involves alterations in the p53 gene," said corresponding author Margaret Karagas, Ph.D., professor of community and family medicine of the Norris Cotton Cancer Center at Dartmouth. "Bladder cancers stemming from these alternations are associated with more advanced disease."

While other studies have shown a similar association between selenium and bladder cancer among women, this study is one of the first to show an association between selenium and p53 positive bladder cancer.

"Ultimately, if it is true that selenium can prevent a certain subset of individuals, like women, from developing bladder cancer, or prevent certain types of tumors, such as those evolving through the p53 pathway, from developing, it gives us clues about how the tumors could be prevented in the future and potentially lead to chemopreventive efforts," Karagas said.

Karagas hopes to replicate these findings on a larger scale in order to examine the conn
'/>"/>

Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biological selenium removal: The solution to pollution?
2. Controlling for size may also prevent cancer
3. Avocados may help prevent oral cancer, OSU study shows
4. Dietary calcium could possibly prevent the spread of breast cancer to bone
5. Bilberry extract -- can it help prevent certain cancers?
6. Preventing tuberculosis reactivation
7. Knocking out cell receptor may help block fat deposits in tissues, prevent weight gain
8. Scripps research team blocks bacterial communication system to prevent deadly staph infections
9. Frontiers in Cancer Prevention Research
10. NASA technology helps predict and prevent future pandemic outbreaks
11. Childrens Hospital studying drug with the potential to prevent/delay onset of type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... GSA Bulletin study uses tree rings to ... Chaco Wash in northern New Mexico, USA. By determining ... willow, investigators were able to precisely date arroyo sedimentary ... this data with aerial imagery, LiDAR, longitudinal profiles, and ... , Arroyos are deep, oversized channels that have vertical ...
(Date:9/18/2014)... research into the Crimean-Congo hemorrhagic fever virus (CCHFV), a ... humans similar to that caused by Ebolavirus, has identified ... has the potential to lead to novel targets for ... research, reported in a paper published today in the ... at the Texas Biomedical Research Institute and their colleagues, ...
(Date:9/18/2014)... "frequent flyers" program, fruit flies surely would be eligible ... increasing numbers of fruit fly research studies. One fruit ... and another is scheduled launch to the station Sept. ... December. , Fruit flies are biomedical research models studied ... organisms can reveal the basis for health and disease ...
Breaking Biology News(10 mins):Tree rings and arroyos 2Tree rings and arroyos 3Tree rings and arroyos 4Tree rings and arroyos 5Tree rings and arroyos 6Tree rings and arroyos 7Research milestone in CCHF virus could help identify new treatments 2Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4
... cases of 2009 H1N1 influenza, the virus can damage cells ... the 1918 and 1957 influenza pandemics, report researchers from the ... Office of Chief Medical Examiner. The scientists reviewed autopsy reports, ... died of 2009 H1N1 influenza infection between May 15 and ...
... Royal Swedish Academy of Sciences will collaborate to publish AMBIO ... AMBIO was founded in 1972, the year of the ... journal addresses the scientific, social, economic and cultural factors that influence ... Springer will be published in February 2010. AMBIO ...
... salmon species will have its genome fully sequenced, ... agencies and industry from Canada, Chile and Norway. ... Economic Development Agency, InnovaChile, Norwegian Research Council, Norwegian ... the International Cooperation to Sequence the Atlantic Salmon ...
Cached Biology News:New York autopsies show 2009 H1N1 influenza virus damages entire airway 2New York autopsies show 2009 H1N1 influenza virus damages entire airway 3Springer signs co-publishing agreement with the Royal Swedish Academy of Sciences 2Genome BC collaborates with Chile and Norway to sequence salmon genome 2
(Date:9/19/2014)... -- The new , Healthcare and Life Sciences ... on PharmaBoardroom.com for free download , looks ... Spanish economy in 2009, and the austerity measures that followed, ... in times of trouble. "Despite the crisis, ... market, and the general conditions to invest are favorable to ...
(Date:9/18/2014)... -- DeepResearchReports.com adds "2014 Deep Research Report on ... Deep Research Report on Global and China Sodium ... Photo - http://photos.prnewswire.com/prnh/20140918/147058 ... China Acetic Acid Industry" is a professional and ... and Global Acetic Acid Market. The report ...
(Date:9/18/2014)... Station, Texas (PRWEB) September 18, 2014 ... System Chancellor John Sharp, Texas A&M Health Science ... the U.S. Department of Health and Human Services ... today dedicated a national pandemic influenza vaccine manufacturing ... serve as an anchor for the Texas A&M ...
(Date:9/18/2014)... 18, 2014 Research and Markets ... Albumin Industry Report 2014" report to their offering. ... 2014 is a professional and in-depth study on the ... The report provides a basic overview of the ... The human albumin market analysis is provided for the ...
Breaking Biology Technology:PharmaBoardroom Releases New Spain Pharmaceuticals Report 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 3Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 4Global Human Albumin Industry Report 2014 2Global Human Albumin Industry Report 2014 3
... MADISON - Tired of high gas costs and poor ... group of engineering students at the University of Wisconsin-Madison ... the cleanest and most fuel-efficient SUVs in North America. ... could one day be incorporated into mass-production hybrid SUVs. ...
... Doyle began turning up the heat on Republicans on ... had already turned the tables on him regarding problematic state ... subject of a state audit, recently were placed at the ... Kanavas , R-Brookfield, who has worked with the Governor on ...
... you judged Milwaukee by the economic indicators alone, you ... the dusty, bypassed town in the hit animated movie ... Hollywood ending, maybe theres a more prosperous, real-life road ... so, because without a healthy Milwaukee, most of Wisconsin ...
Cached Biology Technology:UW-Madison hybrid-vehicle team places second nationally 2GOP lawmaker faults Doyle for IT problems 2GOP lawmaker faults Doyle for IT problems 3It's an economic fact: As Milwaukee goes, so goes Wisconsin 2It's an economic fact: As Milwaukee goes, so goes Wisconsin 3
... siRNA Tracker Intracellular Localization Kit provides a ... deliver siRNA, of your design, in an ... tracking experiments. Subcellular localization and functional inhibition ... following introduction of the labeled siRNA into ...
... 60kDa (A) and 36kDa (C) subunits ... 7.5, 500mM NaCl, 60mM 2-mercaptoethanol, 1mM ... DTT, and 0.1mg/ml serum albumin Properites: ... proteins. Purification: DEAE chromatography, aminohexyl-agarose and ...
... Label IT siRNA Tracker Intracellular Localization Kit ... label and deliver siRNA, of your design, ... in vitro tracking experiments. Subcellular localization and ... be monitored following introduction of the labeled ...
... The Label IT siRNA Tracker Intracellular ... provides a straight forward approach to ... your design, in an efficient yet ... experiments. Subcellular localization and functional inhibition ...
Biology Products: