Navigation Links
Secondhand smoke exposure in childhood increases lung cancer risk later in life
Date:12/2/2009

PHILADELPHIA Children exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.

Results of this study are published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, as part of a special tobacco focus in the December issue.

This year alone, more than 219,000 Americans will be diagnosed with lung cancer; more than 159,000 will die from it and some of those may be people who have never smoked. Studies to date have shown that exposure to secondhand smoke in adulthood has detrimental health effects, but data are limited on one's risk of developing lung cancer when exposed as a child.

What makes this study different from previous research is that it was conducted in two independent cohorts and included a molecular analysis of gene variants of innate immunity the mannose binding lection-2 gene, or MBL2 gene. The MBL2 gene is known to affect susceptibility to respiratory diseases.

Using the ongoing National Cancer Institute-Maryland Lung Cancer study (624 cases; 348 controls), Curtis C. Harris, M.D., chief of the Laboratory of Human Carcinogenesis at NCI, and colleagues collected information on secondhand smoke history among men and women. They used DNA for genotyping the MBL2 gene. Then, to compare, Harris, Ping Yang, M.D., Ph.D., professor of epidemiology at the Mayo Clinic in Rochester, Minn., and colleagues used results from a Mayo Clinic study (461 never smokers; 172 cases; 289 controls).

Harris and colleagues found an association between childhood exposure to secondhand tobacco smoke and increased risk of lung cancer in adulthood. Furthermore, MBL2 activity was associated with an even more increased risk among those who were exposed to secondhand smoke in childhood.

Based on the results of this study, Harris said "children should not be exposed to secondhand tobacco sm
'/>"/>

Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Exposure to secondhand cigarette smoke over a lifetime increased breast cancer risk later in life
2. Cigarette smoke, alcohol damage hearts worse as combo
3. Vitamin E may increase tuberculosis risk in male smokers with high vitamin C intake
4. Scientists discover how cigarette smoke causes cancer: Study points to new treatments, safer tobacco
5. Fire without smoke
6. Alzheimers starts earlier for heavy drinkers, smokers
7. Fruits, vegetables and teas may protect smokers from lung cancer, UCLA researchers report
8. If your first cigarette gave you a buzz and you now smoke, a gene may be to blame
9. Infection blocks lungs protective response against tobacco smoke
10. Smoke smudges Mexico Citys air, chemists identify sources
11. Book explores global implications of wildland fire smoke
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Secondhand smoke exposure in childhood increases lung cancer risk later in life
(Date:9/18/2014)... turned its newborn screening program into a model other states ... the first-ever Newborn Screening Quality Award from the March of ... M.P.H., Arizona,s Department of Health Services director, with the award ... policy of full transparency for the length of time it ... lab for analysis, and set a target of having 95 ...
(Date:9/18/2014)... Eight researchers from several disciplines will be celebrated tonight ... their roles in improving the health of premature infants ... supercomputing revolutions. The researchers, whose work was supported by ... and the former Atomic Energy Commission, will be honored ... Washington, DC. A bipartisan group of Members of Congress ...
(Date:9/18/2014)... September 18, 2014 Elsevier, a world-leading provider ... services, and the Australasian Research Management Society (ARMS), ... scientists at the 5th Scopus Young Researcher of ... earlier today at the National Convention Centre and ... was attended by guests representing Australia,s and New ...
Breaking Biology News(10 mins):March of Dimes honors Arizona with first-ever newborn screening award 2March of Dimes honors Arizona with first-ever newborn screening award 33rd annual Golden Goose award ceremony honors 8 researchers; Unusual work had big results 2Elsevier and Australasian Research Management Society award scientists at Scopus ceremony 2
... 50,000, were awarded to young researchers working in Belgium, Canada, ... on the basis of their outstanding research proposals, were announced ... 2010 (IOF WCO-ECCEO10) taking place in Florence, Italy until May ... of maternal vitamin D status during pregnancy on post pubertal ...
... Tech Professor John A. Burns will receive a prestigious ... computational methods for, and applications in, the control, design, ... T. and Idelia Reid Prize in Mathematics will be ... and Applied Mathematics Annual Meeting which will take place ...
... (AML) is relatively rare in children, drinking alcohol during ... paper published in Cancer Epidemiology, Biomarkers & Prevention ... Research. Julie Ross, Ph.D., director of the division ... of Minnesota, said there are about 700 cases of ...
Cached Biology News:Virginia Tech mathematician wins international award 2Virginia Tech mathematician wins international award 3
(Date:9/18/2014)... diseases that afflict skeletal growth through abnormalities in ... fetal stage and is caused by genetic mutations. ... factor receptor 3 (FGFR3) has been associated with ... a skeletal dysplasia that cause serious respiratory problems ... (ACH), which causes stunted growth and other complications ...
(Date:9/18/2014)... Scientists at USC have developed a new microscopy ... in living animals at higher-than-ever resolution. , Dubbed ... allows imaging resolutions that are an order of ... insights into the behavior of biomolecules at the ... Sept. 18 by Nature Communications , the ...
(Date:9/18/2014)... Silicon-valley Electronic Data Capture (EDC) provider ... , the latest addition to Clinovo’s CRO Partnership Program. ... (CRO) Program, Clinovo further expands its global reach to ... training, we are now able to build studies on ... can also rely on Clinovo to fully support the ...
(Date:9/18/2014)... Whitehouse Laboratories is pleased to announce that ... has acquired an additional 4,000 square feet of dedicated ... adjacent to its current package testing facility. The official ... Whitehouse Labs is in the process of upgrading the ... testing. The prime location enables Whitehouse Labs to immediately ...
Breaking Biology Technology:Researchers use iPS cells to show statin effects on diseased bone 2Researchers use iPS cells to show statin effects on diseased bone 3Scientists pioneer microscopy technique that yields fresh data on muscular dystrophy 2Digitaliza TXT Joins Clinovo’s CRO Partnership Program, Bringing Its Open Source EDC System, ClinCapture to Latin America 2Digitaliza TXT Joins Clinovo’s CRO Partnership Program, Bringing Its Open Source EDC System, ClinCapture to Latin America 3Whitehouse Labs Announces Package Testing Laboratory Expansion 2Whitehouse Labs Announces Package Testing Laboratory Expansion 3Whitehouse Labs Announces Package Testing Laboratory Expansion 4
... and Marketed ... ... May 1 ,EUSA Pharma Inc (,EUSA,), a transatlantic specialty pharmaceutical ... that,it has divested its monoclonal antibody research business to the ...
... 1 Vical Incorporated (Nasdaq:,VICL) today announced that the ... 31, 2008, before the opening of trading on,Thursday, May ... discuss the,financial results and provide a company update at ... open on a listen-only basis to any interested,parties. The ...
... DIEGO, May 1 Favrille, Inc. (Nasdaq:,FVRL), a ... of cancer, announced today that it will,host a ... Eastern Time on,Thursday, May 8, 2008 to discuss ... release will be issued after the U.S. stock ...
Cached Biology Technology:EUSA Pharma Divests Monoclonal Antibody Research Business and Early-Stage Oncology Product 2EUSA Pharma Divests Monoclonal Antibody Research Business and Early-Stage Oncology Product 3Vical Announces News Release and Conference Call Schedule for First Quarter 2008 Financial Results 2Favrille to Host Conference Call and Live Webcast to Discuss First Quarter 2008 Financial Results on May 8, 2008 2
... ChipWriter Pro system, 220-240 V, uses floating ... oligonucleotides, carbohydrates, lipids, and other biomolecules onto ... This system can generate high-density arrays with ... or greater than 57,000 spots per membrane ...
... Ciphergen's ProteinChip arrays have been ... from biological samples. A variety of ... of proteins according to their unique ... different spots, allowing side-by-side sample comparison, ...
The SmartSpec printer paper is used to record data generated by the SmartSpec Plus spectrophotometer. Supplied as 5 packs....
... been developed for affinity capture of ... of ProteinChip chemical surfaces allow differential ... unique biochemical properties. Each chip has ... comparison, and the chips are color-coded ...
Biology Products: