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Seeing a bionic eye on medicine's horizon
Date:3/22/2010

Television's Six Million Dollar Man foresaw a future when man and machine would become one. New research at Tel Aviv University is making this futuristic "vision" of bionics a reality.

Prof. Yael Hanein of Tel Aviv University's School of Electrical Engineering has foundational research that may give sight to blind eyes, merging retinal nerves with electrodes to stimulate cell growth. Successful so far in animal models, this research may one day lay the groundwork for retinal implants in people.

But that's a way off, she says. Until then, her half-human, half-machine invention can be used by drug developers investigating new compounds or formulations to treat delicate nerve tissues in the brain. Prof. Hanein's research group published its work recently in the journal Nanotechnology.

Implanting the idea

"We're working to interface man-made technology with neurons," says Prof. Hanein. "It can be helpful in in vitro and in in vivo applications, and provides an understanding of how neurons work so we can build better devices and drugs," she says.

She's developed a spaghetti like mass of nano-sized (one-millionth of a millimetre) carbon tubes, and using an electric current has managed to coax living neurons from the brains of rats to grow on this man-made structure. The growth of living cells on the nano substrate is a very complicated process, she says, but they adhere well to the structure, fusing with the synthetic electrical and physical interface. Using the new technology developed in Prof. Hanein's laboratory, her graduate student Mark Shein has been observing how neurons communicate and work together.

"We are attempting to answer very basic questions in science," Prof. Hanein explains. "Neurons migrate and assemble themselves, and using approaches we've developed, we are now able to 'listen' to the way the neurons fire and communicate with one another using electrical impulses. Listening
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Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

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